Larry Di Fabrizio
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Larry Di Fabrizio, MD

Internal Medicine, Pulmonary Medicine (Lung), Critical Care, Sleep Medicine

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About Me

Dr. Larry Di Fabrizio has joined Mount Sinai on July 2, 2012 as the Director of the Pulmonary Faculty Practice and Associate Professor in the Department of Medicine in the Division of Pulmonary, Critical Care & Sleep Medicine.  He is a seasoned clinician with a strong academic background with more than two decades of private practice in NYC while also serving as a fellowship training Program Director for over a decade, most recently at Lenox Hill Hospital and previously at St. Vincent’s Hospital.

Dr. Di Fabrizio’s goal at Mount Sinai is to translate cutting edge scientific breakthroughs into clinical practice.

Dr. Di Fabrizio, a graduate of Columbia College, received his medical degree with distinction from Washington University in St. Louis. He interned and served as a medical resident and fellow in Pulmonary and Critical Care Medicine at the Brigham and Women’s Hospital, at Harvard Medical School.

During his medical school years, he worked as a visiting student at Mount Sinai Hospital in the laboratory of Dr. James Holland, the Director of Neoplastic Diseases, and later spent a year conducting research at the Dana-Farber Cancer Center. After his clinical training, he joined the laboratory of Dr. Leonard Chess at Columbia University under a Research Fellowship in Cellular Immunology. Dr. Di Fabrizio received the American Lung Association and Howard Hughes Fellowship Training Grants and subsequently joined the full-time faculty at Columbia Medical School in the Division of Pulmonary and Critical Care Medicine. 

In 1991 Dr. Di Fabrizio was recruited to become the Associate Chief of Pulmonary Medicine, Program Director of the Pulmonary Fellowship and Director of the Pulmonary Function and Sleep Laboratories at St. Vincent’s Medical Center in New York City.  Working in collaboration with the Department of Nuclear Medicine, he studied diagnostic strategies for pulmonary HIV disorders. He also served on St. Vincent’s TB Task Force during the height of the multi-drug-resistant TB epidemic.

In 1996 Dr. Di Fabrizio joined Lenox Hill Hospital as the Associate Chief of Pulmonary Medicine and Associate Training Program Director and was appointed the Program Director of the Pulmonary Fellowship in 2006. Under his leadership, the Pulmonary Training Fellowship Program received commendations from the ACGME for the comprehensive curriculum manual developed by Dr. Di Fabrizio, and in 2011 the program was expanded and converted to a combined Pulmonary-Critical Care Fellowship Program.   At Lenox Hill, he served on the Critical Care Task Force which modernized the Intensive Care Units.  He also served on the Hospital Investigational Review Board and Department of Medicine Quality Improvement Committees. As a recognized leader he developed a large private clinical practice and was elected by the medical staff to the hospital’s Medical Board representing the Physician Attending Association.

PROFESSOR | Medicine, Pulmonary, Critical Care and Sleep Medicine
Hospital Affiliations
  • Mount Sinai Queens
  • The Mount Sinai Hospital