
Samuel Sidi, PhD
About Me
Language
English
Position
PROFESSOR | Stem Cell Biology And Regenerative Medicine, PROFESSOR | Medicine, Hematology and Medical Oncology, PROFESSOR | Oncological Sciences
Research Topics
Cancer Genetics, Cell Biology, DNA Repair, Drug Design and Discovery, Drug Resistance, Genomics, Molecular Biology, Signal Transduction, Tumor Suppressor Genes
Multi-Disciplinary Training Areas
Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS], Genetics and Genomic Sciences [GGS]
Education
BS/MS, Paris VII University
Instructor, Harvard Medical School
MS, Paris VI University
PhD, Max-Planck Institute for Developmental Biology, University of Tubingen, and Paris VI University
Postdoctoral fellowship, Dana-Farber Cancer Institute, Harvard Medical School
Awards
2016
Pershing Square Sohn Prize for Young Investigators in Cancer Research
2012
Young Scientist Cancer Research Award
2011
Searle Scholar
2009
Claudia Adams Barr Award in Cancer Research
2004
French Foundation for Medical Research (FRM) Scholarship
2003
French Association for Cancer Research (ARC) Scholarship
Research
Cancer target discovery in zebrafish (genetic and chemical-genetic approaches), mechanism of action of targeted therapies, development of molecular diagnostics. For more information, please visit the Sidi Laboratory.
Publications
Selected Publications
- Stepwise phosphorylation and SUMOylation of PIDD1 drive PIDDosome assembly in response to DNA repair failure. Richa B. Shah, Yuanyuan Li, Honglin Yu, Ela Kini, Samuel Sidi. Nature Communications
- A noncanonical IRAK4-IRAK1 pathway counters DNA damage–induced apoptosis independently of TLR/IL-1R signaling. Yuanyuan Li, Richa B. Shah, Samanta Sarti, Alicia L. Belcher, Brian J. Lee, Andrej Gorbatenko, Francesca Nemati, Honglin Yu, Zoe Stanley, Mahbuba Rahman, Zhengping Shao, Jose M. Silva, Shan Zha, Samuel Sidi. Science Signaling
- Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Christian Dubiella, Benika J. Pinch, Kazuhiro Koikawa, Daniel Zaidman, Evon Poon, Theresa D. Manz, Behnam Nabet, Shuning He, Efrat Resnick, Adi Rogel, Ellen M. Langer, Colin J. Daniel, Hyuk Soo Seo, Ying Chen, Guillaume Adelmant, Shabnam Sharifzadeh, Scott B. Ficarro, Yann Jamin, Barbara Martins da Costa, Mark W. Zimmerman, Xiaolan Lian, Shin Kibe, Shingo Kozono, Zainab M. Doctor, Christopher M. Browne, Annan Yang, Liat Stoler-Barak, Richa B. Shah, Nicholas E. Vangos, Ezekiel A. Geffken, Roni Oren, Eriko Koide, Samuel Sidi, Ziv Shulman, Chu Wang, Jarrod A. Marto, Sirano Dhe-Paganon, Thomas Look, Xiao Zhen Zhou, Kun Ping Lu, Rosalie C. Sears, Louis Chesler, Nathanael S. Gray, Nir London. Nature Chemical Biology
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Sidi has not yet completed reporting of Industry relationships.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.