Anthony Del Signore
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Anthony Del Signore, MD

Head and Neck Surgery

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About Me

Anthony G. Del Signore, MD, PharmD is Assistant Professor in the Department of Otolaryngology and Director of Rhinology and Endoscopic Skull Base Surgery at Mount Sinai Beth Israel. He received his medical degree from the Warren Alpert School of Medicine at Brown University and subsequently completed his residency in Otolaryngology—Head and Neck Surgery at Icahn School of Medicine at Mount Sinai Hospital. He then went on to pursue a fellowship in Advanced Rhinology and Endoscopic Skull Base Surgery at University of North Carolina, training with some of the preeminent leaders in the field.

Dr. Del Signore’s specific clinical interests include medical and surgical management of chronic sinusitis, paranasal sinus and skull base tumors, orbital tumors, encephalocele repair, cerebrospinal fluid leaks (CSF), balloon sinuplasty, Eustachian tube dilation and allergic disease.  His particular training allows providing treatment via endoscopic minimally invasive techniques and office based procedures. His current research is focused on health outcomes following skull base surgery, implementation of sinus treatment protocols and surgical intervention, and introduction and use of the ever changing technology in the practice of rhinology.

Dr. Del Signore has been active in clinical research and has co-authored many textbook chapters and published manuscripts in peer-reviewed journals in rhinology, neurosurgery and otolaryngology. He is an active member and presenter at the national meetings of the American Rhinologic Society, Triological Society, American Academy of Otolaryngology-Head and Neck Surgery, and the North American Skull Base Society.

Dr. Del Signore also performs humanitarian surgical missions on an international level, most recently to Cambodia and Vietnam. He has been an integral part in providing clinical evaluation and educational direction during otolaryngology seminars to local providers, and offering surgical expertise for difficult endoscopic procedures.

A member of the Mount Sinai Beth Israel Rhinology and Skull Base Surgery team, Dr. Del Signore is committed to providing exceptional, direct-access patient care. He is available for short-notice consultations for patients with sinonasal disorders and skull base tumors.

Language
English, Italian, Spanish
Position
ASSISTANT PROFESSOR | Otolaryngology, ASSOCIATE PROFESSOR | Artificial Intelligence and Human Health
Hospital Affiliations
  • Mount Sinai Beth Israel
  • Mount Sinai Morningside
  • Mount Sinai Brooklyn
  • Mount Sinai Queens
  • The Mount Sinai Hospital
  • New York Eye and Ear Infirmary of Mount Sinai
  • Mount Sinai West

Clinical Focus

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Education

MD, Warren Alpert Medical School at Brown University
Internship, Surgery (General Surgery)

Mount Sinai Hospital

Residency, Otolaryngology

Mount Sinai Hospital

Fellowship, Rhinoplasty

UNC Hospitals

Certifications

American Board of Otolaryngology

Locations

Insurance Information

Accepted insurance may vary by the doctor’s office location. Please contact the office directly to obtain the most up-to-date insurance information.

Patients with Cigna Medicare Advantage or Humana Medicare Advantage insurance: Please read this important message before booking to find out if out-of-network costs may apply to your next visit.

  • Mount Sinai Union Square10 Union Square East, Suite 5B, New York, NY, 10003
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Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).

Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.

Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.

Patient Experience Star Ratings and Comments

The Patient Experience Star Rating reflects our patients’ perception of how well their Mount Sinai provider communicated with them during an office visit. The Star Rating is based on patient responses to three questions on a patient experience survey, a standardized questionnaire sent to verified patients and distributed by a third party vendor, Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score.


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Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Del Signore during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Neurent Medical LTD

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.