
Eirini Papapetrou, MD, PhD
About Me
Eirini Papapetrou studies blood disorders, particularly myeloid malignancies, with human pluripotent stem cells. Her lab developed the first iPSC models of Myelodysplastic Syndromes and Acute Myeloid Leukemia. The Papapetrou lab combines expertise in induced pluripotent stem (iPS) cell generation, genome editing (CRISPR) and hematopoiesis.
Dr. Papapetrou is on Twitter at @PapapetrouMDPhD
Language
English
Position
PROFESSOR | Oncological Sciences, PROFESSOR | Medicine, Hematology and Medical Oncology
Research Topics
Cancer Genetics, Hematopoiesis, Stem Cells
Multi-Disciplinary Training Areas
Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS], Disease Mechanisms and Therapeutics (DMT)
Video
Education
MD, University of Patras, Greece
PhD, University of Patras, Greece
Postdoctoral, Memorial Sloan-Kettering Cancer Center
Awards
2021
American Association for Cancer Research (AACR)-MPM oncology charitable foundation transformative cancer research award
2018
Leukemia & Lymphoma Society (LLS) Scholar Award
2018
Elected member of the American Society for Clinical Investigation (ASCI)
2017
Pershing Square Sohn Prize
2016
Outstanding New Investigator Award
American Society of Gene and Cell Therapy (ASGCT)
2015
Tito Bastianello Young Investigator Award
MDS International Foundation
2014
American Society for Clinical Investigation Young Physician-Scientist Award
American Society for Clinical Investigation (ASCI)
2013
American Society of Hematology (ASH) Junior Faculty Scholar Award
American Society of Hematology (ASH)
2013
Sidney Kimmel Foundation Scholar Award
Sidney Kimmel Foundation for Cancer Research
2013
Aplastic Anemia & MDS IF Research Grant Award
Aplastic Anemia & MDS International Foundation
2013
John H. Tietze Stem Cell Scientist Award
2013
Ellison Medical Foundation New Scholar in Aging Award
Ellison Medical Foundation
2013
Damon Runyon-Rachleff Innovation Award
Damon Runyon Cancer Research Foundation
2013
UW Royalty Research Fund Award
University of Washington
2011
K99/R00 Pathway to Independence Award
NIH/NIDDK
Research
Publications
Selected Publications
- A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression. Ruba Almaghrabi, Yara Alyahyawi, Peter Keane, Syed A. Mian, Khadidja Habel, Amelia Atkinson, Carl Ward, Rachel Bayley, Claudia Sargas, Pablo Menendez, George J. Murphy, Turki Sobahy, Mohammed A. Baghdadi, Arwa F. Flemban, Saeed M. Kabrah, Raul Torres-Ruiz, Eirini P. Papapetrou, Ildem Akerman, Manoj Raghavan, Eva Barragan, Dominique Bonnet, Constanze Bonifer, Paloma Garcia. Nature Communications
- Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival. Monika Komza, Jesminara Khatun, Jesse D. Gelles, Andrew P. Trotta, Ioana Abraham-Enachescu, Juan Henao, Ahmed Elsaadi, Andriana G. Kotini, Cara Clementelli, Jo Ann Arandela, Sebastian El Ghaity-Beckley, Agneesh Barua, Yiyang Chen, Mirela Berisa, Bridget K. Marcellino, Eirini P. Papapetrou, Masha V. Poyurovsky, Jerry Edward Chipuk. Cell Communication and Signaling
- Natural killer cells’ functional impairment drives the immune escape of pre-malignant clones in early-stage myelodysplastic syndromes. Juan Jose Rodriguez-Sevilla, Irene Ganan-Gomez, Bijender Kumar, Natthakan Thongon, Feiyang Ma, Kelly S. Chien, Yi J. Kim, Hui Yang, Sanam Loghavi, Roselyn Tan, Vera Adema, Zongrui Li, Tomoyuki Tanaka, Hidetaka Uryu, Rashmi Kanagal-Shamanna, Gheath Al-Atrash, Rafael Bejar, Pinaki Prosad Banerjee, Sophia Lynn Cha, Guillermo Montalban-Bravo, Max Dougherty, Maria Claudina Fernandez Laurita, Noelle Wheeler, Baosen Jia, Eirini P. Papapetrou, Franco Izzo, Daniela E. Dueñas, Salome McAllen, Yiqian Gu, Gabriele Todisco, Francesca Ficara, Matteo Giovanni Della Porta, Abhinav Jain, Koichi Takahashi, Karen Clise-Dwyer, Stephanie Halene, Maria Teresa Sabrina Bertilaccio, Guillermo Garcia-Manero, May Daher, Simona Colla. Nature Communications