
James Murrough, MD, PhD
Psychiatry
About Me
Dr. James Murrough is Professor of Psychiatry and Neuroscience and Director of the Depression and Anxiety Center for Discovery and Treatment at the Icahn School of Medicine at Mount Sinai. He is a Faculty member of the Friedman Brain Institute and a Primary Principal Investigator of the Center of Excellence in Neuropharmacology, both components of the Icahn School of Medicine. Dr. Murrough conducts clinical and translational research aimed at understanding the biological basis of mood and anxiety disorders in order to point the way towards new, more effective treatments. He received his Bachelor of Science in Neuroscience and Behavioral Biology from Emory University in Atlanta and his Medical degree from Tufts University School of Medicine in Boston. He completed his residency training in Psychiatry at Mount Sinai and a research fellowship in experimental therapeutics and clinical neuroscience in mood disorders, also at Mount Sinai. He obtained a PhD in clinical research methodology and biostatistics from Mount Sinai as part of a Career Development Award from the National Institute of Mental Health. Dr. Murrough has received research support from the National Institutes of Health, the Doris Duke Charitable Foundation, the American Foundation for Suicide Prevention, the Dana Foundation and the Brain and Behavior Research Foundation. He is a Member of the American College of Neuropsychopharmacology and an active member of the scientific community. In addition to his research and educational activities, Dr. Murrough maintains an active clinical practice focusing on evidence-based pharmacological treatments for mood and anxiety disorders.
Key Words: depression, anxiety, bipolar disorder, post traumatic stress disorder, psychopharmacology, antidepressants, neuroimaging
Financial & Billing Information
Please direct any detailed billing or financial inquires to the Mount Sinai Psychiatry billing customer service number at 212-659-8752.
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Morningside
- Mount Sinai Brooklyn
- Mount Sinai Queens
- The Mount Sinai Hospital
- Mount Sinai West
Research Topics
Depression, Neuropeptides, Neurophysiology, Neuroscience, Neurotransmitters, Neurotrophins, Patient Centered Outcomes Research, Psychiatry, Stress, Trauma
Multi-Disciplinary Training Areas
Neuroscience [NEU]
About Me
Dr. James Murrough is Professor of Psychiatry and Neuroscience and Director of the Depression and Anxiety Center for Discovery and Treatment at the Icahn School of Medicine at Mount Sinai. He is a Faculty member of the Friedman Brain Institute and a Primary Principal Investigator of the Center of Excellence in Neuropharmacology, both components of the Icahn School of Medicine. Dr. Murrough conducts clinical and translational research aimed at understanding the biological basis of mood and anxiety disorders in order to point the way towards new, more effective treatments. He received his Bachelor of Science in Neuroscience and Behavioral Biology from Emory University in Atlanta and his Medical degree from Tufts University School of Medicine in Boston. He completed his residency training in Psychiatry at Mount Sinai and a research fellowship in experimental therapeutics and clinical neuroscience in mood disorders, also at Mount Sinai. He obtained a PhD in clinical research methodology and biostatistics from Mount Sinai as part of a Career Development Award from the National Institute of Mental Health. Dr. Murrough has received research support from the National Institutes of Health, the Doris Duke Charitable Foundation, the American Foundation for Suicide Prevention, the Dana Foundation and the Brain and Behavior Research Foundation. He is a Member of the American College of Neuropsychopharmacology and an active member of the scientific community. In addition to his research and educational activities, Dr. Murrough maintains an active clinical practice focusing on evidence-based pharmacological treatments for mood and anxiety disorders.
Key Words: depression, anxiety, bipolar disorder, post traumatic stress disorder, psychopharmacology, antidepressants, neuroimaging
Financial & Billing Information
Please direct any detailed billing or financial inquires to the Mount Sinai Psychiatry billing customer service number at 212-659-8752.
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Morningside
- Mount Sinai Brooklyn
- Mount Sinai Queens
- The Mount Sinai Hospital
- Mount Sinai West
Research Topics
Depression, Neuropeptides, Neurophysiology, Neuroscience, Neurotransmitters, Neurotrophins, Patient Centered Outcomes Research, Psychiatry, Stress, Trauma
Multi-Disciplinary Training Areas
Neuroscience [NEU]
Clinical Focus
- Anxiety
- Depression
- Panic Disorder
- Post-Traumatic Stress Disorder
- Social Anxiety Disorder
Video
Education
MD, Tufts University School of Medicine
Residency, Psychiatry
Mount Sinai Hospital
Locations
Insurance Information
Accepted insurance may vary by the doctor’s office location. Please contact the office directly to obtain the most up-to-date insurance information.
Patients with Cigna Medicare Advantage or Humana Medicare Advantage insurance: Please read this important message before booking to find out if out-of-network costs may apply to your next visit.
- Physician OfficeOne Gustave L. Levy Place, Box 1230, NEW YORK, NY, 10029
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.
Publications
Selected Publications
- Patient preference effects in a randomized comparative effectiveness study of electroconvulsive therapy and ketamine for treatment resistant depression: An ELEKT-D trial secondary analysis. Gerard Sanacora, Brian S. Barnett, Bo Hu, Fernando S. Goes, Sanjay J. Mathew, James W. Murrough, Irving Reti, Samuel T. Wilkinson, Amit Anand. Psychiatry Research
- Cross-species dissection of the modular role of the ventral tegmental area in depressive disorders. L. S. Morris, J. M. Beltrán, J. W. Murrough, C. Morel. Neuroscience
- The genetics of severe depression. Clio E. Franklin, Eric Achtyes, Murat Altinay, Kala Bailey, Mahendra T. Bhati, Brent R. Carr, Susan K. Conroy, Mustafa M. Husain, Khurshid A. Khurshid, Todd Lencz, William M. McDonald, Brian J. Mickey, James Murrough, Sean Nestor, Thomas Nickl-Jockschat, Sina Nikayin, Kevin Reeves, Irving M. Reti, Salih Selek, Gerard Sanacora, Nicholas T. Trapp, Biju Viswanath, Jesse H. Wright, Patrick Sullivan, Peter P. Zandi, James B. Potash. Molecular Psychiatry
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Below are financial relationships with industry reported by Dr. Murrough during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- Autobahn Therapeutics
- Otsuka America Pharmaceuticals
- Frontier Pharma LLC
- National Institutes Of Health/DHHS
- Dr Jay
- Janssen Pharmaceuticals
- WCG Clinical, Inc.
Editorial Services
- International Journal of Neuropsychopharmacology
Outside Employment
- Department of Veterans Affairs
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Below are financial relationships with industry reported by Dr. Murrough during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- Autobahn Therapeutics
- Otsuka America Pharmaceuticals
- Frontier Pharma LLC
- National Institutes Of Health/DHHS
- Dr Jay
- Janssen Pharmaceuticals
- WCG Clinical, Inc.
Editorial Services
- International Journal of Neuropsychopharmacology
Outside Employment
- Department of Veterans Affairs
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.