Publications:96
Donghoon Lee, PhD
About Me
Donghoon Lee is an Assistant Professor of the Department of Genetics and Genomic Sciences and the Department of Psychiatry at the Icahn School of Medicine at Mount Sinai. He currently serves as the Director of Single Cell Neurogenomics Group at the Center for Disease Neurogenomics (CDN).
His research is focused on computational psychiatric genomics. Leveraging the wealth of single-nucleus and functional genomic data, he is developing new methodologies for understanding the genetic basis of neuropsychiatric and neurodegenerative disorders.
Prior to joining the Icahn School of Medicine at Mount Sinai, Dr. Lee received his doctorate degree and postdoctoral training from Yale University.
Language
English
Position
ASSISTANT PROFESSOR | Genetics and Genomic Sciences, ASSISTANT PROFESSOR | Psychiatry
Research Topics
Alzheimer's Disease, Bioinformatics, Brain, Computational Biology, Epigenomics, Genetics, Genomics, Microglia, Neural Networks, Neuroscience, Psychiatry
Education
PhD, Yale University
Postdoc, Yale University
BS, Washington University
Publications
Selected Publications
- Efficient differential expression analysis of large-scale single-cell transcriptomics data using Dreamlet. Gabriel E. Hoffman, Donghoon Lee, Jaroslav Bendl, N. M. Prashant, Aram Hong, Clara Casey, Marcela Alvia, Zhiping Shao, Stathis Argyriou, Karen Therrien, Sanan Venkatesh, Georgios Voloudakis, Vahram Haroutunian, John F. Fullard, Panos Roussos. Nature Communications
- SECmeres outperform extracellular vesicles as potential blood RNA biomarkers for Alzheimer’s disease. Edgar Gonzalez-Kozlova, Swapnil Tichkule, Yohei Nose, Tzu Yi Chen, Eduard Reznik, Juliet V. Santiago, Anish Korrapati, Taliah Soleymani, Roman Kosoy, Igor Figueiredo, Donghoon Lee, Gabriel E. Hoffman, Natasha Kyprianou, Ronald E. Gordon, Carlos Cordon-Cardo, Srikant Rangaraju, Nicholas T. Seyfried, Vahram Haroutunian, John F. Fullard, Panos Roussos, Navneet Dogra. Nature Communications
- Personalized single-cell transcriptomics reveals molecular diversity in Alzheimer's disease. Pramod Bharadwaj Chandrashekar, Sayali Anil Alatkar, Noah Cohen Kalafut, Ting Jin, Chirag Gupta, Ryan Conway Burczak, Xiang Huang, Shuang Liu, Athan Z. Li, Kiran Girdhar, Georgios Voloudakis, Gabriel E. Hoffman, Jaroslav Bendl, John F. Fullard, Donghoon Lee, Panos Roussos, Daifeng Wang. Nature communications
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Lee has not yet completed reporting of industry relationships or has no industry relationships to report.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.