
Dinesh Barupal, PhD
About Me
Dinesh Barupal, PhD is an Associate Professor in the Department of Environmental Medicine at the Icahn School of Medicine at Mount Sinai. Since 2020, He is leading the Integrated Data Science Laboratory for Metabolomics and Exposomics (IDSL.ME). His research focuses on understanding exposome-induced metabolic dys-regulations and their relationships with chronic diseases. His group develops and implements novel computational methods for large-scale metabolomics and exposomics studies with a specialization in metabolic epidemiology, computational metabolomics, metabolic bioinformatics, biomedical text mining and the blood exposome. Dr Barupal is a leading computational biologist and exposure data scientist and over the past decade has developed several bioinformatics methods, including ChemRICH, MetaMapp, IDSL.GOA , the Blood Exposome Database and the Exposome Correlation and Interpretation Database (ECID) to process and interpret metabolomics and exposomics datasets in the context of human metabolic biochemistry and exposure biology. He is PI for a NIH funded Biomedical Knowledgebase ECID (U24ES035386). His laboratory has also published several R packages (IDSL.IPA, IDSL.UFA, IDSL.CSA) and Python workflow (IDSL_MINT) to process and annotate high-resolution mass mass spectrometry untargeted metabolomics and exposomics datasets. These resources are available at the lab's Github page. Dr Barupal received his Doctoral and Post-Doctoral training at the University of California, Davis with Prof. Oliver Fiehn. He was a senior scientist in metabolomics and bioinformatics at the International Agency for Research on Cancer (IARC), World Health Organization in Lyon France (2012-2015) and the West Coast Metabolomics Center, UC Davis (2016-2020).
Language
English
Position
ASSOCIATE PROFESSOR | Environmental Medicine, ASSOCIATE PROFESSOR | Public Policy
Research Topics
Alzheimer's Disease, Biochemistry, Bioinformatics, Cancer, Computational Biology, Environmental Health, Epidemiology, Mass Spectrometry, Metabolism, Metabolomics, Public Health, Systems Biology
Multi-Disciplinary Training Areas
Artificial Intelligence and Emerging Technologies in Medicine [AIET], Cancer Biology [CAB], Disease Mechanisms and Therapeutics (DMT), Genetics and Genomic Sciences [GGS]
Education
Master of Science, University of Rajasthan
PhD, University of Rajasthan
PostDoc, University of California Davis
Publications
Selected Publications
- Pregnancy as a Susceptible Period to Ambient Air Pollution Exposure on the Maternal Postpartum Metabolome. Sandra India Aldana, Lauren Petrick, Megan M. Niedzwiecki, Damaskini Valvi, Allan C. Just, Iván Gutiérrez-Avila, Itai Kloog, Dinesh K. Barupal, Martha María Téllez-Rojo, Robert O. Wright, Andrea A. Baccarelli, Haotian Wu, Elena Colicino. Environmental Science and Technology
- The need for a cancer exposome atlas: a scoping review. Anna S. Young, Catherine E. Mullins, Neha Sehgal, Roel C.H. Vermeulen, P. Martijn Kolijn, Jelle Vlaanderen, Mohammad L. Rahman, Brenda M. Birmann, Dinesh Barupal, Qing Lan, Nathaniel Rothman, Douglas I. Walker. JNCI Cancer Spectrum
- IARC Workshop on the Key Characteristics of Carcinogens: Assessment of End Points for Evaluating Mechanistic Evidence of Carcinogenic Hazards. David M. Demarini, William Gwinn, Emily Watkins, Brad Reisfeld, Weihsueh A. Chiu, Lauren Zeise, Dinesh Barupal, Parveen Bhatti, Kevin Cross, Eugenia Dogliotti, Jason M. Fritz, Dori Germolec, Maria Helena Guerra Andersen, Kathryn Z. Guyton, Jennifer Jinot, David H. Phillips, Roger R. Reddel, Nathaniel Rothman, Martin van den Berg, Roel C.H. Vermeulen, Paolo Vineis, Amy Wang, Maurice Whelan, Akram Ghantous, Michael Korenjak, Jiri Zavadil, Zdenko Herceg, Sandra Perdomo, Laure Dossus, Shirisha Chittiboyina, Danila Cuomo, John Kaldor, Elisa Pasqual, Gabrielle Rigutto, Roland Wedekind, Caterina Facchin, Fatiha El Ghissassi, Aline de Conti, Mary K. Schubauer-Berigan, Federica Madia. Environmental Health Perspectives