Kateri Moore | Mount Sinai

About Me

My laboratory is studying both the basic biology and molecular mechanisms that make a hematopoietic stem cell a self-renewing stem cell that sustains our blood system throughout life. We do this by investigating these properties in model systems and by trying to convert other cell types into hematopoietic stem cells for eventual therapeutic uses. https://neuroscience.mssm.edu/DLabs/labs/lm.html

Language

English

Position

PROFESSOR EMERITUS | Cell, Developmental & Regenerative Biology

Research Topics

Aging, Bioinformatics, Cell Adhesion, Cell Biology, Cell Cycle, Cell Division, Cellular Differentiation, Developmental Biology, Epigenetics, Gene Discovery, Genomics, Hematopoiesis, Mathematical Modeling of Biomedical Systems, Molecular Biology, Stem Cells, Transcription Factors, Transgenic Mice

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Education

BS, Kansas State University

DVM, Kansas State University

Post Doctoral, Baylor College of Medicine

Awards

2014

R01 HL119404-01A1

NIH/NHLBI

1988

National Research Service Award

National Institutes of Health

Research

Specific Clinical/Research Interest: Stem Cells/Microenvironment/Stem Cell Niche, Molecular regulation of hematopoietic stem cell self renewal and differentiation, molecular interaction of stem cells and microenvironmental elements. Direct differentiation of somatic cells into hematopoietic stem cells.

Current Students: Jeffrey Bernitz
Michael Daniel
Andreia Gomes
Research Personnel: Ying Liu
Summary of Research Studies: Primary research interest is in defining the cellular and molecular nature of the hematopoietic stem cells (HSCs) and in particular the molecular cross-talk between stem cells and their niche. Approach is to use mouse models to study HSC during normal homeostasis and after stress. Also using specific factors to directly induce HSCs from somatic cells to develop patient specific stem cells and differentiated blood products for cell replacement therapies.