Publications:27
- Mount Sinai Doctors
Jessica L Ables, MD, PhD
JESSICA LYNN ABLES (Preferred Name)
Psychiatry
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About Me
Dr. Jessica Ables is an Assistant Professor of Psychiatry and Neuroscience at the Icahn School of Medicine at Mount Sinai, a New York State licensed physician and an ABPN board-certified psychiatrist. Dr. Ables completed her undergraduate education in Chemistry at Southwestern University in Georgetown, TX. She then entered the Medical Scientist Training Program at UT Southwestern Medical Center in Dallas, where she completed her PhD in Integrative Biology. She then transferred to Mount Sinai to complete her medical schooling, graduating. After medical school, Dr. Ables went to The Rockefeller University for a 4 year postdoctoral fellowship in molecular Neuroscience prior to returning to Mount Sinai to complete her residency training in Psychiatry.
Dr. Ables has won numerous awards in both clinical practice and research. She has been nominated to the Alpha Omega Alpha honor society, named to the Outstanding Resident Award Program, named a Laughlin Fellow by the American College of Psychiatrists, and received a NARSAD Young Investigator Award from the Brain & Behavior Research Foundation, a Pathways Award from Alkermes, Inc. and a research grant from the Whitehall Foundation.
Dr. Ables works in the Student Trainee Mental Health Program at Icahn School of Medicine one day a week and conducts research on the basic biology underlying mental illness the other four days of the week. Dr. Ables practices general psychiatry and her reserch interests are in the effects of diabetes on the brain and the mechanisms underlying tolerance and addiction.
Language
English
Position
ASSISTANT PROFESSOR | Psychiatry, ASSISTANT PROFESSOR | Neuroscience
Hospital Affiliations
- Mount Sinai Queens
- The Mount Sinai Hospital
Research Topics
Addiction, Bioinformatics, Brain, Depression, Diabetes, Metabolism, Molecular Biology, Neuroscience, Post-Transcriptional Processing, RNA, Systems Neuroscience, Transcriptional Activation and Repression, Transgenic Mice
Multi-Disciplinary Training Areas
Neuroscience [NEU]
Download the CVClinical Focus
- Adjustment Disorder
- Anxiety
- Attention Deficit Hyperactivity Disorder And Attention Deficit Disorder
- Bipolar Disorder
- Depression
- Drug Abuse And Drug Addiction
- Generalized Anxiety Disorder
- Mental Health Services
- Mental Illness
- Mood Disorders
- Schizophrenia
- Seasonal Affective Disorder
- Social Anxiety Disorder
- Suicidal Tendencies
Education
PhD, University of Texas Southwestern Medical Center
MD, Icahn School of Medicine at Mount Sinai
MD, Mount Sinai School of Medicine
, The Rockefeller University
, Mount Sinai Hospital
Residency, Psychiatry
Mount Sinai Hospital
Awards
2019
NARSAD Young Investigator
Brain & Behavior Foundation
2019
Fellow
Alpha Omega Alpha Honor Society
2019
Laughlin Fellow
American College of Psychiatrists
2019
Class Participant
Career Development Institute in Psychiatry
2018
Fellow in Neuroscience
Leon Levy Foundation
2017
Outstanding Resident Award
National Institute of Mental Health
Research
The goal of our research is to better understand the effects of chronic metabolic diseases, such as diabetes, on brain function. Given the high utilization of energy by the brain, we aim to explore the implications of altered metabolism at the behavioral, circuit, cellular and molecular levels. Currently, we use animal models of diabetes to identify the ways in which long-term exposure to hyperglycemia can lead to increased susceptibility to stress and to addiction- or depression- or anxiety-like syndromes. A major focus of our work is on hyperglycemia-induced changes in gene expression and chromatin structure within the brain’s reward and aversion circuitry, and the mechanisms by which those lasting adaptations alter neuronal and circuit function to produce behavioral abnormalities. Our goal is to eventually translate these findings to human patients.
Insurance Information
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Publications
Selected Publications
- Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes. Chinonso A. Nwakama, Romain Durand-de Cuttoli, Zainab M. Oketokoun, Samantha O. Brown, Jillian E. Haller, Adriana Méndez, Mohammad Jodeiri Farshbaf, Y. Zoe Cho, Sanjana Ahmed, Sophia Leng, Jessica L. Ables, Brian M. Sweis. Communications Biology
- A Phase 1 single ascending dose study of pure oral harmine in healthy volunteers. Jessica L. Ables, Leah Israel, Olivia Wood, Usha Govindarajulu, Rachel T. Fremont, Ronjon Banerjee, Hongtao Liu, Jeremy Cohen, Peng Wang, Kunal Kumar, Geming Lu, Robert J. DeVita, Adolfo Garcia-Ocaña, James W. Murrough, Andrew F. Stewart. Journal of Psychopharmacology
- STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit. Mohammad Jodeiri Farshbaf, Taelor A. Matos, Kristi Niblo, Yacoub Alokam, Jessica L. Ables. Frontiers in Cellular Neuroscience
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Ables has not yet completed reporting of Industry relationships.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.