Nan Yang | Mount Sinai - New York
Nan Yang

Nan Yang, PhD

About Me

Dr. Yang is an Assistant Professor of Neuroscience, a member at Black Family Stem Cell Institute, Friedman Brain Insititute and Ronald M. Loeb Center for Alzheimer's Disease. Her laboratory is focused on the understanding of the molecular programs that control the development of distinct cell types in the brain and the developing of approaches using human stem cells combined of gene editing to advance our knowledge of the fundamental processes underlying human neural development in normal and pathological conditions. They use in vitro 2D and 3D models to decipher the phenotypic consequences of disease-causing mutations in human neurons and other neural lineages as well as the development of novel therapeutic gene targeting and cell transplantation-based strategies for numerous neuropsychiatric disorders.

Learn more about the Yang Laboratory.

Language
English
Position
ASSOCIATE PROFESSOR | Neuroscience
Research Topics

Alzheimer's Disease, Autism, Cell Biology, Cellular Differentiation, Chromatin, Developmental Neurobiology, Epigenetics, Epigenomics, Gene Regulation, Gene editing, Induced pluripotent stem cells, Molecular Biology, Myelination, Neuroscience, Parkinson's Disease, Psychiatry, Regeneration, Reprogramming, Schizophrenia, Stem Cells, Synapses, Synaptogenesis

Multi-Disciplinary Training Areas

Development Regeneration and Stem Cells [DRS], Neuroscience [NEU]

Education

Exchange student, University of California, San Francisco
PhD, Fundan University
Postdoctoral, Stanford University

Awards

2014

NARSAD Young Investigator

Research

One of the most intriguing applications of human pluripotent stem cells is the possibility to recapitulate and study key aspects of human brain development. Our group team up with the Seaver Autism Center at Mount Sinai to investigate the changes caused by autism associated rare mutations at cellular and molecular levels in multiple brain regions using 3D brain organoid models and in different neuronal types with particular interests on epigenetic modifications and synaptic functions using induced neurons.

Locations