Publications:133
Lap Ho, PhD
About Me
Dr. Ho is trained in nutrition, biochemistry, and molecular biology, with more than 20 years of experience in translational neuroscience research in Alzheimer’s disease (AD). Dr. Ho's work has generated insights on the molecular mechanisms underlying the onset and progression of AD, and this information has been translated into multiple therapeutic developments. To date, Dr. Ho's research has resulted in over 111 papers published in peer-reviewed journals. Dr. Ho have extensive experience with experimental and preclinical studies characterizing the bioactivities of polyphenol components in the brain and the beneficial impacts of dietary supplementation with polyphenol preparations in reducing AD mechanisms in mouse models. A listing of Dr. Ho's publications is available online: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/48469360/?sort=date&direction=descending
Language
English
Position
ASSOCIATE PROFESSOR | Genetics and Genomic Sciences
Publications
Selected Publications
- Structural insights enable drug discovery for the neuronal NBCn2 carbonate transporter. Shifan Yang, Yihan Zhao, Sezen Vatansever, Gregory Zilberg, Michael J. Capper, Jinglong Zhang, Joshua Stamos, Keino Hutchinson, Audrey L. Warren, Alexander C. Stone, Anwar Abbassi, Eric Purisic, Lap Ho, Aiqun Li, Jinye Dai, Avner Schlessinger, Bin Zhang, Daniel Wacker. Nature Communications
- Molecular Networks and Key Regulators Underlying Resilience of the Human Brain to Aging and Dementia. Lei Guo, Nicholas Grimaldi, Minghui Wang, Lap Ho, Ben Shackleton, Ryan Neff, Erming Wang, Zhidong Tu, Sam Gandy, Vahram Haroutunian, Michelle E. Ehrlich, Charles Mobbs, Bin Zhang. Biomolecules
- Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease. Yong Huang, Minghui Wang, Haofei Ni, Jinglong Zhang, Aiqun Li, Bin Hu, Chrystian Junqueira Alves, Shalaka Wahane, Mitzy Rios de Anda, Lap Ho, Yuhuan Li, Sangjo Kang, Ryan Neff, Ana Kostic, Joseph D. Buxbaum, John F. Crary, Kristen J. Brennand, Bin Zhang, Hongyan Zou, Roland H. Friedel. Nature Neuroscience
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Ho has not yet completed reporting of industry relationships or has no industry relationships to report.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.