
Ilse S Daehn, PhD
About Me
Dr. Daehn research laboratory investigates the cell-type specific responses and signals of glomerular disease progression in CKD. With particular focus in examing the signaling crosstalk between podocytes, endocapillary cells and mesangial cells that lead to irreversible segmental sclerosis characteristic of glomerular disease progression. The research aims to identify novel glomerular lesion-specific therapeutic targets.
Dr. Daehn holds a degree in Biotechnology (Honors) from Flinders University of South Australia. She performed a research placement at the Fundacion Jimenez Diaz, Madrid before starting her Doctorate studies at Flinders University of SA, and was awarded her PhD in 2007. She was a postdoctoral fellow at Cancer Research UK, in London and came to NYC to pursue a second postdoctoral fellowship at Mount Sinai.
Dr. Daehn is a member of DBRC and OAEM Steering Committees and former Co-chair of the Postdoc Executive Committee at Mount Sinai. She sits on NYC Tech Connect’s Entrepreneurial Scientist Advisory Panel.
Please visit her lab website at http://labs.icahn.mssm.edu/daehnlab/.
Language
Position
Research Topics
Cell Biology, Kidney, Mitochondria, Oxidative Stress
Multi-Disciplinary Training Areas
Disease Mechanisms and Therapeutics (DMT)
About Me
Dr. Daehn research laboratory investigates the cell-type specific responses and signals of glomerular disease progression in CKD. With particular focus in examing the signaling crosstalk between podocytes, endocapillary cells and mesangial cells that lead to irreversible segmental sclerosis characteristic of glomerular disease progression. The research aims to identify novel glomerular lesion-specific therapeutic targets.
Dr. Daehn holds a degree in Biotechnology (Honors) from Flinders University of South Australia. She performed a research placement at the Fundacion Jimenez Diaz, Madrid before starting her Doctorate studies at Flinders University of SA, and was awarded her PhD in 2007. She was a postdoctoral fellow at Cancer Research UK, in London and came to NYC to pursue a second postdoctoral fellowship at Mount Sinai.
Dr. Daehn is a member of DBRC and OAEM Steering Committees and former Co-chair of the Postdoc Executive Committee at Mount Sinai. She sits on NYC Tech Connect’s Entrepreneurial Scientist Advisory Panel.
Please visit her lab website at http://labs.icahn.mssm.edu/daehnlab/.
Language
Position
Research Topics
Cell Biology, Kidney, Mitochondria, Oxidative Stress
Multi-Disciplinary Training Areas
Disease Mechanisms and Therapeutics (DMT)
Education
Bachelors, Flinders University
PhD, Flinders University
Awards
2019
NIDDK Basic Science Research Award
NMRI 17th Annual Workshop, Bethesda, MD
2017
Early Career Investigator Award Keystone Symposia
"Mitochondria Communications," Taos, NM
2016
4D Award - Pilot Project Grant
National Center for Advancing Translational Science
2015
Young Investigator Grant
National Kidney Foundation
2015
Quod Erat Demonstrandum (QED) Special Recognition Award
Icahn School of Medicine at Mount Siani
Research
My research focuses on exploring the complexity of signaling crosstalk between cells in the kidney. Particularly, my work aims to examine molecular mechanisms in the glomerulus that result in kidney disease progression and diabetic nephropathy in order to identify novel glomerular lesion-specific therapeutic targets and biomarkers. I have so far taken innovative approaches to examine the development of glomerular disease and the outcomes from this work have provided a fundamental paradigm shift in our current understanding of chronic kidney disease development.
Locations
Publications
Selected Publications
- Lived experience is essential for innovation in biomedical research. Jonathan Haydak, Jacob Wright, Paula L. Croxson, Ilse S. Daehn. Nature Reviews Nephrology
- Defining Kidney Health Dimensions and Their Associations with Adverse Outcomes in Persons with Diabetes and CKD. Vanessa Giselle Peschard, Rebecca Scherzer, Michelle M. Estrella, Mark J. Sarnak, Simon B. Ascher, James Lash, Joseph V. Bonventre, Jason H. Greenberg, Orlando M. Gutierrez, Jeffrey R. Schelling, Ronit Katz, Katharine L. Cheung, Emily B. Levitan, Sarah J. Schrauben, Mary Cushman, Titilayo O. Ilori, Chirag R. Parikh, Paul L. Kimmel, Panduranga S. Rao, Jonathan J. Taliercio, James Sondheimer, Rachel Shulman, Steven G. Coca, Jing Chen, Vasan S. Ramachandran, Joachim H. Ix, Michael G. Shlipak, Joseph Massaro, Clary Clish, Jeffrey Schelling, Tom Hostetter, Michelle Denburg, Susan Furth, Bradley Warady, Joseph Bonventre, Sushrut Waikar, Gearoid McMahon, Venkata Sabbisetti, Josef Coresh, Morgan Grams, Casey Rebholz, Alison Abraham, Adriene Tin, Jon Klein, Steven Coca, Bart S. Ferket, Girish N. Nadkarni, Eugene Rhee, Erwin Bottinger, Ilse Daehn. Clinical Journal of the American Society of Nephrology
- Induction of plasmalemmal vesicle-associated protein exacerbates glomerular endothelial injury in thrombotic microangiopathy. Chelsea C. Estrada, Craig Wilson, Nehaben Gujarati, Sumaya Ahmed, Robert Bronstein, Ilse S. Daehn, Monica P. Revelo, Yiqing Guo, Sandeep K. Mallipattu. American Journal of Physiology - Renal Physiology