Adam Louis Kenet

Adam is a second-year MD-PhD student from New York City. He graduated from Johns Hopkins University with a major in Biomedical Engineering (Immunoengineering focus area) and a minor in Computational Medicine. At Johns Hopkins, Adam joined Dr. Anthony Leung’s lab in the Department of Biochemistry and Molecular Biology, where he studied the biophysical properties of poly(ADP-ribose). He worked on projects using experimental and simulated smFRET data to investigate the flexibility of poly(ADP-ribose) polymers and their interactions with proteins. For his senior project, Adam led a team of students applying machine learning to clinical data (i.e., ECG, vital signs, and labs) to develop a risk score to predict cardiac arrest in the pediatric intensive care unit before onset. After graduation, Adam spent two years working in Dr. Grégoire Altan-Bonnet’s lab at the National Cancer Institute of the NIH. There, Adam used computational and experimental methods to model tumor response to CAR-T cells in order to understand tumor relapse behavior. He helped develop a Python package that automatically processes bioluminescent tumor images, quantifies tumor burden, classifies tumor behavior, and parametrizes tumor dynamics. He then applied this pipeline to a large set of pre-clinical experiments (n>1000 mice) conducted to assess the potency of CAR-T cells against leukemia. While in Maryland, Adam also worked as an EMT with the Baltimore County and Montgomery County Fire Departments.