Serre-Yu Wong
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Serre-Yu Wong, MD, PhD


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About Me

Serre-Yu Wong, MD, PhD, is an Assistant Professor in the Division of Gastroenterology in the Department of Medicine. She specializes in the care of patients with inflammatory bowel disease, including Crohn’s disease and ulcerative colitis.

Dr. Wong’s research focus is on how inflammation begins in Crohn’s disease. Through basic and translational research, she studies how microbes interact with our intestinal tissue and immune system.

Dr. Wong brings her unique lens to patients and science to perianal Crohn’s disease. She established the perianal Crohn’s clinic with colorectal surgeon Dr. Sergey Khaitov with the goal of combining collaborative multidisciplinary strategies, state-of-the-art care, and clinical trials to improve the lives of patients with perianal Crohn’s disease. Dr. Wong is a member of the international fistula consortium that works to guide management and research in the field of fistulizing Crohn’s disease.

During the COVID-19 pandemic, Dr. Wong founded the ICARUS-IBD to study serological responses to SARS-CoV-2 infection and vaccination in patients with IBD. ICARUS-IBD was the first study in the world to report anti-SARS-CoV-2 antibody levels after COVID-19 vaccination in IBD patients. Dr. Wong continues to lead this consortium of 13 centers in 9 countries across North America, Asia, and Europe as it moves forward to understand the science of how this virus affects the immune system of patients with IBD.

Dr. Wong received her MD and PhD in Molecular Oncology and Immunology from the New York University School of Medicine. She completed her residency in internal medicine and fellowship in gastroenterology at Mount Sinai. Her research been funded by The Crohn’s and Colitis Foundation, The Leona M. and Harry B. Helmsley Charitable Trust, NIH, and the American College of Gastroenterology. She was a former Ruth and Gerald Dickler Scholar in Inflammatory Bowel Diseases.

ASSISTANT PROFESSOR | Medicine, Gastroenterology
Hospital Affiliations
  • Mount Sinai Beth Israel
  • Mount Sinai Morningside
  • Mount Sinai Brooklyn
  • Mount Sinai Queens
  • The Mount Sinai Hospital
  • Mount Sinai West