Publications:49
Hideo Watanabe, MD, PhD
About Me
Language
English
Position
ASSOCIATE PROFESSOR | Medicine, Pulmonary, Critical Care and Sleep Medicine, ASSOCIATE PROFESSOR | Genetics and Genomic Sciences
Research Topics
Cancer, Cancer Genetics, Cellular Differentiation, Chromatin, Gene Regulation, Genomics, Lung, Molecular Biology
Multi-Disciplinary Training Areas
Cancer Biology [CAB]
Education
MD, Keio University School of Medicine
PhD, Keio University Graduate School of Medicine
, Broad Institute
, Dana-Farber Cancer Institute
Research
The Watanabe lab's primary interest is to understand the transcriptional programs of lung cancer. Our group uses functional genomics technologies including RNA sequencing and ChIP sequencing combined with single cell genome technologies to characterize lineage programs governing lung cancers. Keyword: Cancer, Cancer Genetics, Cellular Differentiation, Chromatin, Epigenetics, Gene Regulation, Genomics, Lung, Molecular Biology, Transcription Factors
Publications
Selected Publications
- EGFR-mutant transformed small cell lung cancer harbors intratumoral heterogeneity targetable with MEK inhibitor combination therapy. Atsuko Ogino, Amir Vajdi, Xinmeng Jasmine Mu, Navin R. Mahadevan, Kenneth Ngo, Matthew A. Booker, Paloma Cejas, Jeffrey J. Okoro, Man Xu, Benjamin F. Springer, Benjamin K. Eschle, Cameron M. Messier, Stephen Wang, Sudeepa Syamala, Rubii M. Tamen, Anika E. Adeni, Emily S. Chambers, Israel Canadas, Tran Thai, Camilla L. Christensen, Chunxiao Xu, Patrick H. Lizotte, Geoffrey R. Oxnard, Hideo Watanabe, Henry W. Long, Prafulla C. Gokhale, Cloud P. Paweletz, Lynette M. Sholl, Matthew G. Oser, David A. Barbie, Michael Y. Tolstorukov, Pasi A. Jänne. JCI insight
- Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells. Atsuho Morita, Makoto Ishii, Takanori Asakura, Masaya Yotsukura, Ahmed E. Hegab, Tatsuya Kusumoto, Ho Namkoong, Takunori Ogawa, Yuhki Nakatake, Mayumi Oda, Fumitake Saito, Hirofumi Kamata, Junko Hamamoto, Satoshi Okamori, Toshiki Ebisudani, Hiroyuki Yasuda, Shinya Sugimoto, Yuta Kuze, Masahide Seki, Yutaka Suzuki, Naoki Hasegawa, Hisao Asamura, Hideo Watanabe, Minoru Ko, Toshiro Sato, Masaki Ieda, Koichi Fukunaga. npj Regenerative Medicine
- Transcriptional regulatory network analysis identifies GRN as a key regulator bridging chemotherapy and immunotherapy response in small cell lung cancer. Seungyeul Yoo, Ayushi S. Patel, Sarah Karam, Yi Zhong, Li Wang, Feng Jiang, Ranran Kong, Sharon Bikvan, Wenhui Wang, Abhilasha Sinha, Charles A. Powell, Jun Zhu, Hideo Watanabe. Journal of Hematology and Oncology