
Corina Lesseur Perez, PhD, MD
About Me
Dr. Corina Lesseur is a molecular epidemiologist and serves as Assistant Professor in the Department of Environmental Medicine and the Department of Pediatrics at the Icahn School of Medicine at Mount Sinai. She is a member of the Mount Sinai Institute for Exposomic Research, the Center on Health and Environment Across the LifeSpan (HEALS), and the Mindich Child Health and Development Institute.
Dr. Lesseur’s research focuses on understanding how molecular traits shape individual disease susceptibility and responses to environmental exposures. She is particularly interested in placental epi/genomics, maternal and infant metabolic outcomes (birth weight, maternal obesity, and gestational diabetes) and in the effects of environmental exposures in early-life programming. Dr. Lesseur work is supported by an R00 grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development entitled “Integrative analysis of human placental epi/genome in relation to fetal growth” (R00HD097286). In 2020, Dr. Lesseur was awarded the March of Dimes Basil O’Connor Starter Scholar Research Award that funds the project entitled “Characterizing the effects of genetics and gestational diabetes on the placental DNA methylome of Pacific Islanders”.
Dr. Lesseur received her MD at the Central University of Venezuela and a PhD in Molecular and Experimental Medicine from Dartmouth College. She completed a postdoctoral fellowship in Genetic Epidemiology at the International Agency for Research in Cancer, followed by postdoctoral training in environmental health and molecular epidemiology at the Icahn Mount Sinai.
Language
English
Position
ASSISTANT PROFESSOR | Environmental Medicine
Multi-Disciplinary Training Areas
Artificial Intelligence and Emerging Technologies in Medicine [AIET], Genetics and Genomic Sciences [GGS]
Education
MD, Luis Razetti School of Medicine, Central University of Venezuela (Caracas, Venezuela)
PhD, Geisel School of Medicine at Dartmouth College (NH, USA)
Awards
2020
March of Dimes Basil O’Connor Starter Scholar Research Award entitled: “Characterizing the effects of genetics and gestational diabetes on the placental DNA methylome of Pacific Islanders.”
2020
Mount Sinai Transdisciplinary Center on Early Environmental Exposures, P30 pilot research grant entitled: “Spatial exploration of inter‑relationships of covid‑19 infection, metal exposure, transcriptome and immune response in human placentas.”
2019
K99‑HD097286 NIH/NICHD research grant entitled: “Integrative analysis of human placental epi/genome in relation to fetal growth.”
2017
Mount Sinai Transdisciplinary Center on Early Environmental Exposures, P30 pilot research grant entitled: “Transcriptome and endocrine effects of glyphosate‑based herbicides in early life.”
2014
Marie Curie co‑funded postdoctoral fellowship for training in cancer research at the International Agency for Research in Cancer (IARC)
Publications
Selected Publications
- Potentially causal associations between placental DNA methylation and schizophrenia and other neuropsychiatric disorders. Ariadna Cilleros-Portet, Corina Lesseur, Sergi Marí, Marta Cosin-Tomas, Manuel Lozano, Amaia Irizar, Amber Burt, Iraia García-Santisteban, Diego Garrido-Martín, Geòrgia Escaramís, Alba Hernangomez-Laderas, Raquel Soler-Blasco, Charles E. Breeze, Bárbara P. Gonzalez-Garcia, Loreto Santa-Marina, Jia Chen, Sabrina Llop, Mariana F. Fernández, Martine Vrijheid, Jesús Ibarluzea, Mònica Guxens, Carmen Marsit, Mariona Bustamante, Jose Ramon Bilbao, Nora Fernandez-Jimenez. Nature Communications
- Saliva as a potential diagnostic medium: DNA methylation biomarkers for disorders beyond the oral cavity. Alba Hernangomez-Laderas, Ariadna Cilleros-Portet, Sergi Marí, Bárbara P. González-García, Ane Arregi, Alba Jimeno-Romero, Amaia Irizar, Iraia García-Santisteban, Corina Lesseur, Nora Fernandez-Jimenez, Jose Ramon Bilbao. npj Genomic Medicine
- High-dimensional mediation analysis to elucidate the role of metabolites in the association between PFAS exposure and reduced SARS-CoV-2 IgG in pregnancy. Haibin Guan, Jia Chen, Kirtan Kaur, Bushra Amreen, Corina Lesseur, Georgia Dolios, Syam S. Andra, Srinivasan Narasimhan, Divya Pulivarthi, Vishal Midya, Lotje D. De Witte, Veerle Bergink, Anna Sophie Rommel, Lauren M. Petrick. Science of the Total Environment