
Melissa J Nirenberg, MD, PhD
About Me
Melissa J. Nirenberg, MD, PhD, FAAN, is a Professor of Neurology at the Icahn School of Medicine at Mount Sinai, where she is involved in research and teaching at Mount Sinai Hospital and clinical practice in movement disorders at the James J. Peters VA Medical Center. Her research interests include non-motor manifestations of Parkinson’s disease, behavioral complications of dopamine agonist therapy, and clinicopathological and genetic studies of patients with neurodegenerative disorders. She is known for her discovery of dopamine agonist withdrawal syndrome (DAWS), a severe drug withdrawal syndrome that can occur when patients taper a specific class of medications used for treatment of Parkinson’s disease, restless legs syndrome, and other disorders.
Dr. Nirenberg pursued her undergraduate education at Yale University, graduating magna cum laude with Distinction in English. She subsequently received her MD and a PhD in neuroscience from the Tri-Institutional MD-PhD program at Weill Cornell, where she was recognized with awards for the highest achievement in the graduating class in both medicine and pediatrics. After medical school, Dr. Nirenberg completed a residency in Neurology at the University of California, San Francisco, followed by a fellowship in Movement Disorders at Columbia University Medical Center. She is a recipient of several prestigious teaching awards, and previously served as Associate Director of the Tri-Institutional MD-PhD Program at Weill Cornell, and more recently as Associate Director of the NYU Neurology Residency program. She is a fellow of the American Academy of Neurology, and a member of the Parkinson Study Group and International Parkinson and Movement Disorder Society.
Language
English
Position
PROFESSOR | Neurology
Clinical Focus
- Botulinum Toxin Injections
- Cervical Dystonia
- Chorea
- Dystonia
- Hemifacial Spasm
- Movement Disorders
- Parkinson's Disease
- Restless Legs Syndrome
- Tremor
- Wilson's Disease
Education
MD, PhD, Weill Cornell Medicine
Movement Disorders Fellowship, Columbia University Medical Center
Neurology Residency, University of California, San Francisco
Publications
Selected Publications
- Genome-Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology. Kathryn Step, Carlos F. Hernández, Marzieh Khani, Esraa Eltaraifee, Ana Jimena Hernández-Medrano, Pin Jui Kung, Miriam Ostrožovičová, Alexandra Zirra, Eduardo Pérez-Palma, Niccolò E. Mencacci, Ignacio J. Keller Sarmiento, Huw R. Morris, Ignacio F. Mata, Juliana Acosta-Uribe, Zih Hua Fang, Sara Bandres-Ciga, Yasser Mecheri, Bouchetara Mohamed Sofiane, Benhassine Traki, Emilia Mabel Gatto, Marcelo Kauffman, Federico Capparelli, Maria Valentina Muller, Marcela Susana Tela, Dario Sergio Adamec, Cesar Avila, Samson Khachatryan, Zaruhi Tavadyan, Mariam Isayan, Claire Shepherd, Kishore Kumar, Melina Ellis, Miguel Rentería, Sulev Koks, Simon Rowel, Dennis Yeow, Carolyn Sue, Victor Ocampo, Christine Wools, Keren Aliza Weiss, Sue Faye Siow, Ryan Davis, Amanda Willis, Steven He, Robert Arthur Wilcox, Denise Howting, Jack David Price, Ruth Walker, Melissa Nirenberg, Rachel Saunders-Pullman. Movement Disorders
- Basic Science and Pathogenesis. Grace A. Selecky, Kristen R. Whitney, Margaret M. Krassner, Alessandra Cervera, Claudia De Sanctis, Victoria Flores Almazan, Sean Thomas Delica, Soong Ho Kim, Kurt W. Farrell, Thomas D. Christie, Megan A. Iida, Lily Sarrafha, Gustavo Parfitt, Ruth H. Walker, Melissa J. Nirenberg, Giulietta M. Riboldi, Steven J. Frucht, Tim Ahfeldt, Sally Temple, John F. Crary. Alzheimer's and Dementia
- Correction to: Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes (Nature Communications, (2024), 15, 1, (7880), 10.1038/s41467-024-52025-x). Kurt Farrell, Jack Humphrey, Timothy Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa, Vishakha Patil, Wan Ping Lee, Amanda B. Kuzma, Otto Valladares, Laura B. Cantwell, Hui Wang, Ashvin Ravi, Claudia De Sanctis, Natalia Han, Thomas D. Christie, Robina Afzal, Shrishtee Kandoi, Kristen Whitney, Margaret M. Krassner, Hadley Ressler, Soong Ho Kim, Diana Dangoor, Megan A. Iida, Alicia Casella, Ruth H. Walker, Melissa J. Nirenberg, Alan E. Renton, Bergan Babrowicz, Giovanni Coppola, Towfique Raj, Günter U. Höglinger, Ulrich Müller, Lawrence I. Golbe, Huw R. Morris, John Hardy, Tamas Revesz, Tom T. Warner, Zane Jaunmuktane, Kin Y. Mok, Rosa Rademakers, Dennis W. Dickson, Owen A. Ross, Li San Wang, Alison Goate, Gerard Schellenberg, Daniel H. Geschwind, Justo García de Yebenes, Fairlie Hinton, John F. Crary. Nature Communications
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Nirenberg has not yet completed reporting of Industry relationships.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.