
Peter H Rudebeck, PhD
About Me
Dr Rudebeck joined the department of Neuroscience at the Icahn School of Medicine at Mount Sinai in 2014 as an Assistant Professor. His training and background are in neuropsychology and neurophysiology. He obtained his PhD in Experimental Psychology from the University of Oxford, where he investigated the role of the prefrontal cortex in emotion, social behavior and decision-making. Prior to joining the faculty at Mount Sinai, Dr Rudebeck was a Research Fellow at the National Institute of Mental Health (NIMH), in Bethesda, Maryland. While at the NIMH, his research focused on how interaction between the prefrontal cortex and other parts of the brain, such as the amygdala, contributes to emotion and cognition. At the Icahn School of Medicine, Dr Rudebeck’s lab will investigate the neural systems involved in emotion and decision-making using a combination of behavioral, neurophysiology and interference techniques.
Language
English
Position
PROFESSOR | Neuroscience, PROFESSOR | Psychiatry, PROFESSOR | Graduate Education
Research Topics
Behavior, Bioinformatics, Brain, Cerebral Cortex, Cognitive Neuroscience, Computational Neuroscience, Electrophysiology, Memory, Motor Neuron, Neural Networks, Neurophysiology, Neuroscience, Prefrontal Cortex, Systems Neuroscience
Multi-Disciplinary Training Areas
Neuroscience [NEU]
Education
PhD, University of Oxford
Awards
2017
Career Development Award
Society for Neuroscience
2016
NIMH BRAINS Award
NIMH
2009
Julius Axelrod Memorial Fellowship
National Insitute of Mental Health
Research
In our daily lives we often encounter both pleasurable and aversive situations, which heighten our emotional state and affect cognition. The ability to flexibly regulate our emotions in response to such events is essential for adapting to our environment and, ultimately, for our mental health. Many forms of mental illness involve dysfunction in the neural systems that regulate affective processing. The limbic system, which includes parts of the prefrontal cortex and medial temporal lobe, is critical for regulating emotions and plays an essential role in cognition. The main focus of the Rudebeck lab is to understand how the limbic system, specifically the amygdala and ventromedial prefrontal cortex, contribute to emotional regulation and decision-making. To do this, we use a combination of behavioral, autonomic, neurophysiological and lesion approaches in animal models.
Visit Peter Rudebeck's Laboratory of Neurobiology of Emotion & Cognition for more information.
Publications
Selected Publications
- Circuit-Based Approaches to Understanding the Anterior Cingulate Cortex (ACC). Daulton C. Myers, Joseph Simon, Jungmin Oh, Katherine E. Kabotyanski, Satoka Fujimoto, Desmond J. Oathes, Peter H. Rudebeck, Ken Ichi Amemori, Sameer A. Sheth, Julie L. Fudge. Journal of Neuroscience
- Consistent Hierarchies of Single-Neuron Timescales in Mice, Macaques, and Humans. Zachary R. Zeisler, Marques Love, Ueli Rutishauser, Frederic M. Stoll, Peter H. Rudebeck. Journal of Neuroscience
- Pharmacological Modulation of Dopamine Receptors Reveals Distinct Brain-Wide Networks Associated with Learning and Motivation in Nonhuman Primates. Atsushi Fujimoto, Catherine Elorette, Satoka H. Fujimoto, Lazar Fleysher, Peter H. Rudebeck, Brian E. Russ. Journal of Neuroscience
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Rudebeck did not report having any of the following types of financial relationships with industry and other outside entities during 2025 and/or 2026: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.