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Accepting New PatientsPaula J Busse, MD
Allergy and Immunology
Department of Medicine - Allergy & Immunology
212-241-0764
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- Industry Relationships
About Me
Paula J. Busse MD is an Associate Professor in the Department of Medicine, Division of Clinical Immunology. She received her undergraduate education at Wellesley College and her medical degree from the University of Rochester. She completed her medical residency training in Internal Medicine and her post-doctorate training in Allergy and Immunology at the Mount Sinai School of Medicine, where she also completed a graduate clinical research training program. Her clinical and research areas of interest are asthma in older patients and treatment of hereditary angioedema. Dr. Busse is funded by the National Institutes of Health and several foundation grants. She is active in the American Academy of Allergy, Asthma and Immunology, giving lectures at national and local meetings and is involved in several of its committees. She has been elected to the Hereditary Angioedema Association Scientific Medical Advisory Board. She has been a small group discussion leader for the first-year medical student basic immunology course for several years.
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Brooklyn
- Mount Sinai Queens
- The Mount Sinai Hospital
- Mount Sinai Morningside and Mount Sinai West
About Me
Paula J. Busse MD is an Associate Professor in the Department of Medicine, Division of Clinical Immunology. She received her undergraduate education at Wellesley College and her medical degree from the University of Rochester. She completed her medical residency training in Internal Medicine and her post-doctorate training in Allergy and Immunology at the Mount Sinai School of Medicine, where she also completed a graduate clinical research training program. Her clinical and research areas of interest are asthma in older patients and treatment of hereditary angioedema. Dr. Busse is funded by the National Institutes of Health and several foundation grants. She is active in the American Academy of Allergy, Asthma and Immunology, giving lectures at national and local meetings and is involved in several of its committees. She has been elected to the Hereditary Angioedema Association Scientific Medical Advisory Board. She has been a small group discussion leader for the first-year medical student basic immunology course for several years.
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Brooklyn
- Mount Sinai Queens
- The Mount Sinai Hospital
- Mount Sinai Morningside and Mount Sinai West
About Me
Paula J. Busse MD is an Associate Professor in the Department of Medicine, Division of Clinical Immunology. She received her undergraduate education at Wellesley College and her medical degree from the University of Rochester. She completed her medical residency training in Internal Medicine and her post-doctorate training in Allergy and Immunology at the Mount Sinai School of Medicine, where she also completed a graduate clinical research training program. Her clinical and research areas of interest are asthma in older patients and treatment of hereditary angioedema. Dr. Busse is funded by the National Institutes of Health and several foundation grants. She is active in the American Academy of Allergy, Asthma and Immunology, giving lectures at national and local meetings and is involved in several of its committees. She has been elected to the Hereditary Angioedema Association Scientific Medical Advisory Board. She has been a small group discussion leader for the first-year medical student basic immunology course for several years.
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Brooklyn
- Mount Sinai Queens
- The Mount Sinai Hospital
- Mount Sinai Morningside and Mount Sinai West
Clinical Focus
- Allergic Asthma
- Allergic Contact Dermatitis
- Allergic Cough
- Allergic Rhinitis
- Allergy Injections
- Allergy Testing
- Anaphylaxis
- Angioedema
- Asthma
Show More
- Allergic Asthma
- Allergic Contact Dermatitis
- Allergic Cough
- Allergic Rhinitis
- Allergy Injections
- Allergy Testing
- Anaphylaxis
- Angioedema
- Asthma
- Contact Dermatitis
- Cough
- Drug Allergy/Reactions
- Eczema
- Eosinophilia
- Food Allergy
- Hay Fever
- Hives
- Insect Allergy
- Nasal Polyp
- Pulmonary Function Tests
- Sinusitis
Education
MD, University of Rochester School of Medicine & Dentistry
Residency, Internal Medicine
The Mount Sinai Hospital
Fellowship, Clinical Immunology
The Mount Sinai Hospital
Awards
2008
Allergy, Asthma and Immunology Education and Research Trust/Journal of Clinical Immunology Research Award
2003
Dr. Solomon Silver Award
Clinical Medicine (MSH)
2003
T. Franklin Williams Scholar Award
2002
ACAAI Young Faculty Award
New award
Research
Asthma in older patients
Asthma morbidity and mortality is highest in patients >65 years old, and underlying airway inflammation in this age group has not been characterized. In this laboratory, we have studied a model of asthma in aged mice and have investigated whether age alters modulation of airway inflammation. Presently, the laboratory is translating these studies to evaluate clinical characteristics of asthma in older patients and markers of inflammation in the airways of these patients. This knowledge will help to direct age-specific anti-inflammatory asthma therapy.
Hereditary Angioedema (HAE)
HAE is a rare disease which affects approximately 4,000 people in the US. Its symptoms include swelling of the face, airway, extremities and abdomen. If swelling involves the airways, it can be life-threatening. Our group has been involved in several clinical trials for new medications to treat HAE. In addition, the laboratory is presently studying mechanisms by whichestrogen can exacerbate HAE.
Selected publications
Zuraw BL, Banerji A, Bernstein JA, Busse PJ, Christiansn SC, Davis-Lorton M, Frank MM, Li HH, Lumry WR, Riedl M. US Hereditary Angioedema Association Medical Advisory Board 2013 Recommendation for the management of Hereditary Angioedema due to C1 Inhibitor deficiency. J Allergy and Clin Immunol: In Practice 2013; 1 (6): 458-467.
Birmingham JM, Patil S, Li XM, Busse PJ. The effect of oral tolerance on the allergic airway response in young and aged mice. J Asthma 2013: 50 (2): 122-32.
Busse PJ, Cohn RD, Salo PM, Zeldin DL. Characteristics of allergic sensitization among adult asthmatics >55 years: Results from the National Health and Nutrition Examination Survey 2005-2006. Ann Allergy Asthma Immunol 2013; 110 (4) 247-52.
Riedl MA, Hurewitz DS, Levy R, Busse PJ, Fitts D, Kalfus I. Nanofiltered C1 esterase inhibitor (human) for the treatment of acute attacks of hereditary angioedema: an open-label trial. Ann Allergy Asthma Immunol 2012; 108: 49-53.
Busse PJ, Lurshurchadia L, Sampson H, Halm EA, Wisnivesky J. Perennial allergen-specific immunoglobulin E levels among inner-city elderly asthmatics. J Asthma 2010; 47 (7): 781-5.
Zuraw BL, Busse PJ, White M, et al. Nanofiltered C1 Inhibitor Concentrate for treatment of hereditary angioedema. NEJM 2010; 363 (6): 513-22.
Busse PJ, Schofield B, Birmingham N, Yang N, Wen MC, Zhang T, Srivastava K, Li XM. The traditional Chinese Herbal Formula, ASHMI, inhibits allergic lung inflammation in antigen-sensitized and antigen-challenged aged mice. Ann Allergy Asthma Immunol 2010; 104 (3): 236-246.
Busse PJ, Zhang TF, Schofield B, Kilaru K, Patil S, Li XM. Decrease in airway mucous gene expression caused by treatment with anti-tumor necrosis factor alpha in a murine model of allergic asthma. Ann Allergy Asthma Immunol 2009; 103 (4): 295-303.
Busse PJ, Zhang, TF, Srivastava K, Schofield B, Li XM. Effect of ageing on pulmonary inflammation, airway hyperresponsiveness and T and B cell responses in antigen-sensitized and -challenged mice. Clin Exp Allergy 2007; 37 (9): 1392-1403.
Clinical trials
Anti IL-5 (Mepolizumab) treatment in hypereosinophilic syndrome
Consulting
CSL Behring, Viropharma/Shire, Dyax Corp, Gerson Lehrman Group
Locations
Insurance Information
Accepted insurance may vary by the doctor’s office location. Please contact the office directly to obtain the most up-to-date insurance information.
- Department of Medicine - Allergy & Immunology5 East 98th Street, 11th Floor, New York, NY, 10029
- 1199 SEIU
- AETNA - Commercial
- AETNA - Medicare
- Affinity Medicaid-Medicare-Essential Exchange
- AgeWell New York
- CIGNA Healthcare
- Centivo
- Elderplan
- EmblemHealth - GHI-PPO
- EmblemHealth - HIP
- EmblemHealth - HIP-Medicaid
- EmblemHealth - HIP-Medicare
- Empire Blue Cross Blue Shield - Commercial/Exchange
- Empire Blue Cross Blue Shield - Healthplus FKA Amerigroup Medicaid
- Empire Blue Cross Blue Shield - Medicare
- Fidelis Health Care
- HealthFirst Medicaid
- HealthFirst Medicare
- Horizon NJ
- Hotel Trades
- Magnacare-Health Care
- Medicare
- Metroplus
- Multiplan PHCS
- NY Medicaid
- Oxford - Freedom & Liberty
- Partners Health Plan
- Senior Whole Health
- United Health Care - Commercial
- United Health Care - Community Care Medicaid
- United Health Care - Empire Plan
- United Health Care - Oxford Care
- United Health Care - Top Tier
- VNSNY Choice Medicare
- VillageCareMax
- WellCare Health Plan
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.
Publications
Article:85
Review Article:16
Comment/Debate:4
Letter:5
Editorial:1
Chapter:2
Recent Artifacts
- The international WAO/EAACI guideline for the management of hereditary angioedema—The 2021 revision and update
- Prophylactic use of an anti-activated factor XII monoclonal antibody, garadacimab, for patients with C1-esterase inhibitor-deficient hereditary angioedema: a randomised, double-blind, placebo-controlled, phase 2 trial
- Long-term prevention of hereditary angioedema attacks with lanadelumab: The HELP OLE Study
- Specific Targeting of Plasma Kallikrein for Treatment of Hereditary Angioedema: A Revolutionary Decade
- The international WAO/EAACI guideline for the management of hereditary angioedema – The 2021 revision and update
- The Relationship Between Post-Traumatic Stress Disorder and Self-Management Behaviors in World Trade Center Workers with Asthma
- Cognition, symptom perception, and medication non-adherence in older adults with asthma
- Consensus on treatment goals in hereditary angioedema: A global Delphi initiative
- Effectiveness of lanadelumab for preventing hereditary angioedema attacks: Subgroup analyses from the HELP study
- Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children
Patient Experience Rating
The Patient Experience Star Rating reflects our patients’ perception of how well their Mount Sinai provider communicated with them during an office visit. The Star Rating is based on patient responses to three questions on a patient experience survey, a standardized questionnaire sent to verified patients and distributed by a third party vendor, Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score.
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Busse during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting:
- Regeneron Pharmaceuticals
- WebMD
- CVS Health
- Takeda
- United Expert Holdings-Hinkley Allen
- Medscape
- Novartis
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.