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  • Treats Children & Adults

Rachel Miller, MD

Allergy and Immunology

Clinical Focus

Education

MD, New York University School of Medicine

Residency, Internal Medicine

Columbia University Irving Medical Center

Fellowship, Pulmonary and Critical Care Medicine

Columbia Presbyterian Medical Center

Fellowship, Allergy & Immunology

Columbia University Irving Medical Center

Certifications

American Board of Allergy & Immunology

Awards

2021

I. Leonard Bernstein, MD FAAAAI Memorial Lectureship at the AAAAI/ACAAI Joint Congress

2018

AAAAI Foundation and Sheldon L. Spector, MD FAAAAI Memorial Lectureship at the AAAAI/ACAAI Joint Congress for delivering the talk “Epigenetic Changes Ascribed to Pollutant Exposures”

2017

Thomas A. Neff Lecturer at the Thomas L. Petty Aspen Lung Conference, 60th Annual Meeting,

2015

Samberg Scholar in Children’s Health

1999

Florence and Herbert Irving Clinical Research Career Award

1990

Eve Flechner Award in Internal Medicine

Research

We are interrogating novel biomarkers that capture responses to multiple environmental stressors, and are highly sensitive to the dynamics of dysregulation, on lung function and airway inflammation. Mitochondrial (mt) DNA lacks protective histones and possesses diminished DNA repair mechanisms, rendering it more susceptible than the nuclear genome to damage by reactive oxygen species (ROS), interrupting redox homeostasis, and causing inflammation. Our group and others have shown that exposure to air pollution and allergens increases intracellular levels of ROS in mitochondria. The ensuing mtDNA damage increases its quantity or content. Urban exposures also may alter methylation at key mitochondrial replication and transcriptional control regions. Asthmatics may be more susceptible. Mitochondrial DNA damage can reverse, possibly more readily than other plasma biomarkers of oxidative stress. Our objective is to elucidate the dynamic interplay between reductions in multiple inflammatory urban exposures, attributable changes in mtDNA content and methylation, and improvements in pediatric asthma outcomes over time. We intend to capture the pivotal role of novel mt biomarkers in measuring the dynamic biological responses following induction and remediation of oxidative damage, triggered by a child's changing personal environment. Results could direct more effective personalized biomarker-guided therapy or intervention, including environmental remediation, pathway inhibitors, or dietary interventions, for children with persistent asthma, and for all children exposed to an urban environment.

Insurance Information

Accepted insurance may vary by the doctor’s office location. Please contact the office directly to obtain the most up-to-date insurance information.

Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).

Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.

Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.

Patient Experience Star Ratings and Comments

The Patient Experience Star Rating reflects our patients’ perception of how well their Mount Sinai provider communicated with them during an office visit. The Star Rating is based on patient responses to three questions on a patient experience survey, a standardized questionnaire sent to verified patients and distributed by a third party vendor, Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score.

Care Provider’s Explanation

Care Provider’s Concern

Likelihood to Recommend Care Provider

Outstanding experience

Experiences are good and confidence-inspiring in a NYC doctor's office are rare. I felt very lucky to be in Dr Miller's care

Dr. Miller is ALWAYS thorough and reads up on my prior health Issues In advance of my appt. Her summary notes are clear and concise. She lays out an understandable road map of things I need to follow up on. She is caring and inquisitive and determined to seek resolutions of all health issues related to Immunology. I am very grateful she Is part of my care team.

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