Publications:61
Lior Zangi, PhD
About Me
Dr. Lior Zangi is an Associate Professor of Medicine, Cardiology, and Genetics and Genomic Sciences and a faculty member of the Icahn Genomics Institute.
Language
English
Position
PROFESSOR | Medicine, Cardiology, PROFESSOR | Genetics and Genomic Sciences
Research Topics
Regeneration, Stem Cells
Multi-Disciplinary Training Areas
Development Regeneration and Stem Cells [DRS]
Education
B.Sc.,, Hebrew University
M.Sc., Hebrew University Hadassah-Medical School
Ph.D., Weizmann Institute of Science
Awards
2014
American Heart Association (AHA) Summer 2013 Postdoctoral Fellowship Award.
American Heart Association (AHA)
Research
My lab research focuses on cardiac regeneration and on the role of
adult cardiac stem cells in the healthy and injured heart.
Our main goal is to unravel paracrine signals that can enhance cardiac
regeneration after injury. Therefore, we are using modified mRNA as a novel
gene delivery tool to locally up-regulate or down-regulate paracrine factors
after myocardial infarction in small and large animal models.
adult cardiac stem cells in the healthy and injured heart.
Our main goal is to unravel paracrine signals that can enhance cardiac
regeneration after injury. Therefore, we are using modified mRNA as a novel
gene delivery tool to locally up-regulate or down-regulate paracrine factors
after myocardial infarction in small and large animal models.
Publications
Selected Publications
- Optimization of Therapeutic modRNA Delivery to the Lung for Prevention of Pulmonary Fibrosis. Gayatri Mainkar, Magdalena M. Zak, Matteo Ghiringhelli, Jimeen Yoo, Matthew Adjmi, Keerat Kaur, Lior Zangi. Pharmaceutics
- Reprogramming the diseased liver: antioxidant-engineered mRNA nanoparticles as microenvironment modulators in MAFLD. Matteo Ghiringhelli, Lior Zangi. Immunometabolism (United States)
- Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart. Jeffrey Downey, Ana Oliveira-Coelho, M. G. Kiss, Gabriel Laghlali, Alexander Leunig, Emir Radkevich, Laszlo Halasz, Martin Umali, Joana Ferreira da Silva, Madeline L. Eller, Matteo Gianeselli, Magdalena M. Żak, Haley E. Randolph, Gabriel Caumartin, Wolfram C. Poller, Henrike Janssen, Laura L. Koekkoek, Jamshid Abdul-Ghafar, Pacific Huynh, Darwin D’Souza, Vladimir Roudko, Sheqouia Nauta, Jazz Munitz, Xisheng Li, Thomas Rathner, Ziche Chen, Anh Phan, Abigail Glick, Katarzyna Cialowicz, Zhihong Chen, Seunghee Kim-Schulze, Seonghun Yoon, Matthias Nahrendorf, Susmita Sahoo, Miriam Merad, Adolfo García-Sastre, Cameron S. McAlpine, Gustav J. Strijkers, Viviana Simon, Rachel Brody, Saurabh Mehandru, Zahi A. Fayad, Benjamin P. Kleinstiver, Lior Zangi, Mandy M.T. van Leent, Michael Schotsaert, Filip K. Swirski. Immunity
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Zangi has not yet completed reporting of industry relationships or has no industry relationships to report.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.