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Alex Manini, MD
Emergency Medicine
About Me
Alex F. Manini, MD, MS, FACMT, FAACT, is a Professor of Emergency Medicine at the Icahn School of Medicine at Mount Sinai and practices clinically at Elmhurst Hospital Center in New York City. Dr. Manini is the Director of the Mount Sinai Center for Research on Emerging Substances, Poisoning, Overdose, and New Discoveries (RESPOND Center), and the Associate Program Director of the T32 Clinician Scientist Training Program focused on emergency care research.
Dr. Manini’s research track record is highlighted by being continuously funded by the National Institutes of Health (NIH) since 2009, totaling over $10M as a principal investigator. He is consistently ranked among the top 30 highest NIH-funded PIs in emergency medicine, as recognized by the Blue Ridge Institute for Medical Research. Additionally, he has published over 110 peer-reviewed articles in the emergency medicine and medical toxicology literature. He has mentored over 40 pre- and post-doctoral students, residents, and junior faculty over the past 15+ years at Mount Sinai, who have gone on to secure several millions of dollars in federal grant funding.
Before joining Mount Sinai, Dr. Manini was a medical toxicology fellow at NYU/Bellevue where he completed a Master of Science in Clinical Investigation at NYU School of Medicine. He was trained in emergency medicine at Massachusetts General Hospital and Brigham and Women’s Hospital in the Harvard Affiliated Emergency Medicine Residency.
Additional Training:
Medical Toxicology Fellowship, NYU / Bellevue / NYC Poison Control Center
Emergency Medicine Residency, Harvard Affiliated Emergency Medicine Residency
Master of Science, NYU School of Medicine
Doctor of Medicine, UCSF School of Medicine
Bachelor of Science, MIT
Language
English
Position
PROFESSOR | Emergency Medicine
Hospital Affiliations
- Mount Sinai Morningside
- Mount Sinai Beth Israel
- Mount Sinai Brooklyn
- Mount Sinai Queens
- The Mount Sinai Hospital
- Mount Sinai West
Clinical Focus
- Toxicology
Education
BS, Massachusetts Institute of Technology
MD, University of California San Francisco
, Brigham & Women's Hospital / Massachusetts General Hospital Harvard Medical School
, Brigham & Women's Hospital / Massachusetts General Hospital Harvard Medical School
MS, New York University
, Bellevue Hospital Center - NYU School of Medicine
MD, UCSF School of Medicine
Residency, Emergency Medicine
Brigham and Women's Hospital
Fellowship, Emergency Medicine, Medical Toxicology
NYU Grossman School of Medicine
Certifications
American Board of Emergency Medicine
Awards
2014
NIH Study Section Member, CEBRA (Cutting Edge Basic Research Awards)
2014
Top Consultant, Annals of Emergency Medicine
2013
Young Investigator Award WINNER, XXXIII International Congress
EAPCCT
2013
Senior Reviewer
Annals of Emergency Medicine
2013
Fellow of the American College of Medical Toxicology
FACMT
2013
NIH Early Career Reviewer (ECR), Center for Scientiic Review
2011
The Dr. Harold and Golden Lamport Reseach Award
Mount Sinai School of Medicine
2011
Young Investigator of the Year
Society of Academic Emergency Medicine (SAEM)
Research
In 2015, Dr. Manini received the Empire Clinical Research Investigator Program (ECRIP) from the New York, State Department of Health entitled Simulation Outcomes Research for ACLS. He also received Promotion of Diversity in Health Related Research from the National Institute on Drug Abuse entitled, Opiate co-ingestion as a risk factor for acetaminophen hepatotoxicity. Additionally, Dr. Manini received from the NIH an Administrative Supplement from the National Institute on Drug Abuse (NIH/NIDA) entitled Assessment of novel serum biomarkers.
In 2014, Dr. Manini received a five-year Research Project Grant (R01) from the National Institute on Drug Abuse at the NIH. The award involves collaboration between Mount Sinai investigators in neuroscience, cardiology, epidemiology, emergency medicine, and medical toxicology, along with co-investigators from the NYU School of Medicine and the Toxicology Investigators’ Consortium, a national registry sponsored by the American College of Medical Toxicology. Clinical studies launched by the R01 will test a broad array of risk prediction instruments, laboratory biomarkers, and opioid receptor gene polymorphisms, with the goal to produce clinical tools to individualize prevention strategies for curtailing the national rise in drug overdose fatality.
In 2014, Dr. Manini was appointed Site PI of the NIDA National Early Warning System Network (iN3). The study is funded by an NIH High Priority Short Term Project (R56) from the National Institute on Drug Abuse. The goal of the study is to identify new episodes of emerging drug use nationally to advance drug surveillance from a reactive to anticipatory science.
In 2009, Dr. Manini received a Career Development Grant Award (K23) from the National Institute on Drug Abuse at the NIH. Mentored by David Vlahov, PhD and Lynne Richardson, MD, Dr. Manini studied clinical risk factors for adverse cardiovascular events in drug overdose emergencies.
Insurance Information
Accepted insurance may vary by the doctor’s office location. Please contact the office directly to obtain the most up-to-date insurance information.
- CIGNA Healthcare
- Centivo
- Empire Blue Cross Blue Shield - Commercial/Exchange
- Empire Blue Cross Blue Shield - HealthPlus Medicaid
- Empire Blue Cross Blue Shield - Medicare
- Horizon NJ
- Medicare - NJ
- Medicare - NY
- Metroplus
- NJ Medicaid
- NY Medicaid
- Oscar
- Oxford - Freedom and Liberty
- United Health Care - Commercial
- United Health Care - Empire Plan
- United Health Care - Oxford Care
- VNSNY Select Health Medicaid
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.
Publications
Selected Publications
- Disparities in Treatment and Referral After an Opioid Overdose Among Emergency Department Patients. Siri Shastry, Joseph Carpenter, Alex Krotulski, Jeffrey Brent, Paul Wax, Kim Aldy, Sharan Campleman, Rachel Culbreth, Alyssa Falise, Adrienne Hughes, Robert G. Hendrickson, Alexandra Amaducci, Bryan Judge, Christopher Meaden, Diane P. Calello, Jennie Buchanan, Joshua Shulman, Michael Levine, Evan Schwarz, Alex F. Manini. JAMA network open
- Response to “Comment on Naloxone Dosing and Hospitalization for Nitazene Overdose: A Scoping Review”. Jonathan Berger, Mohamed Jalloh, Alec Severe, Alex Manini. Journal of Medical Toxicology
- Risk of Delayed Intubation After Presumed Opioid Overdose in the Emergency Department. Daniel J. McCabe, Heath Gibbs, Alessandra A. Pratt, Rachel Culbreth, Amanda M. Sutphin, Stephanie Abston, Shao Li, Paul Wax, Jeffrey Brent, Sharan Campleman, Kim Aldy, Alyssa Falise, Alex F. Manini. Annals of Emergency Medicine
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Manini has not yet completed reporting of Industry relationships.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.