
Lahouaria Hadri, PhD
About Me
Dr. Hadri graduated from the University PARIS XI, Faculty of Pharmacy, Châtenay-Malabry in 2005. In 2006, she relocated to the United States and undertook a postdoc position at Massachusetts General Hospital, Harvard Medical School in Boston, and in 2007 she moved with the team to Icahn School of Medicine at Mount Sinai, in New York City. The Hadri Lab focuses on cardiovascular diseases, pulmonary arterial hypertension (PAH), and idiopathic pulmonary fibrosis (IPF). The current research objective is to provide an in-depth analysis of calcium handling proteins’ roles and their cellular signaling networks in cardiovascular and lung diseases and define a platform for the design of innovative therapeutic strategies using gene and drug targeted therapies. The lab has also a particular interest in exploring the role of epigenetic modifications and SIN3a/histone deacetylase complex in various cardiopulmonary diseases.
Language
English
Position
ASSOCIATE PROFESSOR | Pharmacological Sciences, ASSOCIATE PROFESSOR | Medicine, Cardiology
Research Topics
Biomedical Sciences, Cardiovascular, Cell Biology, Cell Cycle, Chromatin, Fibrosis, Gene Expressions, Gene Regulation, Gene Therapy, Transcription Factors, Transgenic Mice, Translational Research
Multi-Disciplinary Training Areas
Disease Mechanisms and Therapeutics (DMT)
Publications
Selected Publications
- Extracellular-cAMP suppresses pulmonary arterial hypertension-induced ventricular arrhythmias. Marine Cacheux, Benjamin Strauss, Shestruma Parajuli, Aymen Halouani, Michael G. Katz, Seun Imani, Samar Antar, Nestor Bedoya, Lahouaria Hadri, Fadi G. Akar, Yassine Sassi. Journal of Molecular and Cellular Cardiology
- Long-lasting sex-specific alteration in left ventricular cardiac transcriptome following gamma and simGCRsim radiation. Roksana Zakharyan, Siras Hakobyan, Agnieszka Brojakowska, Suren Davitavyan, Ani Stepanyan, Tamara Sirunyan, Gisane Khachatryan, Mary K. Khlgatian, Malik Bisserier, Shihong Zhang, Susmita Sahoo, Lahouaria Hadri, Venkata Naga Srikanth Garikipati, Arsen Arakelyan, David A. Goukassian. Scientific Reports
- Pharmacological inhibition of Epac1 protects against pulmonary fibrosis by blocking FoxO3a neddylation. Katherine Jankowski, Sarah E. Lemay, Daniel Lozano-Ojalvo, Leticia Pérez-Rodríguez, Mélanie Sauvaget, Sandra Breuils-Bonnet, Karina Formoso, Vineeta Jagana, Maria T. Ochoa, Shihong Zhang, Javier Milara, Julio Cortijo, Irene C. Turnbull, Steeve Provencher, Sebastien Bonnet, Jordi Ochando, Frank Lezoualc’h, Malik Bisserier, Lahouaria Hadri. European Respiratory Journal