
Mayte Suarez-Farinas, PhD
About Me
I have vast experience in clinical trials design and statistical techniques as well as data mining and bioinformatics techniques applied to high throughput data, including arrays, next generation sequencing data, metabolomics and proteomics. For the last 10 years, I have been working in the interface of biomedical research, translational science and quantitative analysis, successfully developing collaborations with researchers of different areas of biomedical research at several institutions. I am a Research Assistant Professor at the Laboratory of Investigative Dermatology and the co-director of the biostatistics team at the Rockefeller University Clinical and Translational Science Center (CTSA), where I oversee the design of clinical and research protocols and participate in data analysis. I am skilled in multivariate and longitudinal analysis, time series, and pattern recognition and machine learning methods. My long terms goals are to develop robust statistical techniques to mine and integrate complex high throughput data, tailored to the specific disease model, especially on inflammatory skin diseases such as atopic dermatitis.
Language
English
Position
PROFESSOR | Population Health Science and Policy, PROFESSOR | Genetics and Genomic Sciences
Research Topics
Bioinformatics, Biostatistics, Gene Expressions, Genetics, Genomics, Inflammation, Systems Biology
Multi-Disciplinary Training Areas
Genetics and Genomic Sciences [GGS]
Education
MSc, University of Havana. School of Mathematics and Computer Sciences.
MSc, Catholic University of Rio de Janeiro. Computational Statistics Group
PhD, Catholic University of Rio de Janeiro. Computational Statistics Group
Postdoctoral Studies, The Rockefeller University. Laboratory of Mathematical Physics
Awards
2015
The Irma T. Hirschl / Monique Weill-Caulier Research Award
2005
Frederick Seitz Fellowship
Rockefeller University
2003
Woman in Science Postdoctoral Fellowship
Rockefeller University
1999
National Ph.D Fellowship
Brazilian National Research Council (CNPQ)
1997
National MsC. Fellowship
Brazilian Ministry of Education (CAPES)
1995
Abel Award (Best MSc Thesis)
University of Havana, School of Mathematics and Computer Scs.
1995
Diploma de Oro (graduated with Magna Cum Laude Honor)
University of Havana
Research
Dr. Suarez-Farinas works in the interface of biomedical research, translational science and quantitative analysis, developing robust statistical techniques to mine and integrate complex high-throughput data, tailored to the specific disease model, especially on inflammatory skin diseases. She have extensive experience in clinical trials design and statistical and bioinformatics techniques applied to high throughput data, including microarrays, next generation sequencing data, metabolomics and proteomics.
Dr. Suarez-Farinas’ research focus on using system biology approaches that combine mechanistic clinical trials and genomic data to unravel the pathogenesis of diseases, develop disease biomarkers and define targets for therapeutics.
Using bioinformatics analysis of high-throughput data, she had developed molecular phenotypes in psoriasis and atopic dermatitis that allows to reliably measure treatment response at the molecular level. This phenotypes facilitates faster screening for effective drugs, unambiguously benchmark multiple drugs in terms of the improvements they show at molecular level.
She develops predictive tools that uses genomic data to predict long-term treatment response to psoriasis treatment after a short course of treatment.
Publications
Selected Publications
- A Functional Genetic Score in the ZMIZ1/TGF-β/STAT Pathway Predicts Early Biologic Discontinuation in Psoriasis Patients Treated with Anti-TNF and Anti-IL12/23 Agents. Juan de Luque, Carmen Mochón-Jiménez, Irene Rivera-Ruiz, Jesús Gay-Mimbrera, Judilyn Fuentes-Duculan, Israel Coats, Macarena Aguilar-Luque, Beatriz Isla-Tejera, Antonio Vélez García Nieto, Manuel Galán-Gutiérrez, Teresa López Viñau López, Mayte Suarez-Fariñas, James G. Krueger, Juan Ruano. Advances in Therapy
- Kinetics of early peanut allergy development and resolution in the EAT, LEAP, and PAS cohorts. Ru Xin Foong, Henry T. Bahnson, George Du Toit, Michelle Huffaker, Hugh A. Sampson, Mayte Suárez-Fariñas, Kirsty Logan, Michael Perkin, Ronald van Ree, Alexandra F. Santos, Gideon Lack. Journal of Allergy and Clinical Immunology
- Kinetics of epitope-specific IgE and IgG<sub>4</sub> in early peanut allergy development and resolution. Mayte Suárez-Fariñas, Kyung Won Lee, Maria Suprun, Henry T. Bahnson, Ru Xin Foong, George Du Toit, Gideon Lack, Hugh A. Sampson. Journal of Allergy and Clinical Immunology