Publications:227
James C Iatridis, PhD
About Me
Dr. Iatridis is Professor and Vice Chair for Research in the Leni and Peter W. May Department of Orthopaedics at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Iatridis joined Mount Sinai in 2010 to drive his spine research in translational directions. Dr. Iatridis is Vice Chair for Reseach of Orthopaedics and the Director of the Spine Research Program of the Mount Sinai Health System. Dr. Iatridis graduated from Franklin and Marshall College with a B.A. in Physics, and then completed his B.S., M.S. and Ph.D. from Columbia University in Mechanical Engineering. He spent nearly 15 years at University of Vermont as post-doc and then faculty member in the School of Engineering (Mechanical & Biomedical Engineering) with secondary appointment in the Department of Orthopaedics.
For more information, please see Iatridis Lab and Orthopaedic Research Lab pages.
Language
English
Position
PROFESSOR | Orthopedics, PROFESSOR | Neurosurgery
Research Topics
Biomechanics/Bioengineering, Developmental Biology, Inflammation, Mathematical Modeling of Biomedical Systems, Orthopaedics, Pharmacology, Regeneration, Spinal Cord, Tissue Engineering, Translation
Multi-Disciplinary Training Areas
Artificial Intelligence and Emerging Technologies in Medicine [AIET], Development Regeneration and Stem Cells [DRS], Disease Mechanisms and Therapeutics (DMT), Neuroscience [NEU]
Education
BA, Franklin and Marshall College
PhD, Columbia University
Post-doctoral Fellowship, University of Vermont
Awards
2015
Henry Farfan Award
North American Spine Society
2009
Berton Rahn Research Prize
AO Research Fund,
2008
Presidential Early Career Award for Scientists and Engineers (PECASE)
United States of America
2001
Macnab LaRocca Fellowship
International Society for the Study of the Lumbar Spine
Research
Our laboratory is interested in investigations of functional changes in the spine in response to loading and injury, and investigations of promising therapeutic techniques to promote spine health and repair. Our investigations span biomechanics, mechanobiology, tissue engineering, anti-inflammatory and cellular therapies. Through our animal, cell, and organ culture studies we have a focus on models of injury and repair with high relevance to human clinical conditions. Our research balances exploration of fundamental mechanisms and translation with appreciation for the development and maturation processes in human joints that promote health and disease processes.
Publications
Selected Publications
- TNFR1-mediated senescence and lack of TNFR2-signaling limit human intervertebral disc cell repair potential in degenerative conditions. Jennifer Gansau, Elena Grossi, Levon Rodriguez, Minghui Wang, Damien M. Laudier, Saad Chaudhary, Andrew C. Hecht, Wenyu Fu, Robert Sebra, Chuan Ju Liu, James C. Iatridis. Osteoarthritis and Cartilage
- TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model. Timothy D. Jacobsen, S. Olga Yiantsos, Jennifer Gansau, James Meyers, Damien Laudier, James C. Iatridis. JOR Spine
- The Oswestry Disability Index and 12-Item Short Form Health Survey Physical Component Scores Are Not Affected by Recall Bias in Posterior Lumbar Spine Surgery Patients: A Prospective Study Using Data From Fitness Trackers. Justin Tiao, Ashley M. Rosenberg, Dennis M. Bienstock, Brittany Sacks, Charles Laurore, Michael Herrera, Dhruv S. Shankar, Wesley H. Bronson, Saad B. Chaudhary, Jashvant Poeran, James C. Iatridis, Andrew C. Hecht. Journal of the American Academy of Orthopaedic Surgeons Global Research and Reviews