
Robert S Krauss, PhD
About Me
Endowed Chair, Mount Sinai Professor in Cell Biology
Professor, Department of Cell, Developmental, and Regenerative Biology
Professor, Department of Oncological Sciences
Member, Institute for Regenerative Medicine and Black Family Stem Cell Institute
Member, Mindich Child Health and Development Institute
Member, Tisch Cancer Institute
For more information, please visit the Krauss Laboratory website.
Language
Position
Research Topics
Cell Adhesion, Cell Biology, Cellular Differentiation, Cytoskeleton, Developmental Biology, Developmental Neurobiology, Genetics, Human Genetics and Genetic Disorders, Knockout Mice, Muscle Cells, Muscular Dystrophy, Protein Kinases, Signal Transduction, Stem Cells
Multi-Disciplinary Training Areas
Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS]
Download the CVAbout Me
Endowed Chair, Mount Sinai Professor in Cell Biology
Professor, Department of Cell, Developmental, and Regenerative Biology
Professor, Department of Oncological Sciences
Member, Institute for Regenerative Medicine and Black Family Stem Cell Institute
Member, Mindich Child Health and Development Institute
Member, Tisch Cancer Institute
For more information, please visit the Krauss Laboratory website.
Language
Position
Research Topics
Cell Adhesion, Cell Biology, Cellular Differentiation, Cytoskeleton, Developmental Biology, Developmental Neurobiology, Genetics, Human Genetics and Genetic Disorders, Knockout Mice, Muscle Cells, Muscular Dystrophy, Protein Kinases, Signal Transduction, Stem Cells
Multi-Disciplinary Training Areas
Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS]
Download the CVEducation
PhD, University of North Carolina
Postdoc, Columbia University
Awards
2010
Editorial Board
Skeletal Muscle
2006
President
Society for Muscle Biology
2006
Editorial Board
Molecular and Cellular Biology
2004
Editorial Board
Journal of Cell Science
1999
Established Investigator Award
American Heart Association
1996
Career Scientist Award
Irma T. Hirschl Trust
Research
The Krauss lab is interested in regulation of cell adhesion and signal transduction pathways during embryonic development and tissue regeneration, and how such processes may go awry in disease. The lab has two major areas of focus.
First, we are interested in development and regeneration of skeletal muscle. We have identified multiprotein cell surface complexes that promote differentiation of skeletal muscle precursor cells in response to cell-cell contact and adhesion. We use a combination of approaches, including mouse genetics, cell biology and biochemistry to probe the biological functions and molecular mechanisms of such complexes in skeletal myogenesis. We have recently turned our attention to how specific cell adhesion molecules regulate the niche and activity of muscle stem cells during homeostasis and regeneration following injury.
We are also interested mechanisms whereby the Hedgehog signaling pathway regulates development of the midline of the forebrain and midface. Mutations in Hedgehog pathway genes are associated with the common and often devastating developmental defect holoprosencephaly (HPE). However, the clinical outcome of mutation carriers is extremely variable, and additional genetic or environmental factors are required for strong defects. Using mouse models of such interactions and functional analyses of human HPE-associated mutations, we aim to provide information on mechanisms of HPE that will be valuable for genetic counseling and preventive action.
For more information, please visit the Krauss Laboratory website.
Locations
Publications
Selected Publications
- Science at Sundance 2025Heightened Scrutiny, Sam Feder, director, 2025, 89 minutes.Life After, Reid Davenport, director, 2025, 99 minutes.How to Build a Library, Maia Lekow and Christopher King, directors, Circle and Square Productions, 2025, 103 minutes.SALLY, Cristina Costantini, director, National Geographic, 2024, 103 minutes.The Perfect Neighbor, Geeta Gandbhir, director, 2025, 96 minutes.Middletown, Jesse Moss and Amanda McBaine, directors, 2025, 111 minutes. Valerie Thompson, Gabrielle Kardon, Michael D. Shapiro, Paul L. Koch, Robert S. Krauss. Science
- When everything is a master regulator, nothing is. Robert S. Krauss, Michael Kyba. Molecular Biology of the Cell
- Endothelial cell signature in muscle stem cells validated by VEGFA-FLT1-AKT1 axis promoting survival of muscle stem cell. Mayank Verma, Yoko Asakura, Xuerui Wang, Kasey Zhou, Mahmut Ünverdi, Allison P. Kann, Robert S. Krauss, Atsushi Asakura. eLife