
Lap Ho, PhD
About Me
Dr. Ho is trained in nutrition, biochemistry, and molecular biology, with more than 20 years of experience in translational neuroscience research in Alzheimer’s disease (AD). Dr. Ho's work has generated insights on the molecular mechanisms underlying the onset and progression of AD, and this information has been translated into multiple therapeutic developments. To date, Dr. Ho's research has resulted in over 111 papers published in peer-reviewed journals. Dr. Ho have extensive experience with experimental and preclinical studies characterizing the bioactivities of polyphenol components in the brain and the beneficial impacts of dietary supplementation with polyphenol preparations in reducing AD mechanisms in mouse models. A listing of Dr. Ho's publications is available online: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/48469360/?sort=date&direction=descending
Language
English
Position
ASSOCIATE PROFESSOR | Genetics and Genomic Sciences
Publications
Selected Publications
- Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease. Yong Huang, Minghui Wang, Haofei Ni, Jinglong Zhang, Aiqun Li, Bin Hu, Chrystian Junqueira Alves, Shalaka Wahane, Mitzy Rios de Anda, Lap Ho, Yuhuan Li, Sangjo Kang, Ryan Neff, Ana Kostic, Joseph D. Buxbaum, John F. Crary, Kristen J. Brennand, Bin Zhang, Hongyan Zou, Roland H. Friedel. Nature Neuroscience
- Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson’s disease. Qian Wang, Minghui Wang, Insup Choi, Lily Sarrafha, Marianna Liang, Lap Ho, Kurt Farrell, Kristin G. Beaumont, Robert Sebra, Claudia De Sanctis, John F. Crary, Tim Ahfeldt, Joel Blanchard, Drew Neavin, Joseph Powell, David A. Davis, Xiaoyan Sun, Bin Zhang, Zhenyu Yue. Science advances
- Benefits of dietary polyphenols in Alzheimer’s disease. Farida El Gaamouch, Fiona Chen, Lap Ho, Hsiao Yun Lin, Chongzhen Yuan, Jean Wong, Jun Wang. Frontiers in Aging Neuroscience