Publications:46
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Accepting New PatientsHongyan Zou, MD, PhD
Neurosurgery
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About Me
Dr. Hongyan Zou focuses her clinical practice on minimally-invasive and complex spine surgery, brain and spine tumors, and general neurosurgery.
Read Dr. Zou's profile in Chinese
Dr. Zou's research laboratory studies axon regeneration and neurodevelopment, as well as brain tumor. Her research supports the development of novel treatments for neural repair and brain cancer.
Zou lab website
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Morningside
- Mount Sinai Brooklyn
- Mount Sinai Queens
- The Mount Sinai Hospital
- Mount Sinai West
Research Topics
Axon Guidance, Axonal Growth and Degeneration, Brain, Cancer Genetics, Developmental Neurobiology, Epigenetics, Neurobiology, Regeneration, Spinal Cord, Stem Cells, Transcription Factors, Tumorigenesis
Multi-Disciplinary Training Areas
Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS], Neuroscience [NEU]
About Me
Dr. Hongyan Zou focuses her clinical practice on minimally-invasive and complex spine surgery, brain and spine tumors, and general neurosurgery.
Read Dr. Zou's profile in Chinese
Dr. Zou's research laboratory studies axon regeneration and neurodevelopment, as well as brain tumor. Her research supports the development of novel treatments for neural repair and brain cancer.
Zou lab website
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Morningside
- Mount Sinai Brooklyn
- Mount Sinai Queens
- The Mount Sinai Hospital
- Mount Sinai West
Research Topics
Axon Guidance, Axonal Growth and Degeneration, Brain, Cancer Genetics, Developmental Neurobiology, Epigenetics, Neurobiology, Regeneration, Spinal Cord, Stem Cells, Transcription Factors, Tumorigenesis
Multi-Disciplinary Training Areas
Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS], Neuroscience [NEU]
Clinical Focus
- Acoustic Neuroma
- Acoustic Neuroma Removal
- Biopsy
- Bone Cancer
- Brain Tumor And Brain Cancer
- Brain, Spine Tumors
- Carpal Tunnel Release
- Carpal Tunnel Syndrome
- Cauda Equina Syndrome
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Education
MD, Stanford University School of Medicine
PhD, Cornell University and Memorial Sloan-Kettering Institute
Internship, Surgery (General Surgery)
Stanford University School of Medicine
Residency, Neurosurgery
Stanford University School of Medicine
Certifications
American Board of Neurological Surgery
Research
Specific Research Interests
- Molecular mechanisms of axon growth
- Transcription factors regulating axonal regeneration
- Neural stem cell proliferation, differentiation, and implication in CNS tumorigenesis
Our lab is interested in understanding how neurons are born, how they extend axons, and how they regenerate or fail to regenerate after injury. Brain and spinal cord injuries account for billions of dollars each year in medical costs. Understanding classic and identifying novel signaling pathways that promote neurogenesis and axonogenesis will provide new molecular targets towards effective CNS regeneration. Similar mechanisms that regulate the neural stem cell niche also regulate brain tumor stem cells. Understanding tumor microenvironment will have great impact on developing novel strategies to curb brain cancer invasion and relapse.
Zou lab website
- Molecular mechanisms of axon growth
- Transcription factors regulating axonal regeneration
- Neural stem cell proliferation, differentiation, and implication in CNS tumorigenesis
Our lab is interested in understanding how neurons are born, how they extend axons, and how they regenerate or fail to regenerate after injury. Brain and spinal cord injuries account for billions of dollars each year in medical costs. Understanding classic and identifying novel signaling pathways that promote neurogenesis and axonogenesis will provide new molecular targets towards effective CNS regeneration. Similar mechanisms that regulate the neural stem cell niche also regulate brain tumor stem cells. Understanding tumor microenvironment will have great impact on developing novel strategies to curb brain cancer invasion and relapse.
Zou lab website
Locations
Insurance Information
Accepted insurance may vary by the doctor’s office location. Please contact the office directly to obtain the most up-to-date insurance information.
Patients with Cigna Medicare Advantage or Humana Medicare Advantage insurance: Please read this important message before booking to find out if out-of-network costs may apply to your next visit.
- Mount Sinai Doctors Faculty Practice5 East 98th Street, 7th Floor, New York, NY, 10029
- Mount Sinai Doctors-168 Centre Street168 Centre Street, Suite 3M, New York, NY, 10013
- Mount Sinai Doctors-Flushing135-16 Roosevelt Avenue, Second Floor, Flushing, NY, 11354
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.
Publications
Selected Publications
- Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2. Chrystian Junqueira Alves, Theodore Hannah, Sita Sadia, Christy Kolsteeg, Angela Dixon, Robert J. Wiener, Ha Nguyen, Murray J. Tipping, Júlia Silva Ladeira, Paula Fernandes da Costa Franklin, Nathália de Paula Dutra de Nigro, Rodrigo Alves Dias, Priscila V. Zabala Capriles, José P. Rodrigues Furtado de Mendonça, Paul A. Slesinger, Kevin D. Costa, Hongyan Zou, Roland H. Friedel. Nature Communications
- Glioblastoma shift from bulk to infiltrative growth is guided by plexin-B2-mediated microglia alignment in invasive niches. Sangjo Kang, Mary E. Ughetta, Jack Y. Zhang, Valerie J. Marallano, Anirudh Sattiraju, Theodore Hannah, Shalaka Wahane, Aarthi Ramakrishnan, Molly Estill, Nadejda M. Tsankova, Li Shen, Alexander M. Tsankov, Roland H. Friedel, Hongyan Zou. Nature Cancer
- Hypoxia drives shared and distinct transcriptomic changes in two invasive glioma stem cell lines. Valerie J. Marallano, Mary E. Ughetta, Rut Tejero, Sidhanta Nanda, Rohana Ramalingam, Lauren Stalbow, Anirudh Sattiraju, Yong Huang, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Hongyan Zou, Alexander M. Tsankov, Roland H. Friedel. Scientific Reports
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Zou did not report having any of the following types of financial relationships with industry and other outside entities during 2024 and/or 2025: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Zou did not report having any of the following types of financial relationships with industry and other outside entities during 2024 and/or 2025: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.