
Jordi Ochando, PhD
About Me
Jordi Ochando, Ph.D. is an Assistant Professor of Oncological Sciences and Director of the Flow Cytometry CoRE at the Icahn School of Medicine at Mount Sinai. The Ochando laboratory investigates the origin, development, and immune function of macrophages in organ transplantation. His laboratory has recently discovered that trained immunity represents a previously unrecognized pathway that mediates allograft rejection. To prevent the detrimental effects of trained macrophages, the Ochando laboratory uses a novel revolutionary targeted therapeutic delivery approach in which drug-loaded nanobiologics that specifically target macrophages in vivo and induce long-term allograft acceptance. This research represents a compelling framework for developing novel targeted therapies that promote immunological tolerance.
Language
English
Position
ASSISTANT PROFESSOR | Oncological Sciences, ASSISTANT PROFESSOR | Medicine, Nephrology, ASSISTANT PROFESSOR | Immunology & Immunotherapy
Research Topics
Cancer, Dendritic Cells, Growth, Immunological Tolerance, Transplantation
Multi-Disciplinary Training Areas
Immunology [IMM]
Education
BSc, University of Alicante
PhD, De Montfort University
Publications
Selected Publications
- In vitro protocol demonstrating five functional steps of trained immunity in mice: Implications on biomarker discovery and translational research. Maria González-Pérez, Jana Baranda, Leticia Pérez-Rodríguez, Patricia Conde, Carlos de la Calle-Fabregat, Marcos J. Berges-Buxeda, Alexander Dimitrov, Javier Arranz, Sergio Rius-Rocabert, Alessia Zotta, Ana Dopazo, Nikita Poddar, Xuedi Wang, Estanislao Nistal-Villán, Raphaël Duivenvoorden, Joren C. Madsen, David L. Williams, Dan Hasson, Daniel Lozano-Ojalvo, Florent Ginhoux, Luke A.J. O’Neill, Jordi Ochando. Cell Reports
- Potential Impact of Extracorporeal Photopheresis on Trained Immunity and Organ Transplant Acceptance. Clémentine Tocco, Jordi Ochando. Transplantation Direct
- Author Correction: LILRB3 genetic variation is associated with kidney transplant failure in African American recipients (Nature Medicine, (2025), 31, 5, (1677-1687), 10.1038/s41591-025-03568-z). Zeguo Sun, Zhengzi Yi, Chengguo Wei, Wenlin Wang, Tianyuan Ren, Paolo Cravedi, Fasika Tedla, Stephen C. Ward, Evren Azeloglu, Daniel R. Schrider, Yun Li, Atlas Khan, Francesca Zanoni, Jia Fu, Sumaria Ali, Shun Liu, Deguang Liang, Tong Liu, Hong Li, Caixia Xi, Thi Ha Vy, Gohar Mosoyan, Quan Sun, Ashwani Kumar, Zhongyang Zhang, Samira Farouk, Kirk Campell, Jordi Ochando, Kyung Lee, Steve Coca, Jenny Xiang, Patricia Connolly, Lorenzo Gallon, Philip J. O’Connell, Robert Colvin, Madhav C. Menon, Girish Nadkarni, John C. He, Monica Kraft, Xuejun Jiang, Xuewu Zhang, Krzysztof Kiryluk, Aravind Cherukuri, Fadi G. Lakkis, Weiguo Zhang, Shu Hsia Chen, Peter S. Heeger, Weijia Zhang. Nature Medicine