Shu-Hsia Chen, PhD

About Me
Education & Certifications
Research
Locations
Publications
Industry Relationships

About Me

Language

English

Position

ADJUNCT PROFESSOR | Oncological Sciences

Research Topics

Anti-Tumor Therapy, Antigen Presentation, Autoimmunity, Cancer, Dendritic Cells, Gene Therapy, Hematopoiesis, Immune Antagonism, Immunological Tolerance, Immunology, Lymphoma, Microarray, Stem Cells, T Cells, Tolerance, Transplantation, Tumorigenesis

Multi-Disciplinary Training Areas

Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS], Disease Mechanisms and Therapeutics (DMT), Immunology [IMM], Microbiology [MIC]

About Me

Language

English

Position

ADJUNCT PROFESSOR | Oncological Sciences

Research Topics

Multi-Disciplinary Training Areas

Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS], Disease Mechanisms and Therapeutics (DMT), Immunology [IMM], Microbiology [MIC]

Education

BA, Soochow University

MS, National Yang-Ming Medical University

PhD, National Yang-Ming Medical University

Research

Malignant metastases present one of the most challenging roadblocks to cancer treatment. In order to develop a treatment modality for metastatic tumors, my lab is focusing on strategies for immune modulated cancer gene therapies. This promising approach has shown up to 100-1000 times higher concentrations of cytokines in situ, attracted dendritic cells (DCs) and inflammatory cells to the tumor site, yet reduced the systemic toxicity mediated by the cytokines. Specifically, my laboratory is pursuing two major directions, immune enhancement and immune tolerance.

Locations

Icahn (East) Building Floor 13 Room 13-20B, 1425 Madison Ave, New York, NY, 10029

212-659-8256

Icahn (East) Building Floor 15 Room 15-20A, 1425 Madison Ave, New York, NY, 10029

Publications

Publications:136

Selected Publications

Novel platinum therapeutics induce rapid cancer cell death through triggering intracellular ROS storm. Yongbin Liu, Dongfang Yu, Xueying Ge, Lingyi Huang, Ping Ying Pan, Haifa Shen, Roderic I. Pettigrew, Shu Hsia Chen, Junhua Mai. Biomaterials
Characterization of the Breast Cancer Liver Metastasis Microenvironment via Machine Learning Analysis of the Primary Tumor Microenvironment. Dylan A. Goodin, Eric Chau, Junjun Zheng, Cailin O'Connell, Anjana Tiwari, Yitian Xu, Polly Niravath, Shu Hsia Chen, Biana Godin, Hermann B. Frieboes. Cancer Research Communications
Nanofluidic delivery implant sustains localization and maximizes efficacy of intratumoral immunotherapy. Hsuan Chen Liu, Nicola Di Trani, Marzia Conte, Dinh Chuong Nguyen, Simbarashe Jokonya, Abe Wu, Robin Vander Pol, Ashley L. Joubert, Ilaria Facchi, Anthony M. Wood, Jeremy Ho, Federica Pesaresi, Valentina Cauda, Shu Hsia Chen, Xuewu Liu, Patrick S. Stayton, Corrine Ying Xuan Chua, Alessandro Grattoni. Nano Today

View All Publications

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Dr. Chen has not yet completed reporting of Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.

Dr. Chen has not yet completed reporting of Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.