
Lauren A Peters, PhD
About Me
Lauren Peters, M.A., Ph.D, is an Assistant Professor in the Department of Genetics and Genomic Sciences and a faculty member of the Icahn Genomics Institute. Dr. Peters was trained in immunology, genetics and computational biology. Her research focuses on the discovery of how rare and common genetic drivers of known immune mediated and as yet, unknown, immune drivers of other systemic and organ specific diseases, function in pathology. Her research is applied to the design of next generation in silico models of disease by the integration of clinical electronic medical record with multi-omics profiling of the disease tissue from specific patient populations. Through this approach, she defines patient data driven mechanisms of disease pathogenesis and identification of novel patient subsets, biomarkers and approaches to therapeutic discovery with disease target phenotyping and experimental validation. Dr. Peters also led the Disease Discovery group at Sema4, a patient centric health company since 2017. Prior to joining Mount Sinai, Dr. Peters was a scientist in oncology therapeutic discovery in the Cell Biology group at Imclone Systems, Eli Lilly and worked in business development at Regeneron. Dr. Peters has worked in Information Technology at Barclays and management consulting at Kaiser Associates where she advised Fortune 100 clients in the pharmaceutical, technology, consumer products, and aerospace and defense industries on business strategy.
Language
English
Position
ADJUNCT ASSISTANT PROFESSOR | Genetics and Genomic Sciences
Research Topics
Autoimmunity, Bioinformatics, Computational Biology, Drug Design and Discovery, Genomics, Immune Deficiency, Inflammation, Inflammatory Bowel Disease (IBD), Mucosal Immunology
Education
BA, Boston University
MA, Columbia University
PhD, Icahn School of Medicine at Mount Sinai
Publications
Selected Publications
- Inflammation rewires the enteric nervous system through neurogenic monocyte recruitment. Sravya Kurapati, Changsik Shin, Krisztina Szabo, Yu Liu, Azree Z. Ashraf, Balazs Koscso, Chinmayee Dash, Katherine L. Kruckow, Leonardo E. Navarro, Amanda M. Clark, Monalee Saha, Sushma Nagaraj, Wenhui Wang, Jun Zhu, Kevin Brown, Travis Thomson, Natalia Shulzhenko, Andrey Morgun, Christina E. Baer, Shanthi Srinivasan, Subhash Kulkarni, Pankaj J. Pasricha, Lauren A. Peters, Milena Bogunovic. Journal of Experimental Medicine
- A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients. Lauren A. Peters, Joshua R. Friedman, Aleksandar Stojmirovic, Jacob Hagen, Sander Houten, Tetyana Dodatko, Mariana P. Amaro, Paula Restrepo, Zhi Chai, J. Rodrigo Mora, Holly A. Raymond, Mark Curran, Radu Dobrin, Anuk Das, Huabao Xiong, Eric E. Schadt, Carmen Argmann, Bojan Losic. Communications Biology
- Biopsy and blood-based molecular biomarker of inflammation in IBD. Carmen Argmann, Ruixue Hou, Ryan C. Ungaro, Haritz Irizar, Zainab Al-Taie, Ruiqi Huang, Roman Kosoy, Swati Venkat, Won Min Song, Antonio F. Di'narzo, Bojan Losic, Ke Hao, Lauren Peters, Phillip H. Comella, Gabrielle Wei, Ashish Atreja, Milind Mahajan, Alina Iuga, Prerak T. Desai, Patrick Branigan, Aleksandar Stojmirovic, Jacqueline Perrigoue, Carrie Brodmerkel, Mark Curran, Joshua R. Friedman, Amy Hart, Esi Lamousé-Smith, Jan Wehkamp, Saurabh Mehandru, Eric E. Schadt, Bruce E. Sands, Marla C. Dubinsky, Jean Frederic Colombel, Andrew Kasarskis, Mayte Suárez-Fariñas. Gut