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Mone Zaidi, MD, PhD
Endocrine, Diabetes and Bone Diseases (Endocrinology)
About Me
Mone Zaidi graduated in medicine from King George’s Medical College, India, and trained clinically at the Hammersmith Hospital, London, under the tutelage of Professor Iain MacIntyre, FRS, who discovered calcitonin. After obtaining a PhD and MD from the University of London, Dr. Zaidi held faculty appointments for over 8 years, before he was recruited to Mount Sinai School of Medicine as Professor of Medicine and Founding Director of The Mount Sinai Bone Program. He is now Director of Mount Sinai’s Center for Translational Medicine and Pharmacology and was recently appointed as Deputy Editor for eLife where he is responsible for the medicine section of the journal.
Dr. Zaidi has made groundbreaking discoveries on mechanisms of skeletal homeostasis in health and disease. These studies, spanning over 30 years, included the first description of calcium sensing in the osteoclast and the discovery that locally released nitric oxide acts to suppress bone cells. In 2003, Zaidi’s group published the first evidence for a pituitary–bone axis, a breakthrough in physiology in which pituitary hormones could affect the skeleton directly. In recent groundbreaking papers in Nature, he found that inhibiting FSH not only increased bone mass, but also reduced body fat and neurodegeneration--in essence, laying a firm foundation for a single anti-FSH agent to treat osteoporosis, obesity and Alzheimer’s disease.
The corpus of work relating FSH to body fat was selected by Nature Medicine as one of eight “Notable Advances” in biomedicine for 2017 and was editorialized in the New York Times. Constituting a total of over 450 publications in journals, including Cell, Nature and PNAS, Zaidi’s research has been funded continuously by the NIH. He has also Chaired multiple Study Sections for the NIH and the Department of Veterans Affairs He was elected to the Association of American Physicians, Interurban Clinical Club of which he is President, the Practitioners’ Society (the oldest medical society in the U.S.) and the Association of Professors of Medicine. Dr. Zaidi was made Master of the American College of Physicians, received the Harrington Scholar–Innovator Award, was elected as Fellow of the American Association of Advancement of Science, and is recipient of three honorary doctorates.
Language
English
Position
PROFESSOR | Medicine, Endocrinology, Diabetes and Bone Disease, PROFESSOR | Pharmacological Sciences, PROFESSOR | Geriatrics and Palliative Medicine
Hospital Affiliations
- Mount Sinai Queens
- The Mount Sinai Hospital
Research Topics
Bone Biology, Bone Metabolism, Genetics, Hormones, Neuro-degeneration/protection, Obesity, Osteoporosis, Skeletal Biology
Multi-Disciplinary Training Areas
Genetics and Genomic Sciences [GGS]
Clinical Focus
- Hyperparathyroidism
- Osteoporosis
- Paget's Disease of Bone
- Vitamin D Deficiency
Education
MD, King Georges Medical University
MD, University of London
Residency, Endocrinology, Diabetes and Metabolism
Hammersmith Hospital
Certifications
American Board of Internal Medicine
Awards
2024
Foreign Member
Academia Europaea
2023
2023 AAIM Special Recognition Award
Alliance of Academic Internal Medicine
2023
Doctor of Science (ScD) Honoris Causa
University of Connecticut
2022
Austrian International Research Prize
Austria’s Agency for Education and Internationalisation (OeAD)
2022
Doctor of Science Honoris Causa
King Georges Medical College
2022
Fellow
National Academy of Inventors
2022
Honorary Fellowship
British Pharmacological Society
2020
Deputy Editor for Medicine
eLife Journal
2019
Fellow
American Society for Bone and Mineral Research (Class of 2019)
2019
The J. Lester Gabrilove Award
Mount Sinai Alumnus Association
2019
Fellow
American Association for the Advancement of Science
2018
Foreign Fellow
National Academy of Sciences of India
2018
Honorary Member
Tinsley Randolph Harrison Society, Vanderbilt
2018
Harrison Society Visiting Professor
Vanderbilt University
2017
Doctorate of Science Honoris Causa
Amity University, India
2017
Mastership in the American College of Physicians (MACP)
American College of Physicians (MACP)
2017
Harrington Scholar- Innovator Award
Harrington Discovery Institute
2016
The Practitioners Society
New York (by invitation, est. 1882)
2016
President
Interurban Clinical Club
2016
Faculty Council Award for Academic Excellence
Mount Sinai
2014
Honorary Member
International Chinese Musculoskeletal Research Society
2014
Association of Professors of Medicine (by nomination)
2013
Doctor of Science Honoris Causa
Postgraduate Institute of Medical Sciences, India
2010
Honorary Doctor of Medicine (Laurea Honoris Causa),
University of Bari
2010
Sreebny Distinguished Lecture,
State University of New York, Stony Brook,
2009
The Marookian Lecture
University of Pennsylvania
2008
Kramer Visiting Professor
Dartmouth Medical School
2008
Sibte H. Zaidi Memorial Oration
Indian Institute of Toxicology Research, India
2006
Highlight Speaker
NIA Council
2005
Scientific Director and Chair
New York Skeletal Biology and Medicine Conferences Highlight Speaker, NIA Council
2005
Invited Speaker
Japanese Bone and Mineral society
2004
Member
Association of American Physicians
2003
Committee Member
Department of Veterans Affairs Endocrine Merit Review Committee
2002
Research Excellence Award - Department of Veterans Affairs
NIH Orthopedics and Musculoskeletal Study Section
2002
Eweson Lecturer
Cambridge Philosophical Society
2001
National Scientific Advisory Council & Research Committee
American Federation for Aging Research
2000
Advisory Group Member
Department of Veterans Affairs Medical Research Advisory Group
2000
Foster Lecture
University of Cambridge
2000
Member
American Society for Clinical Investigation
1998
Fellow
Royal College of Pathologists
1997
Fellow
Royal College of Physicians
1995
Fellow
Institute of Biologists of England
1995
Fellow
Tata Memorial Scholar, London
1988
Lecturer
Nuffield Award for Science Lecturer, London
1985
Award
Sir Edmund Davis Scholarship
1983
Award
Stott Gold Medal in Pathology
Member
Association of Osteobiology, Interurban Clinical Club, Councilor
Research
Dr. Zaidi has made groundbreaking discoveries on mechanisms of skeletal homeostasis in health and disease. These studies, spanning over 30 years, included the first description of calcium sensing in the osteoclast and the discovery that locally released nitric oxide acts to suppress bone cells. In 2003, Zaidi’s group published the first evidence for a pituitary–bone axis, a breakthrough in physiology in which pituitary hormones could affect the skeleton directly. In recent groundbreaking papers in Nature, he found that inhibiting FSH not only increased bone mass, but also reduced body fat and neurodegeneration--in essence, laying a firm foundation for a single anti-FSH agent to treat osteoporosis, obesity and Alzheimer’s disease.
Insurance Information
Accepted insurance may vary by the doctor’s office location. Please contact the office directly to obtain the most up-to-date insurance information.
- 1199 SEIU
- AETNA - Commercial
- AETNA - Medicare
- Affinity Medicaid-Medicare-Essential Exchange
- CIGNA Healthcare
- Centivo
- Elderplan
- EmblemHealth - GHI-PPO
- EmblemHealth - HIP
- EmblemHealth - HIP-Medicaid
- EmblemHealth - HIP-Medicare
- Fidelis Health Care
- HealthFirst Medicare
- Magnacare-Health Care
- Medicare - NJ
- Medicare - NY
- Metroplus
- Multiplan PHCS
- NJ Medicaid
- NY Medicaid
- Oscar
- Oxford - Freedom and Liberty
- Partners Health Plan
- Senior Whole Health
- United Health Care - Commercial
- United Health Care - Empire Plan
- United Health Care - Oxford Care
- United Health Care - Top Tier
- VNSNY Choice Medicare
- VillageCareMax
- WellCare Health Plan
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.
Publications
Selected Publications
- Higher FSH Level Is Associated with Increased Risk of Incident Hip Fracture in Older Adults, Independent of Sex Hormones. Eileen H. Koh, Susan K. Ewing, Sigurdur Sigurdsson, Vilmundur Gudnason, Trisha F. Hue, Eric Vittinghoff, Claes Ohlsson, Åsa Tivesten, Louise Grahnemo, Tony Yuen, Mone Zaidi, Clifford J. Rosen, Ann V. Schwartz, Anne L. Schafer. Journal of Clinical Endocrinology and Metabolism
- Gene–dose-dependent reduction of Fshr expression improves spatial memory deficits in Alzheimer’s mice. Funda Korkmaz, Steven Sims, Fazilet Sen, Farhath Sultana, Victoria Laurencin, Liam Cullen, Anusha Pallapati, Avi Liu, Ronald Chen, Satish Rojekar, Georgii Pevnev, Uliana Cheliadinova, Darya Vasilyeva, Guzel Burganova, Anne Macdonald, Mansi Saxena, Ki Goosens, Clifford J. Rosen, Orly Barak, Daria Lizneva, Anisa Gumerova, Keqiang Ye, Vitaly Ryu, Tony Yuen, Tal Frolinger, Mone Zaidi. Molecular Psychiatry
- Targeting FSH for osteoporosis, obesity, and Alzheimer's disease. Funda Korkmaz, Judit Gimenez-Roig, Farhath Sultana, Victoria Laurencin, Fasilet Sen, Liam Cullen, Steven Sims, Anusha Pallapati, Satish Rojekar, Guzel Burganova, Georgii Pevnev, Uliana Cheliadinova, Darya Vasilyeva, Ofer Moldavski, Tal Frolinger, Anisa Gumerova, Orly Barak, Vitaly Ryu, Daria Lizneva, Keqiang Ye, Anne Schafer, Clifford J. Rosen, Tony Yuen, Se Min Kim, Mone Zaidi. Trends in Molecular Medicine
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Below are financial relationships with industry reported by Dr. Zaidi during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- Gerson Lehrman Group
- Rani Pharmaceuticals
- Cannacord
- Guidepoint Global, LLC.
- Indiana University
- Relation Therapeutics
- Blackstone
Editorial Services
- eLife
- National Institutes of Health (NIH)
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.