
Sarah A Stanley, MBBCh, PhD
About Me
Sarah Stanley, MBBCh, PhD, is an Associate Professor of Medicine in the Division of Endocrinology, Diabetes and Bone Disease.
Dr. Stanley studied, trained and practiced as a physician at Cambridge University and London teaching hospitals, including The Royal London and The Hammersmith Hospital. Her work combined clinics for diabetes and rare endocrinology issues such as neuroendocrine tumors and pituitary disease with busy Internal Medicine intakes. Although she loved providing patient care, Dr. Stanley started to realize that most therapies were inadequate. In search of a bigger impact, she joined Professor Steve Bloom's Lab as a Wellcome fellow and completely her PhD (97-2000)"The role of orexigenic and anorexigenic peptides in the control of hypothalamo-pituitary axes". As a Medical Research Council fellow, she joined Professor Jeffrey Friedman's lab at Rockefeller University in 2005, working on murine models for CNS glucose sensing and later on the development of radio and magnetogenetics.
In 2014, Dr. Stanley joined Mount Sinai to start a new lab with joint appointments in Endocrinology and Neuroscience. Dr. Stanley is a member of the Mindich Child Health and Development Institute, the Center for Neurotechnology and Behavior and the Brain and Body research center. She believes the most important breakthroughs in medical research come at the intersection of existing fields and Mount Sinai was perfectly set up to enable these collaborations. The Stanley Laboratory's philosophy is simple: medical research requires both individual acumen and team work, and so she is on the lookout for research assistants and post doctoral scientists who combine personal drive with a real desire to learn in a collaborative setting.
Language
English
Position
ASSOCIATE PROFESSOR | Medicine, Endocrinology, Diabetes and Bone Disease, ASSOCIATE PROFESSOR | Neuroscience
Research Topics
Brain, Diabetes, Molecular Biology, Obesity
Multi-Disciplinary Training Areas
Neuroscience [NEU]
Education
BA, University of Cambridge
BChir, University of Cambridge
MB, University of Cambridge
PhD, Imperial College, London University
Awards
2016
Alexander and Alexandrine Sinsheimer Scholar Award
2016
Dr. Harold and Golden Lamport Research Award
2015
Cell Symposia: Engineering the Brain. Cellular Dynamics International Travel Award
Darwin Prize in Experimental Natural Sciences
Arthur Burrows Prize (Dermatology)
James Anderson Prize (Medicine and Surgery)
Research
Radiogenetics and Magnetogenetics
We are pioneering the use of radio waves and magnetic fields to stimulate individual cells and neurons - a technique that, like optogenetics, has broad research and therapeutic applications but which is non-invasive.
Nanobioengineering
We are developing the use of nanoparticles in bioengineered murine models for preclinical applications using ferritin and other naturally occurring nanoparticles.
Neuroendocrinology of diabetes
We are advancing the understanding of the interaction between central and peripheral systems in, and beyond, appetite control to find new approaches to Diabetes prevention and treatment.
We are fortunate to work in close collaboration with colleagues across Mount Sinai and in partnerships with Professor Jeffrey Friedman, Rockefeller University, and Professor Jonathan Dordick, Rensselaer Polytechnic Institute. Currently, our work is funded by The National Institutes of Health and American Diabetes Association.
Publications
Selected Publications
- Methylglyoxal is an antibacterial effector produced by macrophages during infection. Andrea Anaya-Sanchez, Samuel B. Berry, Scott Espich, Alex Zilinskas, Phuong M. Tran, Carolina Agudelo, Helia Samani, K. Heran Darwin, Daniel A. Portnoy, Sarah A. Stanley. Cell Host and Microbe
- Bidirectional regulation of motor circuits using magnetogenetic gene therapy. Santiago R. Unda, Lisa E. Pomeranz, Roberta Marongiu, Xiaofei Yu, Leah Kelly, Gholamreza Hassanzadeh, Henrik Molina, George Vaisey, Putianqi Wang, Jonathan P. Dyke, Edward K. Fung, Logan Grosenick, Rick Zirkel, Aldana M. Antoniazzi, Sofya Norman, Conor M. Liston, Chris Schaffer, Nozomi Nishimura, Sarah A. Stanley, Jeffrey M. Friedman, Michael G. Kaplitt. Science advances
- Obesity- and diet-induced plasticity in systems that control eating and energy balance. Carrie R. Ferrario, Heike Münzberg-Gruening, Linda Rinaman, J. Nicholas Betley, Stephanie L. Borgland, Monica Dus, Debra A. Fadool, Kathryn F. Medler, Gregory J. Morton, Darleen A. Sandoval, Claire B. de La Serre, Sarah A. Stanley, Kristy L. Townsend, Alan G. Watts, Padma Maruvada, Diana Cummings, Bradley M. Cooke. Obesity
