Jens Hansen, PhD

Dr. Hansen’s research focuses on the cell biology of multiple diseases and developmental changes. He has built the Molecular Biology of the Cell Ontology, a strictly cell biological ontology, that he uses to identify relevant subcellular processes (www.mbc-ontology.org). His research approaches employ dynamic models of pathway activities to identify how such subcellular processes interact with each other to generate a whole cell response. He developed a novel drug repurposing approach that counter-regulates disease-relevant pathway activities, independently of the genes involved. Dr. Hansen uses graph theoretical methods to relate differentially expressed genes and other experimental data to prior knowledge. His research topics include neurite outgrowth, aortic aneurysm development and progression, kidney physiology and pathophysiology as well as drug-induced cardiomyopathies. For more information please jhansenlab.org.