Publications:59
Lior Zangi, PhD
About Me
Dr. Lior Zangi is an Associate Professor of Medicine, Cardiology, and Genetics and Genomic Sciences and a faculty member of the Icahn Genomics Institute.
Language
English
Position
ASSOCIATE PROFESSOR | Medicine, Cardiology, ASSOCIATE PROFESSOR | Genetics and Genomic Sciences
Research Topics
Regeneration, Stem Cells
Multi-Disciplinary Training Areas
Development Regeneration and Stem Cells [DRS]
Education
BSc,, Hebrew University
MSc, Hebrew University Hadassah-Medical School
PhD, Weizmann Institute of Science
Awards
2014
American Heart Association (AHA) Summer 2013 Postdoctoral Fellowship Award.
American Heart Association (AHA)
Research
My lab research focuses on cardiac regeneration and on the role of
adult cardiac stem cells in the healthy and injured heart.
Our main goal is to unravel paracrine signals that can enhance cardiac
regeneration after injury. Therefore, we are using modified mRNA as a novel
gene delivery tool to locally up-regulate or down-regulate paracrine factors
after myocardial infarction in small and large animal models.
adult cardiac stem cells in the healthy and injured heart.
Our main goal is to unravel paracrine signals that can enhance cardiac
regeneration after injury. Therefore, we are using modified mRNA as a novel
gene delivery tool to locally up-regulate or down-regulate paracrine factors
after myocardial infarction in small and large animal models.
Publications
Selected Publications
- A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy-Induced Cardiotoxicity. Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi. Advanced Science
- A tumor-selective mRNA system enables precision cancer treatment. Magdalena M. Żak, Jimeen Yoo, Alberto Utrero-Rico, Wencke Walter, Gayatri Mainkar, Matthew Adjmi, Ann Anu Kurian, Ashikur Rahaman, Daniel Lozano Ojalvo, Jordi Ochando, Torsten Haferlach, Ramon E. Parsons, Filip K. Swirski, Lior Zangi. Molecular Therapy
- Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart. Jeffrey Downey, Ana Oliveira-Coelho, Máté G. Kiss, Gabriel Laghlali, Alexander Leunig, Emir Radkevich, Laszlo Halasz, Martin Umali, Joana Ferreira da Silva, Madeline L. Eller, Matteo Gianeselli, Magdalena M. Żak, Haley E. Randolph, Gabriel Caumartin, Wolfram C. Poller, Henrike Janssen, Laura L. Koekkoek, Jamshid Abdul-Ghafar, Pacific Huynh, Darwin D'Souza, Vladimir Roudko, Sheqouia Nauta, Jazz Munitz, Xisheng Li, Thomas Rathner, Ziche Chen, Anh Phan, Abigail Glick, Katarzyna Cialowicz, Zhihong Chen, Seunghee Kim-Schulze, Seonghun Yoon, Matthias Nahrendorf, Susmita Sahoo, Miriam Merad, Adolfo García-Sastre, Cameron S. McAlpine, Gustav J. Strijkers, Viviana Simon, Rachel Brody, Saurabh Mehandru, Zahi A. Fayad, Benjamin P. Kleinstiver, Lior Zangi, Mandy M.T. van Leent, Michael Schotsaert, Filip K. Swirski. Immunity