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Saurabh Mehandru, MD
Gastroenterology
About Me
Dr. Mehandru straddles the world of clinical care and laboratory based investigation. He graduated from the University College of Medical Sciences, Delhi University, India and then completed residency training in Internal Medicine at the NYU School of Medicine where he also served as Medical Chief Resident. He received subspecialty training in Clinical Gastroenterology at The Icahn School of Medicine at Mount Sinai.
Dr. Mehandru undertook post-doctoral training at the Rockefeller University, first working in the Laboratory of Dr. David Ho (with Dr. Martin Markowitz) and then in the Laboratory of Dr. Ralph Steinman, Nobel Laureate in Physiology or Medicine (2011).
During this period, Dr. Mehandru, reported on the preferential depletion of gut lymphocytes during acute HIV-1 infection and on the lack of immune reconstitution in the GI tract following years of apparently suppressive antiretroviral therapy.
After finishing his post-doctoral training, Dr. Mehandru was invited to join the faculty at Mount Sinai where in addition to serving as an Associate Professor of Gastroenterology, he leads a laboratory of Mucosal Immunology since 2013. Dr. Mehandru’s research interests include mucosal trafficking, the host-pathogen interface, dendritic cell biology and mucosal immunopathology in primary and acquired immunodeficiency states. He is an NIH-funded investigator who has received multiple awards.
Language
English
Position
PROFESSOR | Medicine, Gastroenterology, PROFESSOR | Immunology & Immunotherapy
Hospital Affiliations
- Mount Sinai Morningside
- The Mount Sinai Hospital
- Mount Sinai West
Research Topics
AIDS/HIV, Aging, Antigen Presentation, Autoimmunity, B Cells, Cell Adhesion, Cell Biology, Cellular Immunity, Chemokines, Cytokines, Dendritic Cells, Epithelial Cells, Gene Expressions, Hepatitis C Virus, Immune Deficiency, Immunology, Immunosuppression, Infectious Disease, Inflammation, Integrins, Knockout Mice, Lung, Lymphocytes, Macrophage, Microarray, Mucosal Immunology, Retinoic Acid, Retrovirus, T Cells, Trafficking
Multi-Disciplinary Training Areas
Immunology [IMM]
Clinical Focus
- Acid Reflux / Heartburn
- Angiodysplasia of the Colon
- Antibiotic-Associated Colitis-C Difficile
- Barrett's Esophagus
- Blood in Stool
- Celiac Disease
- Chronic Pancreatitis
- Colon Polyps
- Colorectal Cancer
- Constipation
- Crohn's Disease
- Diarrhea
- Dyspepsia
- Dysphagia
- Esophageal Cancer
- Familial Adenomatous Polyposis
- Gallstones
- Gastritis
- Gastroenterology
- Hemorrhoids
- Inflammatory Bowel Disease
- Iron-Deficiency Anemia
- Irritable Bowel Syndrome
- Jaundice
- Malabsorption
- Pancreatic Cancer
- Pancreatitis
- Peptic Ulcer
- Rectal Cancer
- Short Bowel Syndrome
- Stomach Cancer
- Stomach Pain
- Ulcerative Colitis
Education
MD, University College of Medical Sciences-Delhi
Residency, Psychiatry
University of Delhi
Residency, Internal Medicine
Bellevue Hospital Center
Fellowship, Gastroenterology
Mount Sinai Hospital
Certifications
American Board of Internal Medicine
Insurance Information
Accepted insurance may vary by the doctor’s office location. Please contact the office directly to obtain the most up-to-date insurance information.
- 1199 SEIU
- AETNA - Commercial
- AETNA - Medicare
- CIGNA Healthcare
- Centivo
- EmblemHealth - GHI-PPO
- EmblemHealth - HIP
- EmblemHealth - HIP-Medicare
- Empire Blue Cross Blue Shield - Commercial/Exchange
- Empire Blue Cross Blue Shield - Medicare
- HealthFirst Medicare
- Horizon NJ
- Magnacare-Health Care
- Medicare - NJ
- Medicare - NY
- Multiplan PHCS
- Oscar
- Oxford - Freedom and Liberty
- United Health Care - Commercial
- United Health Care - Empire Plan
- United Health Care - Oxford Care
- United Health Care - Top Tier
- VNSNY Choice Medicare
- VillageCareMax
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.
Publications
Selected Publications
- Anti-integrin αvβ6 Autoantibodies Are Increased in Primary Sclerosing Cholangitis Patients With Concomitant Inflammatory Bowel Disease and Correlate With Liver Disease Severity. Hannah Bloemen, Alexandra E. Livanos, Adrielly Martins, Richard Dean, Ana Catarina Bravo, Arno R. Bourgonje, Michael Tankelevich, Jake Herb, Judy Cho, André Anastácio Santos, Cecília M.P. Rodrigues, Francesca Petralia, Jean Frederic Colombel, Christopher L. Bowlus, Thomas Schiano, Joana Torres, Cynthia Levy, Saurabh Mehandru. Clinical Gastroenterology and Hepatology
- Targeting the SARS-CoV-2 reservoir in long COVID. Amy D. Proal, Soo Aleman, Morgane Bomsel, Petter Brodin, Marcus Buggert, Sara Cherry, Daniel S. Chertow, Helen E. Davies, Christopher L. Dupont, Steven G. Deeks, E. Wes Ely, Alessio Fasano, Marcelo Freire, Linda N. Geng, Diane E. Griffin, Timothy J. Henrich, Stephen M. Hewitt, Akiko Iwasaki, Harlan M. Krumholz, Michela Locci, Vincent C. Marconi, Saurabh Mehandru, Michaela Muller-Trutwin, Mark M. Painter, Etheresia Pretorius, David A. Price, David Putrino, Yu Qian, Nadia R. Roan, Dominique Salmon, Gene S. Tan, Michael B. VanElzakker, E. John Wherry, Johan Van Weyenbergh, Lael M. Yonker, Michael J. Peluso. The Lancet Infectious Diseases
- Gut IgA functionally interacts with systemic IgG to enhance antipneumococcal vaccine responses. Cindy Gutzeit, Emilie K. Grasset, Dean B. Matthews, Paul J. Maglione, Graham J. Britton, Haley Miller, Giuliana Magri, Lewis Tomalin, Matthew Stapylton, Pablo Canales-Herrerias, Musia Sominskaia, Mauricio Guzman, Marc Pybus, Sonia Tejedor Vaquero, Lin Radigan, Roser Tachó-Piñot, Andrea Martín Nalda, Marina García Prat, Monica Martinez Gallo, Romina Dieli-Crimi, José C. Clemente, Saurabh Mehandru, Mayte Suarez-Farinas, Jeremiah J. Faith, Charlotte Cunningham-Rundles, Andrea Cerutti. Science advances
Patient Experience Star Ratings and Comments
The Patient Experience Star Rating reflects our patients’ perception of how well their Mount Sinai provider communicated with them during an office visit. The Star Rating is based on patient responses to three questions on a patient experience survey, a standardized questionnaire sent to verified patients and distributed by a third party vendor, Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score.
Great doctor, I'll recommend him any time.
Was very satisfied with the primary care doctor and would recommend them to everyone.
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Below are financial relationships with industry reported by Dr. Mehandru during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- Bristol-Myers Squibb
- Genentech, Inc.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.