Publications:57
Lior Zangi, PhD
About Me
Dr. Lior Zangi is an Associate Professor of Medicine, Cardiology, and Genetics and Genomic Sciences and a faculty member of the Icahn Genomics Institute.
Language
English
Position
ASSOCIATE PROFESSOR | Medicine, Cardiology, ASSOCIATE PROFESSOR | Genetics and Genomic Sciences
Research Topics
Regeneration, Stem Cells
Multi-Disciplinary Training Areas
Development Regeneration and Stem Cells [DRS]
Education
BSc,, Hebrew University
MSc, Hebrew University Hadassah-Medical School
PhD, Weizmann Institute of Science
Awards
2014
American Heart Association (AHA) Summer 2013 Postdoctoral Fellowship Award.
American Heart Association (AHA)
Research
My lab research focuses on cardiac regeneration and on the role of
adult cardiac stem cells in the healthy and injured heart.
Our main goal is to unravel paracrine signals that can enhance cardiac
regeneration after injury. Therefore, we are using modified mRNA as a novel
gene delivery tool to locally up-regulate or down-regulate paracrine factors
after myocardial infarction in small and large animal models.
adult cardiac stem cells in the healthy and injured heart.
Our main goal is to unravel paracrine signals that can enhance cardiac
regeneration after injury. Therefore, we are using modified mRNA as a novel
gene delivery tool to locally up-regulate or down-regulate paracrine factors
after myocardial infarction in small and large animal models.
Publications
Selected Publications
- Transient overexpression of hPKM2 in porcine cardiomyocytes prevents heart failure after myocardial infarction. Jiacheng Sun, Yalin Wu, Matthew Adjmi, Rachel C. Matthews, Ann Anu Kurian, Magdalena M. Żak, Jimeen Yoo, Gayatri Mainkar, Hannah Lawless, Yu An Lu, Patrick Soon-Shiong, Gregory P. Walcott, Hesham A. Sadek, Jianyi Zhang, Lior Zangi. Nature Communications
- Pyruvate Kinase M2 Role in Cardiovascular Repair. Mohd Rihan, Lior Zangi, Ajit Magadum. Cells
- Clinical development of therapeutic mRNA applications. Magdalena M. Żak, Lior Zangi. Molecular Therapy