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Profile image of Anne Schaefer

    Anne Schaefer, MD, PhD

    Education

    MD, Johannes Gutenberg University

    MD, Charité University

    Postdoc, The Rockefeller University

    Awards

    2018

    Inaugural NINDS Landis Award for Outstanding Mentorship

    NIH NINDS

    2018

    Inventor of the Year 2018 Award

    Mount Sinai

    2015

    Harold and Golden Lamport Research Award

    Mount Sinai

    2014

    Technology Development Fund Award

    Mount Sinai Innovation

    2014

    Cure Challenge Award

    Cure Challenge

    2014

    Kavli Frontiers in Science Fellow

    The National Academy of Science

    2012

    Chrissy Rossi Investigator

    Chrissy Rossi

    2012

    Research Award

    Seaver Autism Center

    2012

    NIH Director’s New Innovator Award

    NIH

    2011

    NARSAD Young Investigator Award

    NARSAD

    2006

    Research Fellowship

    German Research Foundation DFG

    2005

    Hans-Hench Award 2005

    German Society for Immunology, Germany

    2004

    Summa cum lauden

    Charité University Berlin

    2003

    Research Award

    Keystone Scholar Travel Award

    2001

    USA Research Scholarship

    The German National Academic Foundation

    1999

    Scholarship

    German National Merit Foundation

    Research

    Our research focuses on identifying the epigenetic basis of neurodegenerative and psychiatric disorders. We study how miRNAs and histone modifying enzymes contribute to the establishment and maintenance of neuronal identity and specialized functions. We are particularly interested in understanding the epigenetic mechanisms of cellular plasticity and its role in regulation of microglia-neuron communication in health and disease. One of the major focuses of our research lies in the development of animal models of human neurological disease associated with abnormal function of epigenetic regulators of different types. Using pioneering technologies including cell type specific analysis of mRNAs, miRNAs and chromatin modifications in neurons in vivo, our research aims at understanding the mechanism of neurological disorders and at their potential treatment by targeting the neuronal epigenome.