Publications:31
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Ivan Marazzi, PhD
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About Me
The Marazzi lab studies epigenetic- and chromatin- mediated control of gene expression in the context of cellular response to pathogens or cellular differentiation. We are interested in proteins and non-coding RNA that play a role in controlling cell response and cell fate. We use biochemistry and next generation sequencing technique to understand molecular mechanisms and genome-wide effects of known and novel candidate genes.
Language
Position
Research Topics
Epigenetics, Inflammation
Multi-Disciplinary Training Areas
Microbiology [MIC]
About Me
The Marazzi lab studies epigenetic- and chromatin- mediated control of gene expression in the context of cellular response to pathogens or cellular differentiation. We are interested in proteins and non-coding RNA that play a role in controlling cell response and cell fate. We use biochemistry and next generation sequencing technique to understand molecular mechanisms and genome-wide effects of known and novel candidate genes.
Language
Position
Research Topics
Epigenetics, Inflammation
Multi-Disciplinary Training Areas
Microbiology [MIC]
About Me
The Marazzi lab studies epigenetic- and chromatin- mediated control of gene expression in the context of cellular response to pathogens or cellular differentiation. We are interested in proteins and non-coding RNA that play a role in controlling cell response and cell fate. We use biochemistry and next generation sequencing technique to understand molecular mechanisms and genome-wide effects of known and novel candidate genes.
Language
Position
Research Topics
Epigenetics, Inflammation
Multi-Disciplinary Training Areas
Microbiology [MIC]
Education
PhD, Institute Research Biomedicine
Postdoctoral, Rockefeller University
Locations
Publications
Selected Publications
- Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics. Nan Zhao, Jessica Sook Yuin Ho, Simin Zheng, Lu Tian, H. Ümit Kaniskan, Ya Wen Chen, Jeffrey R. Johnson, Jian Jin, Ivan Marazzi. Cell Host and Microbe
- WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma. Alex Rialdi, Mary Duffy, Alex P. Scopton, Frank Fonseca, Julia Nanyi Zhao, Megan Schwarz, Pedro Molina-Sanchez, Slim Mzoughi, Elisa Arceci, Jordi Abril-Fornaguera, Austin Meadows, Marina Ruiz de Galarreta, Denis Torre, Kyna Reyes, Yan Ting Lim, Felix Rosemann, Zaigham M. Khan, Kevin Mohammed, Xuedi Wang, Xufen Yu, Manikandan Lakshmanan, Ravisankar Rajarethinam, Soo Yong Tan, Jian Jin, Augusto Villanueva, Eleftherios Michailidis, Ype P. De Jong, Charles M. Rice, Ivan Marazzi, Dan Hasson, Josep M. Llovet, Radoslaw M. Sobota, Amaia Lujambio, Ernesto Guccione, Arvin C. Dar. Nature Cancer
- Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR. Megan Schwarz, Denis Torre, Daniel Lozano-Ojalvo, Jessica S.Y. Ho, William M. Marsiglia, Arvin C. Dar, Cecilia Berin, Kai Nie, Manishkumar Patel, Sacha Gnjatic, Jocelyn Harris, Robert Sebra, Miriam Merad, Florian Krammer, Seunghee Kim-schulze, Ivan Marazzi, Jordi Ochando, Ernesto Guccione. Nature Biotechnology
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Marazzi during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting:
- Almston
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.