About Me
PJ Maglione, MD, PhD is a physician-scientist in the Division of Clinical Immunology of the Department of Medicine. His research efforts in the areas of primary antibody deficiency and B cell biology have been supported by the Thrasher Research Fund, Clinical Immunology Society, Jeffrey Modell Foundation, and Primary Immune Deficiency Treatment Consortium. Dr. Maglione is board-certified by the American Board of Internal Medicine and the American Board of Allergy and Immunology, sees patients at the clinical immunology faculty practice, and supervises a weekly teaching clinic with the fellows in Mount Sinai's Allergy/Immunology training program. He also lectures to graduate and medical students in the area of B cell biology and is an instructor in the medical school immunology course.
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ADJUNCT ASSISTANT PROFESSOR | Medicine, Clinical ImmunologyAbout Me
PJ Maglione, MD, PhD is a physician-scientist in the Division of Clinical Immunology of the Department of Medicine. His research efforts in the areas of primary antibody deficiency and B cell biology have been supported by the Thrasher Research Fund, Clinical Immunology Society, Jeffrey Modell Foundation, and Primary Immune Deficiency Treatment Consortium. Dr. Maglione is board-certified by the American Board of Internal Medicine and the American Board of Allergy and Immunology, sees patients at the clinical immunology faculty practice, and supervises a weekly teaching clinic with the fellows in Mount Sinai's Allergy/Immunology training program. He also lectures to graduate and medical students in the area of B cell biology and is an instructor in the medical school immunology course.
Language
Position
ADJUNCT ASSISTANT PROFESSOR | Medicine, Clinical ImmunologyAbout Me
PJ Maglione, MD, PhD is a physician-scientist in the Division of Clinical Immunology of the Department of Medicine. His research efforts in the areas of primary antibody deficiency and B cell biology have been supported by the Thrasher Research Fund, Clinical Immunology Society, Jeffrey Modell Foundation, and Primary Immune Deficiency Treatment Consortium. Dr. Maglione is board-certified by the American Board of Internal Medicine and the American Board of Allergy and Immunology, sees patients at the clinical immunology faculty practice, and supervises a weekly teaching clinic with the fellows in Mount Sinai's Allergy/Immunology training program. He also lectures to graduate and medical students in the area of B cell biology and is an instructor in the medical school immunology course.
Language
Position
ADJUNCT ASSISTANT PROFESSOR | Medicine, Clinical ImmunologyAwards
2013
Senior Fellowship Award
Clinical Immunology Society
2013
Clemens von Pirquet Award
American College of Allergy, Asthma, and Immunology
2012
Early Career Award
Thrasher Research Fund
Research
T-independent antibody responses against bacteria
Current vaccines against bacteria are limited by serotype specificity and lack of long-term efficacy. With expanding resistance against antibiotics, new strategies for augmenting antibacterial immunity are clearly needed. Using a "bedside-to-bench" research approach, Dr. Maglione is studying human primary immunodeficiencies that impair the ability to produce antibodies against bacteria in order to understand the biological determinants of successful immunity against these pathogens. The goal of this work is to translate new information about how humans make antibodies against bacteria into novel strategies for immune therapies and vaccines. Particular attention is paid to "T-independent" antibody responses, as they are quite potent against bacteria but have not been extensively studied outside of animal models.
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Maglione during 2021 and/or 2022. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Scientific Advisory Board:
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
