Publications:117
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Gregory A Elder, MD
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About Me
Language
Position
Research Topics
Aging, Alzheimer's Disease, Brain, Endothelial Cells, Neuro-degeneration/protection, Stem Cells
Multi-Disciplinary Training Areas
Neuroscience [NEU]
About Me
Language
Position
Research Topics
Aging, Alzheimer's Disease, Brain, Endothelial Cells, Neuro-degeneration/protection, Stem Cells
Multi-Disciplinary Training Areas
Neuroscience [NEU]
About Me
Language
Position
Research Topics
Aging, Alzheimer's Disease, Brain, Endothelial Cells, Neuro-degeneration/protection, Stem Cells
Multi-Disciplinary Training Areas
Neuroscience [NEU]
Education
BA, University of Illinois
Research
Research interests include Alzheimer's disease and related dementias, in particular how mutations in presenilin-1 cause familial Alzheimer's disease using transgenic mouse models. We also study the normal biological functions of the presenilin-1 gene using mouse models and cell culture.
Key words:
Alzheimer's disease
Presenilin-1
Familial Alzheimer's disease
Transgenic mice
Key words:
Alzheimer's disease
Presenilin-1
Familial Alzheimer's disease
Transgenic mice
Locations
Publications
Selected Publications
- Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures. Miguel A. Gama Sosa, Rita De Gasperi, Dylan Pryor, Georgina S. Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Seth Hogg, Benjamin Ache, Allison Sowa, Timothy Tetreault, Merina Varghese, David G. Cook, Carolyn W. Zhu, Susan J. Tappan, William G.M. Janssen, Patrick R. Hof, Stephen T. Ahlers, Gregory A. Elder. Acta neuropathologica communications
- Progressive Transcriptional Changes in the Amygdala Implicate Neuroinflammation in the Effects of Repetitive Low-Level Blast Exposure in Male Rats. Rita De Gasperi, Miguel A. Gama Sosa, Georgina S. Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Jonathan K. Statz, Jacob Patterson, Patrick R. Hof, Pavel Katsel, David G. Cook, Stephen T. Ahlers, Gregory A. Elder. Journal of Neurotrauma
- BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPT<sup>P301S</sup> mouse model of tauopathy. Georgina Perez-Garcia, Mesude Bicak, Jean Vianney Haure-Mirande, Gissel M. Perez, Alena Otero-Pagan, Miguel A. Gama Sosa, Rita De Gasperi, Mary Sano, Carrolee Barlow, Fred H. Gage, Benjamin Readhead, Michelle E. Ehrlich, Sam Gandy, Gregory A. Elder. Neuroscience Letters