Steven G Coca
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Steven G Coca, DO

Internal Medicine, Nephrology

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About Me

Steven G. Coca, DO, MS, is a Professor of Medicine at the Icahn School of Medicine at Mount Sinai, the Associate Chair for Clinical and Translational Research for the Department of Internal Medicine, and the Director of Clinical Research for the Division of Nephrology.

Dr. Coca’s research accomplishments are diverse and far-reaching: he has focused research efforts on short- and long-term outcomes of acute kidney injury, and assessing performance of biomarkers for rapid diagnosis and risk stratification in AKI. His research has advanced understanding of the clinical utility of prognostic, predictive, and efficacy biomarkers for CKD/diabetic kidney disease in several large cohort studies, including the ACCORD, VA NEPHRON-D, CANVAS, and DAPA-CKD clinical trials, as well as the Mount Sinai BioMe Biobank and the UPenn Medicine Biobank. He has been an active investigator in several large NIH consortia, including the TRIBE-AKI, ASSESS-AKI, CKD Biocon, and Kidney Precision Medicine Project (KPMP). Over the past 3 years, he has led collaborations to advance use of machine-learning techniques and multidimensional data acquisition to create risk-stratification tools for patients at risk or with prevalent chronic kidney disease, and studied the impact of exercise on longitudinal changes in the kidney. His work has led to the FDA approval and commercial implementation of the bioprognostic test, KidneyIntelX, a validated risk score for progression of CKD in adults with type 2 diabetes.

Since 2005, Dr. Coca has published numerous peer-reviewed research articles, reviews, and editorials, and has given numerous invited talks at national and international conferences and academic medical centers. He has engaged in multiple collaborative efforts in translational and clinical research, and served as a research mentor for many fellows, residents, medical students, and junior faculty members.  He also serves on the editorial boards for the Journal of the American Society of Nephrology, the Clinical Journal of the American Society of Nephology, and Kidney International, and as an Associate Editor for Kidney360, and is a frequent reviewer on NIH study sections.

Dr. Coca received his D.O. degree from the University of New England College of Osteopathic Medicine, and completed his residency and nephrology fellowship at the Yale University School of Medicine. He received his Master of Science in Epidemiology and Public Health from the Yale University Graduate School of Arts and Sciences.

Language
English
Position
PROFESSOR | Medicine, Nephrology
Hospital Affiliations
  • Mount Sinai Queens
  • The Mount Sinai Hospital

Clinical Focus

Video

Education

DO, University of New England College of Osteopathic Medicine
MS, Yale University Graduate School of Arts and Sciences
Residency, Internal Medicine

Yale University School of Medicine

Fellowship, Nephrology

Yale University School of Medicine

Certifications

American Board of Internal Medicine

Awards

2021

ASN

Midcareer Distinguished Researcher Award

2021

Top Reviewer Award

American Journal of Nephrology

2019

MSIP

“Deal of the Year Award” (for RenalytixAI; shared with Drs. Murphy and Nadkarni)

2018

Stanley L. Cohen Memorial Lecture & Award

Yale New Haven/Bridgeport Hospital Foundation

2017

Joseph R. Renda Memorial Award

Yale University School of Medicine

2013

AFMR 2013 Junior Physician Investigator Award

American Federation for Medical Research

2013

Junior Physician Investigator Award

American Federation for Medical Research

2008

T. Franklin Williams Scholar

2008

K23 Career Development Award

NIH/NIDDK

2008

NIH Loan Repayment Program

NIH

2008

ASN

ASP Junior Development Grant in Geriatric Nephrology

2007

Henry Christian Award

American Federation for Medical Research

2002

Intern of the Year

Yale Primary Care Internal Medicine Program

Midcareer Distinguished Researcher Award,

American Society of Nephrology

Top 5 Reviewer of the Year

Journal of the American Society of Nephrology

Top 5 Reviewer of the Year

Clinical Journal of the American Society of Nephrology

MSIP “Deal of the Year Award”

(for RenalytixAI; shared with Drs. Murphy and Nadkarni)

Top 5 Reviewer of the Year,

Journal of the American Society of Nephrology

Top 5 Reviewer of the Year,

Clinical Journal of the American Society of Nephrology

4D Technology Development Program Award

SINAInnovations

Henry Christian Award

American Federation for Medical Research

Research

Dr. Coca is actively involved in clinical and translational research that focuses on using biomarkers to improve risk-stratification for outcomes in acute and chronic kidney disease. The development of prognostic and predictive biomarkers may aide future clinical trials, by serving as an enrichment strategy for enrollment, and may also serve as outcomes for early phase trials of novel interventions. He has leveraged existing cohorts with banked blood and urine samples, including the ACCORD, VA NEPHRON-D, CANVAS, and DAPA-CKD clinical trials, as well as the Mount Sinai BioMe Biobank and the UPenn Medicine Biobank to explore the prognostic, discriminative, and additional value of biomarkers in AKI and CKD. He has been an active investigator in several large NIH consortia, including the TRIBE-AKI, ASSESS-AKI, CKD Biocon, and Kidney Precision Medicine Project (KPMP). He plans to continue exploring these parameters in other large cohorts and then to design innovative trials employing biomarkers for facilitated enrollment and for better determination of efficacy of existing or new agents.

Insurance Information

Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).

Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.

Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.

Publications

Publications:320
Selected Publications

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Coca during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Founder/Co-Founder/Partner

  • Renalytix AI, Inc

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.