Publications:35
Pin-Xian Xu, PhD
About Me
Language
English
Position
PROFESSOR | Genetics and Genomic Sciences, PROFESSOR | Stem Cell Biology And Regenerative Medicine
Research Topics
Auditory, Developmental Biology, Epigenetics, Gene Regulation, Genetics, Genomics, Human Genetics and Genetic Disorders, Inner Ear, Kidney, Knockout Mice, Neuroscience, Organogenesis, Protein Phosphatases, Regeneration
Multi-Disciplinary Training Areas
Development Regeneration and Stem Cells [DRS], Genetics and Genomic Sciences [GGS]
Education
PhD, The Graduate University for Advanced Studies, Japan
Postdoctoral fellow, Harvard Medical School/Brigham & Women's Hospital
Awards
2007
Member
NIH Scientific Review Group UKGD
2000
Research Award
National Science Foundation
1999
Recipient of 50th Anniversary Program for Scholars in Medicine Fellowship
Harvard Medical School
1997
Individual National Research Service Award
National Eye Institute/NIH
Research
Pin-Xian Xu’s laboratory studies regulatory networks that drive organogenesis. In particular, our lab is interested in the general question of how cell diversity in our body is created. A major focus of our research is auditory and renal development and maintenance, where we seek to identify the pathways by which EYA1 drives a small group of progenitor cells to become functional sensory neurons and hair cells in the inner ear or nephrons in the kidney. For more detailed information, please consult our lab website.
Publications
Selected Publications
- Regulatory Networks Driving the Specification, Differentiation, and Diversification of Neurons in the Mouse Inner Ear. Gabriela Pavlinkova, Pin Xian Xu, Kathryn S.E. Cheah, Ebenezer N. Yamoah, Bernd Fritzsch. JARO - Journal of the Association for Research in Otolaryngology
- Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development. Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin Xian Xu. Frontiers in Cell and Developmental Biology
- The role of Eya1 and Eya2 in the taste system of mice from embryonic stage to adulthood. Ting Zhang, Pin Xian Xu. Frontiers in Cell and Developmental Biology
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Xu has not yet completed reporting of industry relationships or has no industry relationships to report.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.