Publications:185
Honoratus Van Bakel, PhD
About Me
Harm van Bakel's research is focused on applying novel genomics technologies to fundamental problems in infectious disease to understand host:pathogen interactions and the molecular basis of evolution and transmission of bacteria and viruses. His lab further applies the latest bulk-tissue, single-cell and spatial transcriptomics technologies to characterize host responses to infection/vaccination. He also uses the same transcriptomic technologies to study craniofacial development, revealing the cell types and gene-regulatory networks that govern suture development and craniosynostosis.
Language
English
Position
ASSOCIATE PROFESSOR | Genetics and Genomic Sciences, ASSOCIATE PROFESSOR | Microbiology, ASSOCIATE PROFESSOR | Artificial Intelligence and Human Health
Research Topics
Antimicrobial Resistance, Bacterial Genetics, Bioinformatics, Coronavirus, Gene Regulation, Genomics, Infectious Disease, Influenza Virus, RNA, RNA Splicing & Processing, SARS Virus, Sequence Alignment, Staphylococcus Aureus, Stem Cells, Virulence Genes, Viruses and Virology
Multi-Disciplinary Training Areas
Genetics and Genomic Sciences [GGS], Microbiology [MIC]
Video
Education
MS, University of Utrecht
PhD, University of Utrecht
Research
Publications
Selected Publications
- Cross-species and mammal-to-mammal transmission of clade 2.3.4.4b highly pathogenic avian influenza A/H5N1 with PB2 adaptations. Catalina Pardo-Roa, Martha I. Nelson, Naomi Ariyama, Carolina Aguayo, Leonardo I. Almonacid, Ana S. Gonzalez-Reiche, Gabriela Muñoz, Mauricio Ulloa, Claudia Ávila, Carlos Navarro, Rodolfo Reyes, Pablo N. Castillo-Torres, Christian Mathieu, Ricardo Vergara, Álvaro González, Carmen Gloria González, Hugo Araya, Andrés Castillo, Juan Carlos Torres, Paulo Covarrubias, Patricia Bustos, Harm van Bakel, Jorge Fernández, Rodrigo A. Fasce, Magdalena Johow, Víctor Neira, Rafael A. Medina. Nature Communications
- Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients. Harry Pickering, Joanna Schaenman, Hoang Van Phan, Cole Maguire, Alexandra Tsitsiklis, Nadine Rouphael, Nelson Iván Agudelo Higuita, Mark A. Atkinson, Scott Brakenridge, Monica Fung, William Messer, Vicki Seyfert-Margolis, Adeeb Rahman, Kari Wong, Greg Michelotti, Scott R. Hutton, James A. Overton, Crystal Nagle, Judie Sheidy, Pam Schearer, Kristen Ulring, Nathan Mege, Brandon Rogowski, George P. Tegos, Renee McLin, Sara Furukawa, Mathew R. Bell, Nicholas C. Semenza, Brett Croen, Mark Martens, Cecilia M. Smith, Brent Simmons, I. Michael Goonewardene, Kai Nie, Manishkumar Patel, Hui Xie, Daniel Stadlbauer, Giulio Kleiner, Erna Kojic, Deena Altman, Miti Saksena, Lubbertus C.F. Mulder, Geoffrey Kelly, Brian Lee, Jingjing Qi, Ana Silvia Gonzalez-Reiche, Harm Van Bakel, Viviana Simon, Seunghee Kim-Schulze, Florian Krammer. Nature Communications
- Mutation T9I in Envelope confers autophagy resistance to SARS-CoV-2 Omicron. Susanne Klute, Rayhane Nchioua, Arne Cordsmeier, Jyoti Vishwakarma, Lennart Koepke, Hala Alshammary, Christoph Jung, Maximilian Hirschenberger, Helene Hoenigsperger, Jana Romana Fischer, Rinu Sivarajan, Fabian Zech, Steffen Stenger, Ruth Serra-Moreno, Ana Silvia Gonzalez-Reiche, Emilia Mia Sordillo, Harm van Bakel, Viviana Simon, Frank Kirchhoff, Timo Jacob, Dorota Kmiec, Andreas Pichlmair, Armin Ensser, Konstantin Maria Johannes Sparrer. iScience