Raymund Yong, MD, Associate Professor of Neurosurgery, specializes in the diagnosis and treatment of malignant and benign brain tumors, and he also has an interest in general disorders of the brain and spine. He has subspecialty fellowship training in the removal of infiltrative tumors from eloquent regions of the brain—including the areas for language and motor function—using computer-guided navigation, brain mapping techniques, and awake surgery. Dr. Yong also has a strong research interest in using new insights on how gliomas originate and evolve through time to develop innovative treatment strategies for his patients. He has received several national and international awards for his work in stem cells and cancer genetics. He also collaborates with other investigators and institutions to enroll patients in clinical trials studying the latest experimental treatments.
Dr. Yong’s laboratory is interested in characterizing the initial genetic and epigenetic events that give rise to malignant brain tumors. Additionally, the lab seeks to understand how current standard treatment regimes, such as radiation therapy and chemotherapy, interact with the cancer genome to influence the way in which tumor cells change through time and diversify in different compartments in the brain. The inherent genetic instability of cancer cells and their resulting adaptive abilities is a major reason why gliomas inevitably recur following treatment and are ultimately fatal. A greater understanding of the cancer genome as a dynamic, three-dimensional structure will lead to the development of new strategies that attempt to address cancer evolution directly.
Read about Dr. Yong's patient who went "Back to Bowling from Brain Surgery."
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