
Ian S Maze, PhD
About Me
Ian S. Maze, Ph.D., is a chromatin biologist and neuroscientist investigating the complex interplay between chromatin regulatory mechanisms and neural plasticity in the mammalian central nervous system. His multidisciplinary and integrative research involves the use of biochemical, biophysical, physiological and behavioral analyses to explore the molecular underpinnings of neurodevelopmental and adult cognitive and psychiatric disorders. Dr. Maze is actively investigating the brains of rodents and postmortem humans, as well as human iPSC-derived neurons, to uncover chromatin-based mechanisms of neurological disease.
Language
Position
Research Topics
Addiction, Behavior, Chromatin, Depression, Drug Design and Discovery, Gene Expressions, Molecular Biology, Neuroscience
Multi-Disciplinary Training Areas
Disease Mechanisms and Therapeutics (DMT), Neuroscience [NEU]
About Me
Ian S. Maze, Ph.D., is a chromatin biologist and neuroscientist investigating the complex interplay between chromatin regulatory mechanisms and neural plasticity in the mammalian central nervous system. His multidisciplinary and integrative research involves the use of biochemical, biophysical, physiological and behavioral analyses to explore the molecular underpinnings of neurodevelopmental and adult cognitive and psychiatric disorders. Dr. Maze is actively investigating the brains of rodents and postmortem humans, as well as human iPSC-derived neurons, to uncover chromatin-based mechanisms of neurological disease.
Language
Position
Research Topics
Addiction, Behavior, Chromatin, Depression, Drug Design and Discovery, Gene Expressions, Molecular Biology, Neuroscience
Multi-Disciplinary Training Areas
Disease Mechanisms and Therapeutics (DMT), Neuroscience [NEU]
Video
Education
BS, The Ohio State University
PhD, Mount Sinai School of Medicine
Postdoctoral Fellowship, The Rockefeller University
Awards
2022
McKnight Brain Disorder Award
2021
Howard Hughes Medical Institute Investigator
2019
Dr. Harold and Golden Laport Basic Research Award
2019
Winner of Presidential Early Career Award for Scientists and Engineers (PECASE)
2017
Basil O’Connor Award
March of Dimes
2016
Sloan Foundation Fellowship in Neuroscience
2015
ACNP Travel Award
2015
MQ: Transforming Mental Health Research Fellowship Award
2014
NARSAD Young Investigator Award
2011
Terry A. Krulwich Dissertation Award, Mount Sinai School of Medicine
Research
Locations
Publications
Selected Publications
- Elucidating neuroepigenetic mechanisms to inform targeted therapeutics for brain disorders. Benjamin H. Weekley, Newaz I. Ahmed, Ian Maze. iScience
- A Novel Role for the Histone Demethylase JMJD3 in Mediating Heroin-Induced Relapse-Like Behaviors. Swarup Mitra, Craig T. Werner, Treefa Shwani, Ana Garcia Lopez, Dale Federico, Kate Higdon, Xiaofang Li, Pedro H. Gobira, Shruthi A. Thomas, Jennifer A. Martin, Chunna An, Ramesh Chandra, Ian Maze, Rachel Neve, Mary Kay Lobo, Amy M. Gancarz, David M. Dietz. Biological Psychiatry
- Bidirectional histone monoaminylation dynamics regulate neural rhythmicity. Qingfei Zheng, Benjamin H. Weekley, David A. Vinson, Shuai Zhao, Ryan M. Bastle, Robert E. Thompson, Stephanie Stransky, Aarthi Ramakrishnan, Ashley M. Cunningham, Sohini Dutta, Jennifer C. Chan, Giuseppina Di Salvo, Min Chen, Nan Zhang, Jinghua Wu, Sasha L. Fulton, Lingchun Kong, Haifeng Wang, Baichao Zhang, Lauren Vostal, Akhil Upad, Lauren Dierdorff, Li Shen, Henrik Molina, Simone Sidoli, Tom W. Muir, Haitao Li, Yael David, Ian Maze. Nature