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Profile image of Jessica L Ables (JESSICA LYNN ABLES)
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Jessica L Ables, MD, PhD

JESSICA LYNN ABLES (Preferred Name)

Psychiatry

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Clinical Focus

Education

PhD, University of Texas Southwestern Medical Center

MD, Icahn School of Medicine at Mount Sinai

MD, Mount Sinai School of Medicine

, The Rockefeller University

, Mount Sinai Hospital

Residency, Psychiatry

Mount Sinai Hospital

Awards

2019

NARSAD Young Investigator

Brain & Behavior Foundation

2019

Fellow

Alpha Omega Alpha Honor Society

2019

Laughlin Fellow

American College of Psychiatrists

2019

Class Participant

Career Development Institute in Psychiatry

2018

Fellow in Neuroscience

Leon Levy Foundation

2017

Outstanding Resident Award

National Institute of Mental Health

Research

Recent research has revealed that neuronal axons have specialized mechanisms to regulate delivery and utilization of mRNAs independently of the neuronal cell body, where the nucleus resides. This is not surprising given that in many cases (e.g. motor neurons in the limbs), the axons are far removed from the cell body and require the ability to respond to stimuli on timescales that would prohibit gene expression from the nucleus and subsequent delivery to the distal axon. Projection neurons in the brain provide a unique opportunity to profile the transcripts that are utilized in discrete compartments of the cell, as the axons are physically separate from the cell body. Our lab is currently profiling axonal transcriptomes in specific cell populations in the normal mouse brain. Our goal is to determine how translation is locally regulated in response to various stimuli, including stress and metabolic derangements.

Insurance Information

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