
Chris Gennings, PhD
About Me
Dr. Chris Gennings is Director of the Division of Biostatistics and Research Professor in the Department of Environmental Medicine at the Icahn School of Medicine at Mount Sinai and holds a secondary appointment as Research Professor in the Department of Population Health Science and Policy.
An expert in mixtures statistics, Dr. Gennings has been actively engaged in the field for more than 35 years. Her research interests have focused on design and analysis methodologies for studies of chemical mixtures. This has included methods for both toxicology and epidemiology/clinical studies. Recent work includes development of weighted quantile sum (WQS) regression with extensions – a method that is robust to confounding concerns based on complex correlations among exposure to environmental mixtures; development of a personalized nutrition index called My Nutrition Index; development of tests for sufficient similarity, a novel approach that complements current cumulative risk assessment methods and does not require the default assumption of additivity; extensions to the distributed lag model that accommodates mixtures, called lagged WQS; and a new class of nonlinear statistical models that incorporate and evaluate regulatory guideline values in analyses of health effects associated with exposure to chemical mixtures.
At Mount Sinai, Dr. Gennings serves as Director of the Statistical Services Resource for the Human Health Exposure Analysis Resource (HHEAR) Data Center, which provides multi-disciplinary expertise in statistics, epidemiology, and bioinformatics for collaboration within the broader environmental health research community. She is also Director of the Biostatistical Core for the P30 Center on Health and Environment Across the LifeSpan (HEALS).
Prior to joining Mount Sinai in 2014, Dr. Gennings held positions at the Virginia Commonwealth University, including as Professor in the Department of Biostatistics and Director for the Research Incubator for the Center for Clinical and Translational Research.
At Mount Sinai, Dr. Gennings serves as Director of the Statistical Services Resource for the Human Health Exposure Analysis Resource (HHEAR) Data Center, which provides multi-disciplinary expertise in statistics, epidemiology, and bioinformatics for collaboration within the broader environmental health research community. She is also Director of the Biostatistical Core for the P30 Center on Health and Environment Across the LifeSpan (HEALS).
Prior to joining Mount Sinai in 2014, Dr. Gennings held positions at the Virginia Commonwealth University, including as Professor in the Department of Biostatistics and Director for the Research Incubator for the Center for Clinical and Translational Research.
Language
English
Position
PROFESSOR | Environmental Medicine, PROFESSOR | Population Health Science and Policy
Education
BA, University of Richmond
PhD, Virginia Commonwealth University
Publications
Selected Publications
- Exposure to a mixture of endocrine disrupting chemicals and thyroid function tests in pregnant women in the SELMA study. Arash Derakhshan, Eva Tanner, Marlene Stratmann, Huan Shu, Robin P. Peeters, Barbara Demeneix, Chris Gennings, Tim I.M. Korevaar, Carl Gustaf Bornehag. International Journal of Hygiene and Environmental Health
- The development of the Human Health Exposure Analysis Resource (HHEAR) Data Repository for environmental epidemiology research. Jeanette A. Stingone, Sofia Bengoa, Carolina Valle, James Masters, Tyrone Cadenhead, Alona Rabin, Paulo Pinheiro, Moira Bixby, Matthew Mazzella, Emily Spear, Henrique Santos, Chris Gennings, Deborah McGuinness, Patricia Kovatch, Nancy Mervish, Susan L. Teitelbaum. Environment international
- Food insecurity modifies the association between the gut microbiome and the risk of cognitive impairment in adults. Shoshannah Eggers, Zachary E. Hoggarth, Kiran Nagdeo, Maria J. Banas, Jamil M. Lane, Elza Rechtman, Chris Gennings, Elizabeth O’Neal, Paul E. Peppard, Ajay K. Sethi, Nasia Safdar, Kristen M.C. Malecki, Amy A. Schultz, Vishal Midya. npj Aging