Publications:85
Donghoon Lee, PhD
About Me
Donghoon Lee is an Assistant Professor of the Department of Genetics and Genomic Sciences and the Department of Psychiatry at the Icahn School of Medicine at Mount Sinai. He currently serves as the Director of Single Cell Neurogenomics Group at the Center for Disease Neurogenomics (CDN).
His research is focused on computational psychiatric genomics. Leveraging the wealth of single-nucleus and functional genomic data, he is developing new methodologies for understanding the genetic basis of neuropsychiatric and neurodegenerative disorders.
Prior to joining the Icahn School of Medicine at Mount Sinai, Dr. Lee received his doctorate degree and postdoctoral training from Yale University.
Language
English
Position
ASSISTANT PROFESSOR | Genetics and Genomic Sciences, ASSISTANT PROFESSOR | Psychiatry
Research Topics
Alzheimer's Disease, Bioinformatics, Brain, Computational Biology, Epigenomics, Genetics, Genomics, Microglia, Neural Networks, Neuroscience, Psychiatry
Education
PhD, Yale University
Postdoc, Yale University
BS, Washington University
Publications
Selected Publications
- Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution. John F. Fullard, Prashant NM, Donghoon Lee, Deepika Mathur, Karen Therrien, Aram Hong, Clara Casey, Zhiping Shao, Marcela Alvia, Stathis Argyriou, Tereza Clarence, David Burstein, Sanan Venkatesh, Pavan K. Auluck, Lisa L. Barnes, David A. Bennett, Stefano Marenco, Biao Zeng, Hui Yang, Zhenyi Wu, Xinyi Wang, Daifeng Wang, Fotios Tsetsos, Karen Therrien, Collin Spencer, Maxim Signaevsky, Lyra Sheu, Madeline R. Scott, Genadi Ryan, Vivek G. Ramaswamy, Christian Porras, Milos Pjanic, Jennifer Monteiro Fortes, Colleen A. McClung, Nicolas Y. Masse, Athan Z. Li, Mikaela Koutrouli, Roman Kosoy, Steven P. Kleopoulos, Seon Kinrot, Saniya Khullar, Pavel Katsel, Ting Jin, Pengfei Dong, Kiran Girdhar, Vahram Haroutunian, Gabriel E. Hoffman, Georgios Voloudakis, Jaroslav Bendl, Panos Roussos. Scientific data
- Alzheimer’s disease transcriptional landscape in ex vivo human microglia. Roman Kosoy, John F. Fullard, Jaroslav Bendl, Steven P. Kleopoulos, Zhiping Shao, Stathis Argyriou, Deepika Mathur, Konstantina Psychogyiou, Periklis Malakates, James Vicari, Yixuan Ma, Jack Humphrey, Erica Brophy, Towfique Raj, Pavel Katsel, Georgios Voloudakis, Donghoon Lee, David A. Bennett, Vahram Haroutunian, Gabriel E. Hoffman, Panos Roussos. Nature Neuroscience
- A map of enhancer regions in primary human neural progenitor cells using capture STARR-seq. Sophia C. Gaynor-Gillett, Lijun Cheng, Manman Shi, Jason Liu, Gaoyuan Wang, Megan Spector, Qiuyu Guo, Le Qi, Mary Flaherty, Martha Wall, Ahyeon Hwang, Mengting Gu, Zhanlin Chen, Yuhang Chen, Jennifer R. Moran, Jing Zhang, Donghoon Lee, Mark Gerstein, Daniel H. Geschwind, Kevin P. White, Schahram Akbarian, Alexej Abyzov, Nadav Ahituv, Dhivya Arasappan, Jose Juan Almagro Armenteros, Brian J. Beliveau, Jaroslav Bendl, Sabina Berretta, Rahul A. Bharadwaj, Arjun Bhattacharya, Lucy Bicks, Kristen Brennand, Davide Capauto, Frances A. Champagne, Tanima Chatterjee, Chris Chatzinakos, Andrew Chess, Nikolaos P. Daskalakis, John F. Fullard, Kiran Girdhar, Vahram Haroutunian, Gabriel E. Hoffman, Alex Kozlenkov, Dalila Pinto, Towfique Raj, Panos Roussos, Robert Sebra, Harm van Bakel, Georgios Voloudakis, Biao Zeng. Genome Research