
Schahram Akbarian, MD, PhD
About Me
Schahram Akbarian studied medicine and conducted his thesis work on the central representation of the primate vestibular system at the Freie Universitaet Berlin, Germany. He is a board certified psychiatrist and molecular neuroscientist who trained at the Massachusetts General Hospital in Boston, the Whitehead Institute for Biomedical Research in Cambridge and the University of California at Irvine. In 2002, he joined the University of Massachusetts Medical School in Worcester where he established a research program in psychiatric epigenetics and served as the Director of the Brudnick Neuropsychiatric Research Institute. Presently, he heads the Division of Psychiatric Epigenomics in the Departments of Psychiatry and Neuroscience at Mount Sinai School of Medicine.
He is a former recipient of the Klerman award from the Brain & Behavior Research Foundation, the Judith Silver Memorial award of the National Alliance for the Mentally Ill, the Outstanding resident award of the National Institute of Mental Health and the Eva King Killam Research Award of the American College of Neuropsychopharmacology. Dr. Akbarian has been a principal investigator on National Institutes of Health-funded research projects and grants since 2001and published close to 100 articles in scientific journals and book chapters. He is a member of professional societies such as the American College of Neuropsychopharmacology (ACNP) and presently serves on the Scientific Advisory Board of the Brain & Behavior Research Foundation (BBRF, formerly NARSAD), the American Foundation for Suicide Prevention and the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). He serves on Editorial Boards of various journals in the field, including Biological Psychiatry, Neuropsychopharmacology, Schizophrenia Bulletin and European Neuropsychopharmacology.
Visit Dr. Akbarian's Laboratory of Epigenetic Regulation of the Human Brain and Mount Sinai Conte Center on Epigenetic Mechanisms of Depression for more information.
Language
English
Position
PROFESSOR | Genetics and Genomic Sciences, PROFESSOR | Psychiatry, PROFESSOR | Neuroscience
Research Topics
Depression, Schizophrenia
Multi-Disciplinary Training Areas
Disease Mechanisms and Therapeutics (DMT), Neuroscience [NEU]
Research
Key words: nucleosome, epigenome, histone methylation, neuronal nucleus, prefrontal cortex, mood disorder, schizophrenia, autism spectrum disorder
Publications
Selected Publications
- Altered tRNA expression profile associated with codon-specific proteomic changes in the suicide brain. J. Blaze, S. Chen, S. Heissel, H. Alwaseem, M. P. Landinez Macias, C. Peter, H. Molina, E. Storkebaum, G. Turecki, H. Goodarzi, S. Akbarian. Molecular Psychiatry
- Somatic instability of the FGF14-SCA27B GAA•TTC repeat reveals a marked expansion bias in the cerebellum. David Pellerin, Jean Loup Méreaux, Susana Boluda, Matt C. Danzi, Marie Josée Dicaire, Claire Sophie Davoine, David Genis, Guinevere Spurdens, Catherine Ashton, Jillian M. Hammond, Brandon J. Gerhart, Viorica Chelban, Phuong U. Le, Maryam Safisamghabadi, Christopher Yanick, Hamin Lee, Sathiji K. Nageshwaran, Gabriel Matos-Rodrigues, Zane Jaunmuktane, Kevin Petrecca, Schahram Akbarian, André Nussenzweig, Karen Usdin, Mathilde Renaud, Céline Bonnet, Gianina Ravenscroft, Mario A. Saporta, Jill S. Napierala, Henry Houlden, Ira W. Deveson, Marek Napierala, Alexis Brice, Laura Molina Porcel, Danielle Seilhean, Stephan Zuchner, Alexandra Durr, Bernard Brais. Brain
- Multiomic single-cell profiling identifies critical regulators of postnatal brain. Tereza Clarence, Jaroslav Bendl, Xuan Cao, Xinyi Wang, Shiwei Zheng, Gabriel E. Hoffman, Alexey Kozlenkov, Aram Hong, Marina Iskhakova, Manoj K. Jaiswal, Sarah Murphy, Alexander Yu, Vahram Haroutunian, Stella Dracheva, Schahram Akbarian, John F. Fullard, Guo Cheng Yuan, Donghoon Lee, Panos Roussos. Nature Genetics