Publications:39
Ivan Marazzi, PhD
About Me
The Marazzi lab studies epigenetic- and chromatin- mediated control of gene expression in the context of cellular response to pathogens or cellular differentiation. We are interested in proteins and non-coding RNA that play a role in controlling cell response and cell fate. We use biochemistry and next generation sequencing technique to understand molecular mechanisms and genome-wide effects of known and novel candidate genes.
Language
English
Position
ADJUNCT ASSOCIATE PROFESSOR | Microbiology
Research Topics
Epigenetics, Inflammation
Multi-Disciplinary Training Areas
Microbiology [MIC]
Education
PhD, Institute Research Biomedicine
Postdoctoral, Rockefeller University
Publications
Selected Publications
- ATM and IRAK1 orchestrate two distinct mechanisms of NF-κB activation in response to DNA damage. Elodie Bournique, Ambrocio Sanchez, Sunwoo Oh, Daniel Ghazarian, Alisa L. Mahieu, Lavanya Manjunath, Eirene Ednacot, Pedro Ortega, Selma Masri, Ivan Marazzi, Rémi Buisson. Nature Structural and Molecular Biology
- Circadian control of tumor immunosuppression affects efficacy of immune checkpoint blockade. Bridget M. Fortin, Shannon M. Pfeiffer, Jacob Insua-Rodríguez, Hamad Alshetaiwi, Alexander Moshensky, Wei A. Song, Alisa L. Mahieu, Sung Kook Chun, Amber N. Lewis, Alex Hsu, Isam Adam, Oliver S. Eng, Nicholas R. Pannunzio, Marcus M. Seldin, Ivan Marazzi, Francesco Marangoni, Devon A. Lawson, Kai Kessenbrock, Selma Masri. Nature Immunology
- A PRMT5-ZNF326 axis mediates innate immune activation upon replication stress. Phuong Mai Hoang, Denis Torre, Patrick Jaynes, Jessica Ho, Kevin Mohammed, Erik Alvstad, Wan Yee Lam, Vartika Khanchandani, Jie Min Lee, Chin Min Clarissa Toh, Rui Xue Lee, Akshaya Anbuselvan, Sukchan Lee, Robert P. Sebra, Martin J. Walsh, Ivan Marazzi, Dennis Kappei, Ernesto Guccione, Anand D. Jeyasekharan. Science advances
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Marazzi has not yet completed reporting of Industry relationships.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.