
Aiqun Li, PhD
About Me
Dr. Aiqun Li is an Associate Professor in the Department of Genetics and Genomic Sciences. He is working on validating novel targets for Alzheimer’s disease (AD) using stem cells, CRISPR systems, and next-generation sequencing.
Dr. Li earned his B.S. and M.S. in Medicine from Nanjing Medical University in 2000 and 2003. He then received his Ph.D. in Biochemistry and Molecular Biology from the Chinese Academy of Sciences in 2006. He conducted his postdoctoral training at Weill Cornell Medicine during 2007-2011. He joined NYSCF as a Staff Scientist, leading the NYSCF-Golub Stem Cell Research Initiative for Parkinson’s Disease (PD) in 2011, and served as an NYSCF Investigator since 2016. Dr. Li was the recipient of the P&G Award for Outstanding Graduate Student, the Shanghai-Unilever Research & Development Fund, the Bachmann-Strauss Dystonia & Parkinson’s Foundation Research Grant, the Parkinson’s Disease Foundation Lucien Côté Early Investigator Award, the New York Community Trust Grant, the Michael J. Fox Foundation Target Validation Pilot Award, and the 2020 Friedman Brain Institute (FBI) Research Scholar.
Language
English
Position
ASSOCIATE PROFESSOR | Genetics and Genomic Sciences
Research Topics
Alzheimer's Disease, Drug Design and Discovery, Gene editing, Neuro-degeneration/protection, Stem Cells
Publications
Selected Publications
- Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease. Yong Huang, Minghui Wang, Haofei Ni, Jinglong Zhang, Aiqun Li, Bin Hu, Chrystian Junqueira Alves, Shalaka Wahane, Mitzy Rios de Anda, Lap Ho, Yuhuan Li, Sangjo Kang, Ryan Neff, Ana Kostic, Joseph D. Buxbaum, John F. Crary, Kristen J. Brennand, Bin Zhang, Hongyan Zou, Roland H. Friedel. Nature Neuroscience
- Multi-omic profiling of the developing human cerebral cortex at the single-cell level. Kaiyi Zhu, Jaroslav Bendl, Samir Rahman, James M. Vicari, Claire Coleman, Tereza Clarence, Ovaun Latouche, Nadejda M. Tsankova, Aiqun Li, Kristen J. Brennand, Donghoon Lee, Guo Cheng Yuan, John F. Fullard, Panos Roussos. Science advances
- Convergent coexpression of autism-associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies. Calwing Liao, Mariana Moyses-Oliveira, Celine E.F. De Esch, Riya Bhavsar, Xander Nuttle, Aiqun Li, Alex Yu, Nicholas D. Burt, Serkan Erdin, Jack M. Fu, Minghui Wang, Theodore Morley, Lide Han, Patrick A. Dion, Guy A. Rouleau, Bin Zhang, Kristen J. Brennand, Michael E. Talkowski, Douglas M. Ruderfer. Cell Genomics