Publications:472
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Accepting New PatientsTerry F Davies, MD
Internal Medicine, Endocrine, Diabetes and Bone Diseases (Endocrinology)
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About Me
Terry Francis Davies is the Florence and Theodore Baumritter Professor of Medicine at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Davies was trained in the UK, at the University of Newcastle and after further research experience at the National Institutes of Health in Bethesda, Maryland, he has spent most of his career in New York at Mount Sinai.
Dr. Davies has a distinguished record of significant contributions to our understanding of endocrine physiology and pathology having published over 400 scientific papers mostly concerning thyroid disease at both a basic level, in the areas of immunology and genetics, and in the clinical arena in the area of autoimmune thyroid disease (AITD) and AITD in pregnancy. The Davies Laboratory remains one of the pre-eminent sites for autoimmune thyroid disease research as evidenced by his extensive support from the National Institutes of Health, since 1980, and from the VA Research Program.
Dr. Davies has received many honors in his career, is a member of the American Association of Physicians and a past President of the American Thyroid Association (ATA). In 2010 Dr. Davies was awarded the John B Stanbury Medal for Thyroid Physiology and in 2012 he was made an Honorary Fellow of his home university in Newcastle, UK.
The state of Florida requires out-of-state professionals who are registered to provide telehealth services to display a hyperlink to the Florida Department of Health telehealth web page. This allows Florida patients who are receiving medical care by telehealth to confirm the provider’s licensure and Florida registration.
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Brooklyn
- The Mount Sinai Hospital
- New York Eye and Ear Infirmary of Mount Sinai
Research Topics
Autoimmunity, Genetics, Receptors, Stem Cells, T Cells, Thyroid
About Me
Terry Francis Davies is the Florence and Theodore Baumritter Professor of Medicine at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Davies was trained in the UK, at the University of Newcastle and after further research experience at the National Institutes of Health in Bethesda, Maryland, he has spent most of his career in New York at Mount Sinai.
Dr. Davies has a distinguished record of significant contributions to our understanding of endocrine physiology and pathology having published over 400 scientific papers mostly concerning thyroid disease at both a basic level, in the areas of immunology and genetics, and in the clinical arena in the area of autoimmune thyroid disease (AITD) and AITD in pregnancy. The Davies Laboratory remains one of the pre-eminent sites for autoimmune thyroid disease research as evidenced by his extensive support from the National Institutes of Health, since 1980, and from the VA Research Program.
Dr. Davies has received many honors in his career, is a member of the American Association of Physicians and a past President of the American Thyroid Association (ATA). In 2010 Dr. Davies was awarded the John B Stanbury Medal for Thyroid Physiology and in 2012 he was made an Honorary Fellow of his home university in Newcastle, UK.
The state of Florida requires out-of-state professionals who are registered to provide telehealth services to display a hyperlink to the Florida Department of Health telehealth web page. This allows Florida patients who are receiving medical care by telehealth to confirm the provider’s licensure and Florida registration.
Language
Position
Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Brooklyn
- The Mount Sinai Hospital
- New York Eye and Ear Infirmary of Mount Sinai
Research Topics
Autoimmunity, Genetics, Receptors, Stem Cells, T Cells, Thyroid
Clinical Focus
- Biopsy
- Doppler Ultrasound
- Graves Disease
- Hashimoto's Disease
- Hyperparathyroidism
- Hyperthyroidism
- Hypoparathyroidism
- Hypothyroidism
- Osteopenia
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Education
MBBS, University of Newcastle-Upon-Tyne
MD, University of New Castle-Upon-Tyne
Residency, Internal Medicine
Newcastle University Medical School
Residency, Endocrinology, Diabetes and Metabolism
Newcastle University Medical School
Fellowship, Endocrinology, Diabetes and Metabolism
National Cancer Institute, NIH
Certifications
American Board of Internal Medicine
Awards
2009
Best Doctors
New York Magazine
2008
President Elect
American Thyroid Association
2008
Invited lecture
International Autoimmunity Conference, Porto, Portugal
2007
Honorary President for Life
United States Friends of Newcastle University
2006
Veterans Affairs Merit Award
2006
Invited Lecture
International Autoimmunity Congress, Sorrento, Italy
2006
Plenary Lecture
Canadian Society for Endocrinology, Toronto
2005
Plenary Lecture
German Endocrine Society, Muenster
2004
Plenary Lecture
4th International Congress on Autoimmunity, Budapest, Hungary
2003
Plenary Lecture
Australian Endocrine Society, Melbourne
2002
Higgins Award
Thyroid Foundation of America
Research
Specific Clinical/Research Interest:
Mechanisms in autoimmune disease with an emphasis on autoimmune thyroid disease
Postdoctoral Fellows: Marco Agote-Robertson PhD, Sayed Moshad PhD, Chris Michalek MD, PhD, Risheng Ma, PhD
Research Personnel: Rauf Latif PhD, Xiaoming Yin PhD, Zhong Yao
Summary of Research Studies:
Research areas of emphasis include: The TSH receptor molecule: This is the major autoantigen in human Graves' disease which is a form of autoimmune hyperthyroidism. The TSHR remains an elusive quarry ten years after it was cloned becsue of its highly complex processing. Our emphasis is on the post translational processing events involved with multimerization and intramolecular cleavage of the TSHR and its status in lipid rafts. Complex Genetics: The aim of this research has been to detect the susceptibility genes for autoimmune thyroid disease using genome screening of informative families with Graves' disease and/or Hashimoto's thyroiditis. Our group has experience in the analysis of families with these disorders and we have a large collection of well characterized families to study. Currently, our areas of emphasis are on individual susceptibility genes. In particular the TSH receptor intron 1 region where we have identified miRNAs close to associated SNPs and the role of epigenetics(using X chromosome inactivation) in disease susceptibility and its influence on the autoimmune response. Animal models of autoimmune thyroid disease: We have developed models of hyperthyroid mice immunized with an adenoviral vector incorporating the TSH receptor as a model for Graves' disease. These studies involve the development and characterization of unique monoclonal antibodies to the TSH receptor with thyroid stimulating activity with an emphasis on epitope characterization and signal transduction.
Mechanisms in autoimmune disease with an emphasis on autoimmune thyroid disease
Postdoctoral Fellows: Marco Agote-Robertson PhD, Sayed Moshad PhD, Chris Michalek MD, PhD, Risheng Ma, PhD
Research Personnel: Rauf Latif PhD, Xiaoming Yin PhD, Zhong Yao
Summary of Research Studies:
Research areas of emphasis include: The TSH receptor molecule: This is the major autoantigen in human Graves' disease which is a form of autoimmune hyperthyroidism. The TSHR remains an elusive quarry ten years after it was cloned becsue of its highly complex processing. Our emphasis is on the post translational processing events involved with multimerization and intramolecular cleavage of the TSHR and its status in lipid rafts. Complex Genetics: The aim of this research has been to detect the susceptibility genes for autoimmune thyroid disease using genome screening of informative families with Graves' disease and/or Hashimoto's thyroiditis. Our group has experience in the analysis of families with these disorders and we have a large collection of well characterized families to study. Currently, our areas of emphasis are on individual susceptibility genes. In particular the TSH receptor intron 1 region where we have identified miRNAs close to associated SNPs and the role of epigenetics(using X chromosome inactivation) in disease susceptibility and its influence on the autoimmune response. Animal models of autoimmune thyroid disease: We have developed models of hyperthyroid mice immunized with an adenoviral vector incorporating the TSH receptor as a model for Graves' disease. These studies involve the development and characterization of unique monoclonal antibodies to the TSH receptor with thyroid stimulating activity with an emphasis on epitope characterization and signal transduction.
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- Department of Medicine-Endocrinology5 East 98th Street, 3rd Floor, New York, NY, 10029
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Publications
Selected Publications
- Mechanisms in Thyroid Eye Disease: The TSH Receptor Interacts Directly with the IGF-1 Receptor. Rauf Latif, Mihaly Mezei, Terry F. Davies. Endocrinology
- Hypothyroidism Induced by a TSH Receptor Peptide—Implications for Thyroid Autoimmunity. Pingping Xiang, Rauf Latif, Syed Morshed, Terry F. Davies. Thyroid
- The TSH Receptor Antibody Reactome Contributes to Retro-Orbital Inflammation. Syed Morshed, Maryam Mansoori, Terry F. Davies. Journal of the Endocrine Society
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Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Below are financial relationships with industry reported by Dr. Davies during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- GLG Network
- Hollingsworth LLP
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Below are financial relationships with industry reported by Dr. Davies during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- GLG Network
- Hollingsworth LLP
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.