
Donghoon Lee, PhD
About Me
Donghoon Lee is an Assistant Professor of the Department of Genetics and Genomic Sciences and the Department of Psychiatry at the Icahn School of Medicine at Mount Sinai. He currently serves as the Director of Single Cell Neurogenomics Group at the Center for Disease Neurogenomics (CDN).
His research is focused on computational psychiatric genomics. Leveraging the wealth of single-nucleus and functional genomic data, he is developing new methodologies for understanding the genetic basis of neuropsychiatric and neurodegenerative disorders.
Prior to joining the Icahn School of Medicine at Mount Sinai, Dr. Lee received his doctorate degree and postdoctoral training from Yale University.
Language
English
Position
ASSISTANT PROFESSOR | Genetics and Genomic Sciences, ASSISTANT PROFESSOR | Psychiatry
Research Topics
Alzheimer's Disease, Bioinformatics, Brain, Computational Biology, Epigenomics, Genetics, Genomics, Microglia, Neural Networks, Neuroscience, Psychiatry
Education
PhD, Yale University
Postdoc, Yale University
BS, Washington University
Publications
Selected Publications
- Biological insights into schizophrenia from ancestrally diverse populations. Tim B. Bigdeli, Chris Chatzinakos, Jaroslav Bendl, Peter B. Barr, Sanan Venkatesh, Bryan R. Gorman, Tereza Clarence, Giulio Genovese, Conrad O. Iyegbe, Roseann E. Peterson, Sergios Orestis Kolokotronis, David Burstein, Jacquelyn L. Meyers, Yuli Li, Sundar Natarajan, Michael O. Francis, Nallakkandi Rajeevan, Kei Hoi Cheung, Lynn E. DeLisi, Thomas R. Kosten, Hongyu Zhao, Eric Achtyes, Peter F. Buckley, Dolores Malaspina, Douglas Lehrer, Mark H. Rapaport, David L. Braff, Michele T. Pato, Ayman H. Fanous, Carlos N. Pato, Grant D. Huang, Sumitra Muralidhar, J. Michael Gaziano, Saiju Pyarajan, Kiran Girdhar, Donghoon Lee, Gabriel E. Hoffman, Mihaela Aslan, John F. Fullard, Georgios Voloudakis, Philip D. Harvey, Panos Roussos. Nature
- Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution. John F. Fullard, Prashant NM, Donghoon Lee, Deepika Mathur, Karen Therrien, Aram Hong, Clara Casey, Zhiping Shao, Marcela Alvia, Stathis Argyriou, Tereza Clarence, David Burstein, Sanan Venkatesh, Pavan K. Auluck, Lisa L. Barnes, David A. Bennett, Stefano Marenco, Biao Zeng, Hui Yang, Zhenyi Wu, Xinyi Wang, Daifeng Wang, Fotios Tsetsos, Karen Therrien, Collin Spencer, Maxim Signaevsky, Lyra Sheu, Madeline R. Scott, Genadi Ryan, Vivek G. Ramaswamy, Christian Porras, Milos Pjanic, Jennifer Monteiro Fortes, Colleen A. McClung, Nicolas Y. Masse, Athan Z. Li, Mikaela Koutrouli, Roman Kosoy, Steven P. Kleopoulos, Seon Kinrot, Saniya Khullar, Pavel Katsel, Ting Jin, Pengfei Dong, Kiran Girdhar, Vahram Haroutunian, Gabriel E. Hoffman, Georgios Voloudakis, Jaroslav Bendl, Panos Roussos. Scientific data
- Alzheimer’s disease transcriptional landscape in ex vivo human microglia. Roman Kosoy, John F. Fullard, Jaroslav Bendl, Steven P. Kleopoulos, Zhiping Shao, Stathis Argyriou, Deepika Mathur, Konstantina Psychogyiou, Periklis Malakates, James Vicari, Yixuan Ma, Jack Humphrey, Erica Brophy, Towfique Raj, Pavel Katsel, Georgios Voloudakis, Donghoon Lee, David A. Bennett, Vahram Haroutunian, Gabriel E. Hoffman, Panos Roussos. Nature Neuroscience
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Lee has not yet completed reporting of Industry relationships.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.