Publications:27
- Mount Sinai Doctors
Jessica L Ables, MD, PhD
JESSICA LYNN ABLES (Preferred Name)
Psychiatry
No Patient Experience Ratings
About Me
Dr. Jessica Ables is an Assistant Professor of Psychiatry and Neuroscience at the Icahn School of Medicine at Mount Sinai, a New York State licensed physician and an ABPN board-certified psychiatrist. Dr. Ables completed her undergraduate education in Chemistry at Southwestern University in Georgetown, TX. She then entered the Medical Scientist Training Program at UT Southwestern Medical Center in Dallas, where she completed her PhD in Integrative Biology. She then transferred to Mount Sinai to complete her medical schooling, graduating. After medical school, Dr. Ables went to The Rockefeller University for a 4 year postdoctoral fellowship in molecular Neuroscience prior to returning to Mount Sinai to complete her residency training in Psychiatry.
Dr. Ables has won numerous awards in both clinical practice and research. She has been nominated to the Alpha Omega Alpha honor society, named to the Outstanding Resident Award Program, named a Laughlin Fellow by the American College of Psychiatrists, and received a NARSAD Young Investigator Award from the Brain & Behavior Research Foundation, a Pathways Award from Alkermes, Inc. and a research grant from the Whitehall Foundation.
Dr. Ables works in the Student Trainee Mental Health Program at Icahn School of Medicine one day a week and conducts research on the basic biology underlying mental illness the other four days of the week. Dr. Ables practices general psychiatry and her reserch interests are in the effects of diabetes on the brain and the mechanisms underlying tolerance and addiction.
Language
English
Position
ASSISTANT PROFESSOR | Psychiatry, ASSISTANT PROFESSOR | Neuroscience
Hospital Affiliations
- Mount Sinai Queens
- The Mount Sinai Hospital
Research Topics
Addiction, Bioinformatics, Brain, Depression, Diabetes, Metabolism, Molecular Biology, Neuroscience, Post-Transcriptional Processing, RNA, Systems Neuroscience, Transcriptional Activation and Repression, Transgenic Mice
Multi-Disciplinary Training Areas
Neuroscience [NEU]
Download the CVClinical Focus
- Adjustment Disorder
- Anxiety
- Attention Deficit Hyperactivity Disorder And Attention Deficit Disorder
- Bipolar Disorder
- Depression
- Drug Abuse And Drug Addiction
- Generalized Anxiety Disorder
- Mental Health Services
- Mental Illness
- Mood Disorders
- Schizophrenia
- Seasonal Affective Disorder
- Social Anxiety Disorder
- Suicidal Tendencies
Education
PhD, University of Texas Southwestern Medical Center
MD, Icahn School of Medicine at Mount Sinai
MD, Mount Sinai School of Medicine
, The Rockefeller University
, Mount Sinai Hospital
Residency, Psychiatry
Mount Sinai Hospital
Awards
2019
NARSAD Young Investigator
Brain & Behavior Foundation
2019
Fellow
Alpha Omega Alpha Honor Society
2019
Laughlin Fellow
American College of Psychiatrists
2019
Class Participant
Career Development Institute in Psychiatry
2018
Fellow in Neuroscience
Leon Levy Foundation
2017
Outstanding Resident Award
National Institute of Mental Health
Research
The interpeduncular nucleus (IPN) is a GABAergic nucleus that is characterized by high expression of neuronal nitric oxide synthase (Nos1) as well as striking vascularity. We have recently found that Nos1 is increased in IPN after chronic exposure to nicotine. We hypothesize that this increase in Nos1 mediates the development of tolerance to the aversive effects of nicotine, as we found that eliminating Nos1 in the IPN reduces preference for a rewarding dose of nicotine (Ables et al. PNAS 2017). Our goal is to determine if this increase in Nos1 in the IPN generalizes to other drugs of abuse or to stress and might represent a target for treatment of addiction. Future studies will focus on visualizing nitric oxide release from the IPN and the effects of nitric oxide on the epigenome, transcriptome and function of neurons in the reward circuitry.
Insurance Information
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.
Publications
Selected Publications
- Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes. Chinonso A. Nwakama, Romain Durand-de Cuttoli, Zainab M. Oketokoun, Samantha O. Brown, Jillian E. Haller, Adriana Méndez, Mohammad Jodeiri Farshbaf, Y. Zoe Cho, Sanjana Ahmed, Sophia Leng, Jessica L. Ables, Brian M. Sweis. Communications Biology
- A Phase 1 single ascending dose study of pure oral harmine in healthy volunteers. Jessica L. Ables, Leah Israel, Olivia Wood, Usha Govindarajulu, Rachel T. Fremont, Ronjon Banerjee, Hongtao Liu, Jeremy Cohen, Peng Wang, Kunal Kumar, Geming Lu, Robert J. DeVita, Adolfo Garcia-Ocaña, James W. Murrough, Andrew F. Stewart. Journal of Psychopharmacology
- STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit. Mohammad Jodeiri Farshbaf, Taelor A. Matos, Kristi Niblo, Yacoub Alokam, Jessica L. Ables. Frontiers in Cellular Neuroscience
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Ables has not yet completed reporting of Industry relationships.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.