Alan J Moskowitz, MD

Dr. Moskowitz is Co-director of the International Center for Health Outcomes and Innovation Research (InCHOIR), with over 15 years of experience in directing both clinical and data coordinating centers for multicenter clinical trials, both NIH and industry sponsored. He has expertise in designing clinical trials, and overseeing the development of web-based data collection instruments, data management, study monitoring, committee management, interim and final analysis and publication of results. In addition to such traditional endpoints as survival he has expertise with health resource use, quality of life, patient preferences, and functional status. Among other NIH supported clinical trials, he previously directed the clinical coordinating center for the REMATCH trial (left ventricular assist devices (LVAD) as a “destination therapy – 20 clinical centers). In addition to survival, quality of life and patient preferences were key endpoints for this trial. He has also co-directed the DCC for an NHLBI SCCOR project on LVADs and heart failure (12 clinical centers), which conducted multicenter observational and interventional studies related to infection, consumptive coagulopathy and cell therapy for cardiac regeneration. He currently directs the data coordinating center for the NINDS sponsored ARUBA trial (70 clinical centers worldwide) comparing watchful waiting to immediate intervention for patients with unruptured brain AVMS.

Dr. Moskowitz has been in the leadership team for the NHLBI support Cardiothoracic Surgical Trials Network (CTSN) to which he brings expertise in design and analysis of cardiac and neurological trials, functional status, quality of life and economic endpoints.  He oversees the adverse event review process and the Biorepository, including the development of a mechanistic study research agenda.