
Megan K Horton, PhD, MPH
About Me
Megan Horton, PhD, MPH, is Professor in the Department of Environmental Medicine at the Icahn School of Medicine at Mount Sinai. Her research at Mount Sinai combines state-of-the-art environmental exposure assessment with structural and functional neuroimaging and behavioral phenotyping to understand how early life exposure to developmental neurotoxicants impacts typical brain development and leads to aberrant cognitive and behavioral outcomes in children. Recently, her research extends to investigate how environmental, social and occupational stressors impact later life health outcomes including PTSD and cognitive impairment.
Dr. Horton’s research has been funded from grants from the National Institutes of Health (NIH), the National Institute of Occupational Safety and Health (NIOSH), the New York/New Jersey Educational Research Center (NY/NJERC) and the Honest Company. Her research is highly collaborative and involves several on going studies that are based in New York City, Italy, Mexico.
Dr. Horton earned her doctoral degree in Environmental Health Sciences at Mailman School of Public Health, Columbia University. During her doctoral training, she gained expertise in the development and use of biological markers to measure prenatal and early life exposures to environmental toxicants, focusing mainly on residential exposure to pesticides. Subsequently, she completed a postdoctoral fellowship at the Sergievsky Center for the Epidemiologic Study of Neurologic Diseases. The focus of this postdoc was to explore the use of brain imaging (i.e., magnetic resonance imaging – MRI) to investigate the impact of prenatal exposure to pesticides and secondhand smoke on neuropsychological and behavioral function throughout childhood.
Language
English
Position
PROFESSOR | Environmental Medicine
Multi-Disciplinary Training Areas
Neuroscience [NEU]
Education
BA, Loyola University Chicago
MA, University of Nebraska at Omaha
MPH, Columbia University
PhD, Columbia University
Awards
2011
Prenatal exposure to a mixture of endocrine disrupting compounds and child neurodevelopment
NIEHS
Research
- The Programming Research in Obesity, Growth, Environment and Social Stressors Study (PROGRESS) is collaboration between Icahn School of Medicine at Mount Sinai, University of Michigan and the National Institute of Public Health in Mexico City. The study consists of mother-dyad pairs enrolled during pregnancy and followed through early adolescence. PROGRESS uses state of the art methods in social science, exposure science, epidemiology and toxicology to assess trans disciplinary risk factors impacting neurodevelopment. Dr. Horton recently completed a pilot study to collect structural and functional MRI data from 20 PROGRESS subjects at the Center for Medical Imaging and Instrumentation (Ci3M). Ongoing work examines associations between early life exposures, structural and functional neuroimaging phenotypes and child behavior, emotional regulation, and cognition.
Publications
Selected Publications
- The Chemical Exposome on Ovarian Aging in Adult Women: a Narrative Review. Lauren M. Petrick, Lauren A. Wise, Elena Colicino, Megan K. Horton, Jaron Rabinovici, Tzipora Strauss, Batya Sarna, Liat Lerner-Geva, Michal A. Elovitz, Rosalind J. Wright, Andrea A. Baccarelli, Ronit Machtinger. Current Pollution Reports
- Childhood Pb-induced cognitive dysfunction: structural equation modeling of hot and cold executive functions. Jamil M. Lane, Shelley H. Liu, Vishal Midya, Cecilia S. Alcala, Shoshannah Eggers, Katherine Svensson, Sandra Martinez-Medina, Megan K. Horton, Roberta F. White, Martha M. Téllez-Rojo, Robert O. Wright. Journal of Exposure Science and Environmental Epidemiology
- BrainAgeNeXt: Advancing brain age modeling for individuals with multiple sclerosis. Francesco La Rosa, Jonadab Dos Santos Silva, Emma Dereskewicz, Azzurra Invernizzi, Noa Cahan, Julia Galasso, Nadia Garcia, Robin Graney, Sarah Levy, Gaurav Verma, Priti Balchandani, Daniel S. Reich, Megan Horton, Hayit Greenspan, James Sumowski, Merixtell Bach Cuadra, Erin S. Beck. Imaging Neuroscience