Leigh Goedeke, PhD

Dr. Leigh Goedeke received her BS in Biology from Gettysburg College in 2009 and PhD in Biomedical Sciences from NYU School of Medicine in 2015. After completing her postdoctoral training at Yale School of Medicine, Dr. Goedeke was recruited to the Cardiovascular Research Institute at the Icahn School of Medicine at Mount Sinai in the Spring of 2022, where she is currently an Assistant Professor of Medicine (Cardiology and Endocrinology). Dr. Goedeke’s research focuses on understanding how altered mitochondrial function–and more broadly metabolism– contributes to type 2 diabetes and residual cardiovascular disease risk. Using a combination of in vivo physiology, molecular biology, stable isotope tracer methodology and integrative multi-omics, her laboratory explores the critical metabolic pathways that underlie atherosclerotic plaque progression and vulnerability. Specifically, the lab is focused on two integrated areas of research: i) identification of novel metabolic hubs that regulate traditional atherosclerotic risk factors and ii) mitochondrial energy metabolism and vessel wall heterogeneity in diabetic atherosclerosis.